Suicidal cross-linking of PARP-1 to AP site intermediates in cells undergoing base excision repair.
about
Accessing DNA damage in chromatin: Preparing the chromatin landscape for base excision repairEnhancing the Cytotoxic Effects of PARP Inhibitors with DNA Demethylating Agents - A Potential Therapy for CancerInterstrand cross-links arising from strand breaks at true abasic sites in duplex DNA.Base excision repair defects invoke hypersensitivity to PARP inhibition.Mammalian Base Excision Repair: Functional Partnership between PARP-1 and APE1 in AP-Site Repair.Micro-irradiation tools to visualize base excision repair and single-strand break repairTumor-selective use of DNA base excision repair inhibition in pancreatic cancer using the NQO1 bioactivatable drug, β-lapachone.Widespread transcriptional gene inactivation initiated by a repair intermediate of 8-oxoguanine.Poly(ADP-ribose) polymerases covalently modify strand break termini in DNA fragments in vitro.Regulation of DNA Alkylation Damage Repair: Lessons and Therapeutic Opportunities.Risky repair: DNA-protein crosslinks formed by mitochondrial base excision DNA repair enzymes acting on free radical lesions.Base excision repair enzymes protect abasic sites in duplex DNA from interstrand cross-linksAlkylation induced cerebellar degeneration dependent on Aag and Parp1 does not occur via previously established cell death mechanisms.Unencumbered Pol β lyase activity in nucleosome core particles.PARP inhibitors protect against sex- and AAG-dependent alkylation-induced neural degeneration.Reactivity and Cross-Linking of 5'-Terminal Abasic Sites within DNA.Biochemical Characterization of AP Lyase and m6A Demethylase Activities of Human AlkB Homologue 1 (ALKBH1).PARP1 changes from three-dimensional DNA damage searching to one-dimensional diffusion after auto-PARylation or in the presence of APE1.Formation and repair of DNA-protein crosslink damage.
P2860
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P2860
Suicidal cross-linking of PARP-1 to AP site intermediates in cells undergoing base excision repair.
description
2014 nî lūn-bûn
@nan
2014 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Suicidal cross-linking of PARP ...... dergoing base excision repair.
@ast
Suicidal cross-linking of PARP ...... dergoing base excision repair.
@en
type
label
Suicidal cross-linking of PARP ...... dergoing base excision repair.
@ast
Suicidal cross-linking of PARP ...... dergoing base excision repair.
@en
prefLabel
Suicidal cross-linking of PARP ...... dergoing base excision repair.
@ast
Suicidal cross-linking of PARP ...... dergoing base excision repair.
@en
P2093
P2860
P921
P356
P1476
Suicidal cross-linking of PARP ...... ndergoing base excision repair
@en
P2093
Bret D Freudenthal
Esther W Hou
Julie K Horton
Paul D Chastain
Rajendra Prasad
P2860
P304
P356
10.1093/NAR/GKU288
P407
P577
2014-04-25T00:00:00Z