Optimization of skin electroporation in mice to increase tolerability of DNA vaccine delivery to patients. - Wikidata - wikimedia - TriplyDB

Optimization of skin electroporation in mice to increase tolerability of DNA vaccine delivery to patients.

Optimization of skin electroporation in mice to increase tolerability of DNA vaccine delivery to patients.

http://www.wikidata.org/entity/Q33714027

about

Intradermal electroporation of naked replicon RNA elicits strong immune responses Consensus HIV-1 FSU-A integrase gene variants electroporated into mice induce polyfunctional antigen-specific CD4+ and CD8+ T cells DNA vaccine that targets hemagglutinin to MHC class II molecules rapidly induces antibody-mediated protection against influenza.Optimization of electroporation-enhanced intradermal delivery of DNA vaccine using a minimally invasive surface device.Interference of retroviral envelope with vaccine-induced CD8+ T cell responses is relieved by co-administration of cytokine-encoding vectors.Therapeutic HPV DNA vaccines.DNA vaccination by intradermal electroporation induces long-lasting immune responses in rhesus macaques.Heterodimeric barnase-barstar vaccine molecules: influence of one versus two targeting units specific for antigen presenting cells.Evaluation of delivery conditions for cutaneous plasmid electrotransfer using a multielectrode array.Electro-gene transfer to skin using a noninvasive multielectrode array.A 6K-deletion variant of salmonid alphavirus is non-viable but can be rescued through RNA recombination.Safety and tolerability of the Easy Vax™ clinical epidermal electroporation system in healthy adults.Muscle gene electrotransfer is increased by the antioxidant tempol in mice Superior induction of T cell responses to conserved HIV-1 regions by electroporated alphavirus replicon DNA compared to that with conventional plasmid DNA vaccine.Microneedles for drug and vaccine delivery Electrotransfer parameters as a tool for controlled and targeted gene expression in skin The specificity of targeted vaccines for APC surface molecules influences the immune response phenotype.Antigen Targeting to Human HLA Class II Molecules Increases Efficacy of DNA Vaccination.A pliable electroporation patch (ep-Patch) for efficient delivery of nucleic acid molecules into animal tissues with irregular surface shapes.Oxidative stress induced by HIV-1 reverse transcriptase modulates the enzyme's performance in gene immunization.Evaluation of immunogen delivery by DNA immunization using non-invasive bioluminescence imaging Skin Transfection Patterns and Expression Kinetics of Electroporation-Enhanced Plasmid Delivery Using the CELLECTRA-3P, a Portable Next-Generation Dermal Electroporation Device Fusion to the Lysosome Targeting Signal of the Invariant Chain Alters the Processing and Enhances the Immunogenicity of HIV-1 Reverse Transcriptase Electroporation for DNA immunization: clinical application.Intradermal naked plasmid DNA immunization: mechanisms of action.Clinical potential of electroporation for gene therapy and DNA vaccine delivery.Immunodominance of adenovirus-derived CD8(+) T cell epitopes interferes with the induction of transgene-specific immunity in adenovirus-based immunization.Fusion to Flaviviral Leader Peptide Targets HIV-1 Reverse Transcriptase for Secretion and Reduces Its Enzymatic Activity and Ability to Induce Oxidative Stress but Has No Major Effects on Its Immunogenic Performance in DNA-Immunized Mice.Tapping the Potential of DNA Delivery with Electroporation for Cancer Immunotherapy.Numerical optimization of gene electrotransfer into muscle tissue.DAI (DLM-1/ZBP1) as a genetic adjuvant for DNA vaccines that promotes effective antitumor CTL immunity.Plasmid DNA vaccination using skin electroporation promotes poly-functional CD4 T-cell responses.Towards electroporation based treatment planning considering electric field induced muscle contractions.NF-κB activation during intradermal DNA vaccination is essential for eliciting tumor protective antigen-specific CTL responses.Codon optimization and improved delivery/immunization regimen enhance the immune response against wild-type and drug-resistant HIV-1 reverse transcriptase, preserving its Th2-polarity.DNA immunization site determines the level of gene expression and the magnitude, but not the type of the induced immune response.

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P2860

Optimization of skin electroporation in mice to increase tolerability of DNA vaccine delivery to patients.

http://www.wikidata.org/entity/Q33714027

description

2009 nî lūn-bûn

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2009 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2009 թվականի հունիսին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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Optimization of skin electropo ...... vaccine delivery to patients.

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Optimization of skin electropo ...... vaccine delivery to patients.

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Optimization of skin electropo ...... vaccine delivery to patients.

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Molecular Therapy

P1476

Optimization of skin electropo ...... vaccine delivery to patients.

@en

P2093

Alan D King

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Anna-Karin Roos

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Derin C Walters

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Fredrik Eriksson

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Pavel Pisa

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P2860

DNA vaccines: protective immunizations by parenteral, mucosal, and gene-gun inoculations

Therapeutic tumor immunity induced by polyimmunization with melanoma antigens gp100 and TRP-2.

Increased DNA vaccine delivery and immunogenicity by electroporation in vivo.

Clinical applications of electrochemotherapy.

The effect of pulse repetition frequency on the uptake into electropermeabilized cells in vitro with possible applications in electrochemotherapy.

Increasing the repetition frequency of electric pulse delivery reduces unpleasant sensations that occur in electrochemotherapy.

Effect of plasmid DNA vaccine design and in vivo electroporation on the resulting vaccine-specific immune responses in rhesus macaques.

Effective treatment of cutaneous and subcutaneous malignant tumours by electrochemotherapy.

Biotechnology and DNA vaccines for aquatic animals.

FVIII gene delivery by muscle electroporation corrects murine hemophilia A.

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1637-1642

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scholarly article

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10.1038/MT.2009.120

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9

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17

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2009-06-16T00:00:00Z

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26297313

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19532140

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electroporation

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2835273

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