Copy-neutral loss of heterozygosity is prevalent and a late event in the pathogenesis of FLT3/ITD AML - Wikidata - wikimedia - TriplyDB

Copy-neutral loss of heterozygosity is prevalent and a late event in the pathogenesis of FLT3/ITD AML

Copy-neutral loss of heterozygosity is prevalent and a late event in the pathogenesis of FLT3/ITD AML

http://www.wikidata.org/entity/Q33702150

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Revealing very small FLT3 ITD mutated clones by ultra-deep sequencing analysis has important clinical implications in AML patients.CDKN2B, SLC19A3 and DLEC1 promoter methylation alterations in the bone marrow of patients with acute myeloid leukemia during chemotherapy Molecular synergy underlies the co-occurrence patterns and phenotype of NPM1-mutant acute myeloid leukemia.FLT3-ITD and its current role in acute myeloid leukaemia.Prognostic significance of acquired copy-neutral loss of heterozygosity in acute myeloid leukemia.Genomic instability is a principle pathologic feature of FLT3 ITD kinase activity in acute myeloid leukemia leading to clonal evolution and disease progression.Distinct age-associated molecular profiles in acute myeloid leukemia defined by comprehensive clinical genomic profiling.Knock-in of the R394W mutation causes MDS and cooperates with to drive aggressive myeloid neoplasms in mice

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Copy-neutral loss of heterozygosity is prevalent and a late event in the pathogenesis of FLT3/ITD AML

http://www.wikidata.org/entity/Q33702150

description

2014 nî lūn-bûn

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2014 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2014 թվականի մայիսին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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Copy-neutral loss of heterozyg ...... e pathogenesis of FLT3/ITD AML

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Copy-neutral loss of heterozyg ...... e pathogenesis of FLT3/ITD AML

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Copy-neutral loss of heterozyg ...... e pathogenesis of FLT3/ITD AML

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Copy-neutral loss of heterozyg ...... e pathogenesis of FLT3/ITD AML

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Copy-neutral loss of heterozyg ...... e pathogenesis of FLT3/ITD AML

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Copy-neutral loss of heterozyg ...... e pathogenesis of FLT3/ITD AML

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Blood Cancer Journal

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Copy-neutral loss of heterozyg ...... e pathogenesis of FLT3/ITD AML

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D L Stirewalt

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E L Pogosova-Agadjanyan

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J Joaquin

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K Tsuchiya

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S Meshinchi

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P2860

Statistical significance for genomewide studies

Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignancies.

The impact of FLT3 internal tandem duplication mutant level, number, size, and interaction with NPM1 mutations in a large cohort of young adult patients with acute myeloid leukemia.

Prognostic impact of FLT3-ITD load in NPM1 mutated acute myeloid leukemia.

A comparison of normalization methods for high density oligonucleotide array data based on variance and bias

Exploration, normalization, and summaries of high density oligonucleotide array probe level data

Efficacy and safety of gemtuzumab ozogamicin in patients with CD33-positive acute myeloid leukemia in first relapse

Mouse model of Noonan syndrome reveals cell type- and gene dosage-dependent effects of Ptpn11 mutation

ArrayExpress--a public repository for microarray gene expression data at the EBI

Prevalence and prognostic significance of Flt3 internal tandem duplication in pediatric acute myeloid leukemia.

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10.1038/BCJ.2014.27

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4

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