Engineered knottin peptides: a new class of agents for imaging integrin expression in living subjects.
about
Challenging the state of the art in protein structure prediction: Highlights of experimental target structures for the 10th Critical Assessment of Techniques for Protein Structure Prediction Experiment CASP10Fragmentation follows structure: top-down mass spectrometry elucidates the topology of engineered cystine-knot miniproteinsDual-purpose linker for alpha helix stabilization and imaging agent conjugation to glucagon-like peptide-1 receptor ligands.Molecular ultrasound assessment of tumor angiogenesisUse of (64)Cu-labeled fibronectin domain with EGFR-overexpressing tumor xenograft: molecular imaging.Engineered cystine knot peptides that bind alphavbeta3, alphavbeta5, and alpha5beta1 integrins with low-nanomolar affinity.An engineered knottin peptide labeled with 18F for PET imaging of integrin expression.Cystine-knot peptides engineered with specificities for α(IIb)β(3) or α(IIb)β(3) and α(v)β(3) integrins are potent inhibitors of platelet aggregation.Functional mutation of multiple solvent-exposed loops in the Ecballium elaterium trypsin inhibitor-II cystine knot miniprotein.Peptides and peptide hormones for molecular imaging and disease diagnosisFluorescent analogs of biomolecular building blocks: design, properties, and applications.Phage display and molecular imaging: expanding fields of vision in living subjects.Coordinating radiometals of copper, gallium, indium, yttrium, and zirconium for PET and SPECT imaging of diseaseA Bioengineered Peptide that Localizes to and Illuminates Medulloblastoma: A New Tool with Potential for Fluorescence-Guided Surgical ResectionEvaluation of a (64)Cu-labeled cystine-knot peptide based on agouti-related protein for PET of tumors expressing alphavbeta3 integrinA radiofluorinated divalent cystine knot peptide for tumor PET imaging.A dual-labeled knottin peptide for PET and near-infrared fluorescence imaging of integrin expression in living subjects.Peptide aptamers: development and applications.Engineering agatoxin, a cystine-knot peptide from spider venom, as a molecular probe for in vivo tumor imagingMonoclonal antibody therapeutics with up to five specificities: functional enhancement through fusion of target-specific peptides.Exploring new near-infrared fluorescent disulfide-based cyclic RGD peptide analogs for potential integrin-targeted optical imaging.PET imaging of tumor neovascularization in a transgenic mouse model with a novel 64Cu-DOTA-knottin peptide.High throughput screening identifies disulfide isomerase DsbC as a very efficient partner for recombinant expression of small disulfide-rich proteins in E. coli.Integrin targeted delivery of radiotherapeutics.Macrocyclic chelator assembled RGD multimers for tumor targeting.Combinatorial optimization of cystine-knot peptides towards high-affinity inhibitors of human matriptase-1Multimodal silica nanoparticles are effective cancer-targeted probes in a model of human melanoma.Cystine-knot peptides targeting cancer-relevant human cytotoxic T lymphocyte-associated antigen 4 (CTLA-4).PET Imaging of Integrin Positive Tumors Using F Labeled Knottin Peptides.Pharmacokinetically stabilized cystine knot peptides that bind alpha-v-beta-6 integrin with single-digit nanomolar affinities for detection of pancreatic cancerStroma targeting nuclear imaging and radiopharmaceuticals.Quantitative analysis and parametric imaging of 18F-labeled monomeric and dimeric RGD peptides using compartment model.High Proteolytic Resistance of Spider-Derived Inhibitor Cystine KnotsStatins Reduce Melanoma Development and Metastasis through MICA Overexpression.Design and development of molecular imaging probes.Engineered knottin peptide enables noninvasive optical imaging of intracranial medulloblastoma.A practical guide to the construction of radiometallated bioconjugates for positron emission tomography.Alternative Non-Antibody Protein Scaffolds for Molecular Imaging of CancerCopper-64 radiopharmaceuticals for PET imaging of cancer: advances in preclinical and clinical research.Protein scaffold-based molecular probes for cancer molecular imaging.
