Chronic lymphocytic leukemia B cells contain anomalous Lyn tyrosine kinase, a putative contribution to defective apoptosis. - Wikidata - wikimedia - TriplyDB

Chronic lymphocytic leukemia B cells contain anomalous Lyn tyrosine kinase, a putative contribution to defective apoptosis.

Chronic lymphocytic leukemia B cells contain anomalous Lyn tyrosine kinase, a putative contribution to defective apoptosis.

http://www.wikidata.org/entity/Q33714786

about

Dynamic regulation of neutrophil survival through tyrosine phosphorylation or dephosphorylation of caspase-8 Integrin inhibition through Lyn-dependent cross talk from CXCR4 chemokine receptors in normal human CD34+ marrow cells Methylation and silencing of protein tyrosine phosphatase receptor type O in chronic lymphocytic leukemia Regulation of mitochondrial functions by protein phosphorylation and dephosphorylation Ibrutinib (PCI-32765) in chronic lymphocytic leukemia The outcome of B-cell receptor signaling in chronic lymphocytic leukemia: proliferation or anergy B cell receptor pathway in chronic lymphocytic leukemia: specific role of CC-292 Targeting the TAM Receptors in Leukemia Management of chronic lymphocytic leukemia (CLL) in the era of B-cell receptor signal transduction inhibitors B-cell receptor signalling and its crosstalk with other pathways in normal and malignant cells Association of reactive oxygen species-mediated signal transduction with in vitro apoptosis sensitivity in chronic lymphocytic leukemia B cells New mutations in chronic lymphocytic leukemia identified by target enrichment and deep sequencing Phase II study of dasatinib in relapsed or refractory chronic lymphocytic leukemia.Metadherin contribute to BCR signaling in chronic lymphocytic leukemia Anomalous constitutive Src kinase activity promotes B lymphoma survival and growth.Elucidating the CXCL12/CXCR4 signaling network in chronic lymphocytic leukemia through phosphoproteomics analysis Cortactin, another player in the Lyn signaling pathway, is over-expressed and alternatively spliced in leukemic cells from patients with B-cell chronic lymphocytic leukemia SLP76 integrates into the B-cell receptor signaling cascade in chronic lymphocytic leukemia cells and is associated with an aggressive disease course Lyn kinase and ZAP70 are substrates of PTPROt in B-cells: Lyn inactivation by PTPROt sensitizes leukemia cells to VEGF-R inhibitor pazopanib Bruton tyrosine kinase represents a promising therapeutic target for treatment of chronic lymphocytic leukemia and is effectively targeted by PCI-32765.Exploiting biological diversity and genomic aberrations in chronic lymphocytic leukemia.Protein kinases: emerging therapeutic targets in chronic lymphocytic leukemia.Human remyelination promoting antibody inhibits apoptotic signaling and differentiation through Lyn kinase in primary rat oligodendrocytes.Kinase pathway dependence in primary human leukemias determined by rapid inhibitor screening.HS1, a Lyn kinase substrate, is abnormally expressed in B-chronic lymphocytic leukemia and correlates with response to fludarabine-based regimen Phospho-specific flow cytometry identifies aberrant signaling in indolent B-cell lymphoma The novel receptor tyrosine kinase Axl is constitutively active in B-cell chronic lymphocytic leukemia and acts as a docking site of nonreceptor kinases: implications for therapy.Induction of Ca²+-driven apoptosis in chronic lymphocytic leukemia cells by peptide-mediated disruption of Bcl-2-IP3 receptor interaction Inhibitors of BTK and ITK: state of the new drugs for cancer, autoimmunity and inflammatory diseases.Two types of BCR interactions are positively selected during leukemia development in the Eμ-TCL1 transgenic mouse model of CLL.AP-1 elements and TCL1 protein regulate expression of the gene encoding protein tyrosine phosphatase PTPROt in leukemia Lyn kinase promotes erythroblast expansion and late-stage development.Novel targeted therapies for mantle cell lymphoma Methylprednisolone suppresses the Wnt signaling pathway in chronic lymphocytic leukemia cell line MEC-1 regulated by LEF-1 expression The phosphoinositide 3-kinase signaling pathway in normal and malignant B cells: activation mechanisms, regulation and impact on cellular functions.The B-cell receptor signaling pathway as a therapeutic target in CLL.Inhibitors of SRC kinases impair antitumor activity of anti-CD20 monoclonal antibodies.Functions of the Lyn tyrosine kinase in health and disease Novel Agents and Emerging Strategies for Targeting the B-Cell Receptor Pathway in CLL Expression and function of the TL1A/DR3 axis in chronic lymphocytic leukemia.

