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The role of epigenetic transcription repression and DNA methyltransferases in cancer.

The role of epigenetic transcription repression and DNA methyltransferases in cancer.

http://www.wikidata.org/entity/Q33718270

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The Role of Sulforaphane in Epigenetic Mechanisms, Including Interdependence between Histone Modification and DNA Methylation Sirtuin-dependent epigenetic regulation in the maintenance of genome integrity Computer-aided Molecular Design of Compounds Targeting Histone Modifying Enzymes Epigenetic Alterations in Parathyroid Cancers Modulation of epigenetic targets for anticancer therapy: clinicopathological relevance, structural data and drug discovery perspectives Designing a broad-spectrum integrative approach for cancer prevention and treatment.Promoter methylation status of the tumor suppressor genes p16 and cadherin 1 in cervical intraepithelial neoplasia DNA methyltransferase3a expression is an independent poor prognostic indicator in gastric cancer.HBx induces hypomethylation of distal intragenic CpG islands required for active expression of developmental regulators Epigenetic modulation of intestinal cholesterol transporter Niemann-Pick C1-like 1 (NPC1L1) gene expression by DNA methylation.A global view of the oncogenic landscape in nasopharyngeal carcinoma: an integrated analysis at the genetic and expression levels.Laccaic acid A is a direct, DNA-competitive inhibitor of DNA methyltransferase 1.Clinical application of genetics in management of colorectal cancer.An ultrasensitive high throughput screen for DNA methyltransferase 1-targeted molecular probes Kaiso interacts with p120-catenin to regulate β-catenin expression at the transcriptional level.Epigenetic silencing of TFPI-2 in canine diffuse large B-cell lymphoma Overexpression of mutant Ptch in rhabdomyosarcomas is associated with promoter hypomethylation and increased Gli1 and H3K4me3 occupancy.Immunohistochemical expression of DNA methyltransferases 1, 3a, and 3b in actinic cheilitis and lip squamous cell carcinomas.Attenuation of miR-17∼92 Cluster in Bronchopulmonary Dysplasia.Genome-wide pharmacologic unmasking identifies tumor suppressive microRNAs in multiple myeloma.Efficacy of decitabine-loaded nanogels in overcoming cancer drug resistance is mediated via sustained DNA methyltransferase 1 (DNMT1) depletion.DNA methylation of specific CpG sites in the promoter region regulates the transcription of the mouse oxytocin receptor.Unravelling the hidden DNA structural/physical code provides novel insights on promoter location Functional DNA methylation differences between tissues, cell types, and across individuals discovered using the M&M algorithm.Significance of DNMT3b in oral cancer.Selective non-nucleoside inhibitors of human DNA methyltransferases active in cancer including in cancer stem cells.Delivering preventive, predictive and personalised cancer medicine for renal cell carcinoma: the challenge of tumour heterogeneity.Review of the alterations in DNA methylation in esophageal squamous cell carcinoma.Expression of DNMTs and MBD2 in GIST.Role of DNA methylation in cardiovascular diseases.Upregulated expression of miR-106a by DNA hypomethylation plays an oncogenic role in hepatocellular carcinoma.Aberrant promoter methylation of Dab2 gene in myelodysplastic syndrome.Epigenetic-Mediated Downregulation of μ-Protocadherin in Colorectal Tumours.Maternal nicotinamide supplementation causes global DNA hypomethylation, uracil hypo-incorporation and gene expression changes in fetal rats.Epigenetic therapies - a new direction in clinical medicine.

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P2860

The role of epigenetic transcription repression and DNA methyltransferases in cancer.

http://www.wikidata.org/entity/Q33718270

description

2010 nî lūn-bûn

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2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2010 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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The role of epigenetic transcription repression and DNA methyltransferases in cancer.

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The role of epigenetic transcription repression and DNA methyltransferases in cancer.

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The role of epigenetic transcription repression and DNA methyltransferases in cancer

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Fernanda Gonçalves Salum

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Liliane Soares Yurgel

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Maria Antonia Zancanaro de Figueiredo

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P2860

Initial sequencing and analysis of the human genome

The human DNA methyltransferases (DNMTs) 1, 3a and 3b: coordinate mRNA expression in normal tissues and overexpression in tumors

Cloning, expression and chromosome locations of the human DNMT3 gene family

DNA methylation patterns and epigenetic memory

Translating the Histone Code

Epigenetic gene silencing in cancer – a mechanism for early oncogenic pathway addiction?

Human DNA-(Cytosine-5) Methyltransferase-PCNA Complex as a Target for p21WAF1

The retinoblastoma gene product interacts with maintenance human DNA (cytosine-5) methyltransferase and modulates its activity

Specific gene hypomethylation and cancer: new insights into coding region feature trends

Interactions within the mammalian DNA methyltransferase family

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677-687

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10.1002/CNCR.25482

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117

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Filipe Ivan Daniel

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2010-10-13T00:00:00Z

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20945317

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