Glucocorticoid-mediated repression of nuclear factor-kappaB-dependent transcription involves direct interference with transactivation - Wikidata - wikimedia - TriplyDB

Glucocorticoid-mediated repression of nuclear factor-kappaB-dependent transcription involves direct interference with transactivation

Glucocorticoid-mediated repression of nuclear factor-kappaB-dependent transcription involves direct interference with transactivation

http://www.wikidata.org/entity/Q33708904

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Transcriptional activation of the NF-kappaB p65 subunit by mitogen- and stress-activated protein kinase-1 (MSK1)Steroid receptor coactivator-1 interacts with the p50 subunit and coactivates nuclear factor kappaB-mediated transactivations Transactivation by the p65 subunit of NF-kappaB in response to interleukin-1 (IL-1) involves MyD88, IL-1 receptor-associated kinase 1, TRAF-6, and Rac1 Mixed-lineage kinase 3 delivers CD3/CD28-derived signals into the IkappaB kinase complex The glucocorticoid receptor inhibits NFkappaB by interfering with serine-2 phosphorylation of the RNA polymerase II carboxy-terminal domain Therapeutic potential of inhibition of the NF-kappaB pathway in the treatment of inflammation and cancer Is there a role for glucocorticoid receptor beta in asthma?Therapeutic effects of acetylsalicylic acid in giant cell arteritis Progesterone prevents traumatic brain injury-induced intestinal nuclear factor kappa B activation and proinflammatory cytokines expression in male rats Compound A, a selective glucocorticoid receptor modulator, enhances heat shock protein Hsp70 gene promoter activation Effusanin E suppresses nasopharyngeal carcinoma cell growth by inhibiting NF-κB and COX-2 signaling Exposure to stressors during juvenility disrupts development-related alterations in the PSA-NCAM to NCAM expression ratio: potential relevance for mood and anxiety disorders Crosstalk in inflammation: the interplay of glucocorticoid receptor-based mechanisms and kinases and phosphatases Minireview: Glucocorticoids in autoimmunity: unexpected targets and mechanisms.Antiinflammatory properties of a plant-derived nonsteroidal, dissociated glucocorticoid receptor modulator in experimental autoimmune encephalomyelitis.Diverse agents act at multiple levels to inhibit the Rel/NF-kappaB signal transduction pathway.How the blood talks to the brain parenchyma and the paraventricular nucleus of the hypothalamus during systemic inflammatory and infectious stimuli.The cysteine-rich region of respiratory syncytial virus attachment protein inhibits innate immunity elicited by the virus and endotoxin S-Adenosyl-L-methionine ameliorates TNFalpha-induced insulin resistance in 3T3-L1 adipocytes.Molecular mechanisms of glucocorticoid action: what is important?Distinct glucocorticoid receptor transcriptional regulatory surfaces mediate the cytotoxic and cytostatic effects of glucocorticoids Novel mechanism of steroid action in skin through glucocorticoid receptor monomers.Dexamethasone restrains ongoing expression of interleukin-23p19 in peripheral blood-derived human macrophages.A fully dissociated compound of plant origin for inflammatory gene repression Cross-talk between glucocorticoid receptor and AP-1.Transcription factor-mediated molecular mechanisms involved in the functional cross-talk between cytokines and glucocorticoids.NCX-1015, a nitric-oxide derivative of prednisolone, enhances regulatory T cells in the lamina propria and protects against 2,4,6-trinitrobenzene sulfonic acid-induced colitis in mice.Dexamethasone-induced oxidative stress enhances myeloma cell radiosensitization while sparing normal bone marrow hematopoiesis Withaferin a strongly elicits IkappaB kinase beta hyperphosphorylation concomitant with potent inhibition of its kinase activity.Glucocorticoid-independent repression of tumor necrosis factor (TNF) alpha-stimulated interleukin (IL)-6 expression by the glucocorticoid receptor: a potential mechanism for protection against an excessive inflammatory response.Peptide-based inhibition of NF-κB rescues diaphragm muscle contractile dysfunction in a murine model of Duchenne muscular dystrophy.Glucocorticoid resistance in childhood leukaemia: mechanisms and modulation.Inhibition of IL-2-induced Jak-STAT signaling by glucocorticoids.Cell specific effects of glucocorticoid treatment on the NF-kappaBp65/IkappaBalpha system in patients with Crohn's disease Glucocorticoids repress NF-kappaB-driven genes by disturbing the interaction of p65 with the basal transcription machinery, irrespective of coactivator levels in the cell Production of interleukin-6 by synovial fibroblasts in rheumatoid arthritis.Stress, cognitive impairment and cell adhesion molecules.Molecular mechanisms of glucocorticoids in the control of inflammation and lymphocyte apoptosis.Glucocorticoids for human skin: new aspects of the mechanism of action.New and improved glucocorticoid receptor ligands.

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Glucocorticoid-mediated repression of nuclear factor-kappaB-dependent transcription involves direct interference with transactivation

http://www.wikidata.org/entity/Q33708904

description

1997 nî lūn-bûn

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1997 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

1997 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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1997年の論文

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1997年論文

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1997年論文

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1997年論文

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1997年論文

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1997年論文

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1997年论文

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name

Glucocorticoid-mediated repres ...... erference with transactivation

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Glucocorticoid-mediated repres ...... erference with transactivation

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Glucocorticoid-mediated repres ...... erference with transactivation

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Glucocorticoid-mediated repres ...... erference with transactivation

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Glucocorticoid-mediated repres ...... erference with transactivation

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Glucocorticoid-mediated repres ...... erference with transactivation

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Proceedings of the National Academy of Sciences of the United States of America

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Glucocorticoid-mediated repres ...... erference with transactivation

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G Haegeman

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K De Bosscher

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M L Schmitz

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S Plaisance

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W Fiers

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W Vanden Berghe

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P2860

The NF-kappa B and I kappa B proteins: new discoveries and insights

Physical association and functional antagonism between the p65 subunit of transcription factor NF-kappa B and the glucocorticoid receptor

The p65 subunit is responsible for the strong transcription activating potential of NF-kappa B

CREB-binding protein/p300 are transcriptional coactivators of p65

Interleukin-6 induction by tumor necrosis factor and interleukin-1 in human fibroblasts involves activation of a nuclear factor binding to a kappa B-like sequence

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

A new technique for the assay of infectivity of human adenovirus 5 DNA

Functional interactions between Stat5 and the glucocorticoid receptor

Negative cross-talk between RelA and the glucocorticoid receptor: a possible mechanism for the antiinflammatory action of glucocorticoids

Interaction of the COOH-terminal transactivation domain of p65 NF-kappa B with TATA-binding protein, transcription factor IIB, and coactivators

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