P2860

Q24303939-DE402DCF-4771-4436-8AFE-AE348B22B2D8 Q24304138-9576CBBF-897E-48C3-9004-A70BE57B86BF Q24619893-C723DC66-316F-40A6-A43E-DC3BFB371D39 Q26752880-915BEA8E-EC39-4C99-B0BC-F75BC01E4E82 Q26852328-12B3DB03-07AE-46C0-AF03-6D021EE3A0F3 Q26865760-B73A3E5F-9D72-47FD-8891-4750626E88D6 Q27009550-17E9F0DA-07FB-4E90-90DE-2FC95C5D6D55 Q28078654-E5DEC136-E38C-4503-B756-EDD8A3D07778 Q28081162-69765A33-819E-4D65-9A32-C42D056A2F1E Q28245018-700218C5-D175-4E74-9484-4E6B706A7340 Q28744086-863EB58D-ED9E-489B-B2BA-F69E8B076A51 Q30466798-BD73AFAB-7C4F-49E6-982D-688D22F4FDE6 Q33394487-7A532FD0-DDFE-4265-97FE-D97DD0E650C7 Q33583000-68C2909A-9761-4802-9250-396CCD19E9E1 Q33623874-11C9DEFC-77AD-47B9-AB0E-A8A922BA3429 Q33641404-0F1B83AE-D441-4F96-A8B7-3E65F7E7EBEA Q33695977-96ACDE34-1512-4642-83EF-0EA82B271067 Q33822016-83775B8A-9686-4F8D-BEBC-4294D3AC7114 Q33952692-07BED267-83C4-4612-A100-A4AA03619922 Q34026194-659C9C4D-B8B7-4607-BA73-0B851A752D73 Q34056568-C48750D0-5763-4F79-98E0-4D9D6E500C81 Q34081881-D98A4DE7-6022-4950-8CF6-F141B8AF0FE5 Q34257120-E037AD35-2F2C-4E48-80AD-ED544916C47A Q34307423-5B167841-57D7-4298-B381-3357377F839D Q34328391-AF66E415-AFB4-4B41-A5AA-81C35C0C8B24 Q34448586-CB21B74B-7DFB-4BDD-8392-0464EBFFAFC1 Q34667753-47A51B86-4C2A-4C3F-A477-51330B6D37FF Q34707190-0CBB7F88-7952-4189-9CC9-98162BC9D9AE Q34722000-0F325CBA-FF06-4E5F-A437-820736D284BE Q35153215-4156C1DD-020E-41B5-960D-78F69DA20AB0 Q35604063-E05A4309-6766-485E-9AC0-782318D74F32 Q35848989-6D3ACD49-C381-46AB-9C4C-22DCD521DA46 Q35889841-C1B4294B-ADBD-4DCE-9141-15326B36BEA1 Q36014206-DF1D82CA-0105-40EB-B58D-7C6D751F1447 Q36150234-CA410A10-307B-4887-A138-F6954108C7F1 Q36163034-83763073-31C2-4D78-AD18-E515CD857387 Q36213094-9C44B80A-E7A8-4BBD-B291-4840D6B6E66C Q36299576-43E799C7-120E-449A-B31A-19403CB37D20 Q36404778-AE5CFD24-A9F5-4624-9D09-0F103AE0D5C5 Q36544769-0825B385-3FB6-47BE-B8D5-6587DD04DE18

P2860

Chronic lymphocytic leukemia B cells contain anomalous Lyn tyrosine kinase, a putative contribution to defective apoptosis.

http://www.wikidata.org/entity/Q33714786

description

2005 nî lūn-bûn

@nan

2005 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2005 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2005年の論文

@ja

2005年論文

@yue

2005年論文

@zh-hant

2005年論文

@zh-hk

2005年論文

@zh-mo

2005年論文

@zh-tw

2005年论文

@wuu

name

Chronic lymphocytic leukemia B ...... bution to defective apoptosis.

@ast

Chronic lymphocytic leukemia B ...... bution to defective apoptosis.

@en

type

label

Chronic lymphocytic leukemia B ...... bution to defective apoptosis.

@ast

Chronic lymphocytic leukemia B ...... bution to defective apoptosis.

@en

prefLabel

Chronic lymphocytic leukemia B ...... bution to defective apoptosis.

@ast

Chronic lymphocytic leukemia B ...... bution to defective apoptosis.