P2860
Q27680838-A5421A52-4101-4EF6-991D-EE7A14CC730CQ28543684-0FF302E0-2170-4951-8FA0-37072DB3407DQ30379845-20F5F48D-C26A-4A9B-8528-2A9D082D357DQ30474770-83FDAA00-E3F8-4990-82E6-39FB83B49F95Q30511916-AA588603-6BAD-4988-AAF1-29767E058E61Q33447473-A3B12ED6-E23C-400E-B457-2A7AA4B4AA5AQ33581665-DAFCD98F-5FF7-4536-BF19-F58825C83BECQ33782671-CC297834-BE4B-4773-BC53-AF8F84D4D390Q33833584-9887297B-B73D-4234-B5B5-892BE78F97E2Q33846924-3D5E2003-8085-4809-A10F-2B2EEFE91C13Q33846993-BB97CF1F-E5DB-4A09-AB99-26366925BC9AQ33849788-D6463377-5939-44A8-A027-8561173E1F33Q33870879-08382AB6-FB80-4EB6-A5E2-F02DE72F9398Q33914493-25291F5D-845A-4162-ABD0-AE6CA1E02FA3Q34083412-D97A8805-81E1-4F4B-82F3-A5C2E69F9DAEQ34416172-69CE81A9-A509-484B-B74D-12A32DE430E7Q34419762-73621581-E67E-4AD0-A857-2B66078C9DEFQ34471346-4EFC872E-D86C-4940-BB66-DBAC5964A130Q34662001-ACA0EC61-1CD3-498E-8AF6-C52EA9FAF989Q34662933-8092E70D-2B3A-4071-9BD1-542A2C746CFCQ34669572-9BE5F699-B035-433E-9BA1-ECD1700EDE61Q34677001-9141DA25-8092-45DD-AD8E-87D79B5F85B6Q34680566-842B427C-42D4-48F3-985C-854AD381DC4EQ34912696-EF83D709-9494-4226-8800-34C27F1DF27AQ34995512-DCCF8619-F2BD-4317-9320-E30890D01C2FQ35023006-A82536FF-269E-4B43-BB60-88029A546BA7Q35572430-DE1F8AF1-A006-4E8D-92F2-0B96EB141BB3Q35627631-F2F88945-B0F2-49C4-88AC-D2FB28C700FBQ35641937-C5CCEDEB-D98C-4702-8611-A513AC86F802Q35729996-57849C50-40A2-446C-8A7F-A27FA3E70648Q35999606-E89BEC14-8584-4D3B-9F18-3BEA36457B48Q36107186-07F86A04-3B80-4882-9EFB-7A8C0F2077D9Q36457208-10351775-E3CE-466A-91A7-F760BEC7B861Q36678666-168E728E-EC43-42A2-B9D1-F0D5C210D229Q36785137-D6CB4F2F-BC9B-4D20-B4F4-266EB406DA63Q37157248-69771A96-262D-4667-8BAF-09A343257885Q37172093-829AFD48-0E72-4A3B-9B5A-95EECA212707Q37394193-19711434-A722-4DB7-B8C7-B00C12862BE0Q37478003-C75E18D8-FD11-49F4-9D18-FA2EDDC07806Q37696357-8ED7E577-16F4-4143-8E34-0CDE873531B6
P2860
Engineered knottin peptides: a new class of agents for imaging integrin expression in living subjects.
description
2009 nî lūn-bûn
@nan
2009 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մարտին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Engineered knottin peptides: a ...... expression in living subjects.
@ast
Engineered knottin peptides: a ...... expression in living subjects.
@en
type
label
Engineered knottin peptides: a ...... expression in living subjects.
@ast
Engineered knottin peptides: a ...... expression in living subjects.
@en
prefLabel
Engineered knottin peptides: a ...... expression in living subjects.
@ast
Engineered knottin peptides: a ...... expression in living subjects.
@en
P2093
P2860
P1433
P1476
Engineered knottin peptides: a ...... expression in living subjects.
@en
P2093
Jennifer R Cochran
Richard H Kimura
Sanjiv Sam Gambhir
Zhen Cheng
P2860
P304
P356
10.1158/0008-5472.CAN-08-2495
P407
P577
2009-03-10T00:00:00Z