@en

P1433

Q33714786-DF044E12-5BD3-4BFC-A2EF-03D3E89364D5

P1476

Q33714786-CF2FA0C8-329E-4C9A-8B5E-4A08A5B615B1

P2093

Q33714786-290A7E6E-F279-4705-A48E-83944882F113

Q33714786-334DDE65-08E8-4029-AB0C-EBE604161076

Q33714786-5C549400-B976-4B7B-BB32-263E0483DDBA

Q33714786-959E5C26-06C3-48BE-AD3A-6591D8E46362

Q33714786-A780C3BC-2868-451B-81A8-F3DCE01C5D06

Q33714786-AEC1F668-C950-4BDB-8540-5D2F098CA74D

Q33714786-AEC5BF12-05E7-4837-BC28-0007C06C767B

Q33714786-B26D99BE-247F-4967-96D5-54FE68750416

Q33714786-C063316B-ECBD-41C0-B523-82B5DA91D41F

Q33714786-E636C0CF-D5EA-4D71-9A5F-8EFAA26105CE

P2860

Q33714786-0A452712-0D3C-4016-9851-3D62859E256C

Q33714786-0B8703B6-2F28-49F3-BAD4-CD3F483C22B2

Q33714786-0CBFFB8C-76A2-4C56-8186-D863A9065977

Q33714786-12E015FA-0980-4EA4-BA36-3C6D7BA3BEBA

Q33714786-1394959C-08F2-4C8E-BE8F-94E66CDBE924

Q33714786-1B8959BE-FD05-4E53-8219-5E08EAC79CF5

Q33714786-1D30A160-23F1-4EA1-B667-1F2A3BB3E921

Q33714786-1E1688F6-5599-4BAA-BEAB-4D5AA5436F57

Q33714786-1F58727C-8940-4128-B083-D90EB30EED0D

Q33714786-212F2C19-D163-4D61-9845-B7FE3D0A6019

P304

Q33714786-DCC252BC-7EDE-40BC-84AB-E071226E6147

P31

Q33714786-60EB31F8-84EB-4676-B472-786FC4CC8FF6

P356

Q33714786-5F250456-96DE-4C76-9FB7-7D697DC19E4B

P407

Q33714786-0F6DD3AD-0316-4B4F-A135-DE8CAE97AE1D

P433

Q33714786-167752D9-D1A1-4CCB-BAFA-1BB822A8885B

P478

Q33714786-FDAC7261-3053-4C2B-A318-1E2C43D8CE68

P577

Q33714786-233ECD4E-8A6D-4B8C-A932-ED51F5D6F817

P698

Q33714786-24C7CB92-388B-4F80-93B1-D670CE94C5A6

P921

Q33714786-01F3B149-B71B-4A04-AB4A-A436C58CDBC5

Q33714786-24DA663D-967A-4B07-A9F7-7C60EAF58200

P932

Q33714786-384D6343-203E-422A-8E60-14B1CB219D78

P356

P1433

Journal of Clinical Investigation

P1476

Chronic lymphocytic leukemia B ...... bution to defective apoptosis.

@en

P2093

Anna Cabrelle

http://www.w3.org/2001/XMLSchema#string

Anna Maria Brunati

http://www.w3.org/2001/XMLSchema#string

Antonella Contri

http://www.w3.org/2001/XMLSchema#string

Arianna Donella-Deana

http://www.w3.org/2001/XMLSchema#string

Gianpietro Semenzato

http://www.w3.org/2001/XMLSchema#string

Livio Trentin

http://www.w3.org/2001/XMLSchema#string

Lorenzo A Pinna

http://www.w3.org/2001/XMLSchema#string

Luca Cesaro

http://www.w3.org/2001/XMLSchema#string

Marta Miorin

http://www.w3.org/2001/XMLSchema#string

Renato Zambello

http://www.w3.org/2001/XMLSchema#string

P2860

Three-dimensional structure of the tyrosine kinase c-Src

Inhibition of the transforming activity of FLT3 internal tandem duplication mutants from AML patients by a tyrosine kinase inhibitor.

Essential role of Src-family protein tyrosine kinases in NF-kappaB activation during B cell development

Activation of Src-like p56/p53lyn tyrosine kinase by ionizing radiation

A revised European-American classification of lymphoid neoplasms: a proposal from the International Lymphoma Study Group

Rational design and synthesis of a novel anti-leukemic agent targeting Bruton's tyrosine kinase (BTK), LFM-A13 [alpha-cyano-beta-hydroxy-beta-methyl-N-(2, 5-dibromophenyl)propenamide]

Functions of lipid rafts in biological membranes

The specificities of protein kinase inhibitors: an update

Activation of the Src-family tyrosine kinase Hck by SH3 domain displacement

Visualizing lipid raft dynamics and early signaling events during antigen receptor-mediated B-lymphocyte activation.

P304

369-378

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1172/JCI200522094

http://www.w3.org/2001/XMLSchema#string

P407

P433

2

http://www.w3.org/2001/XMLSchema#string

P478

115

http://www.w3.org/2001/XMLSchema#string

P577

2005-02-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

15650771

http://www.w3.org/2001/XMLSchema#string

P921

P932

544036

http://www.w3.org/2001/XMLSchema#string