Leukemia-initiating cells from some acute myeloid leukemia patients with mutated nucleophosmin reside in the CD34(-) fraction.
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Stem Cell Modeling of Core Binding Factor Acute Myeloid LeukemiaHumanized hemato-lymphoid system miceCancer stem cell targeted therapy: progress amid controversies.Genomics-based Approach and Prognostic Stratification Significance of Gene Mutations in Intermediate-risk Acute Myeloid LeukemiaHedgehog Signaling in the Maintenance of Cancer Stem CellsKinase-independent mechanisms of resistance of leukemia stem cells to tyrosine kinase inhibitorsDistribution and levels of cell surface expression of CD33 and CD123 in acute myeloid leukemiaUpdate on acute myeloid leukemia stem cells: New discoveries and therapeutic opportunitiesCancer stem cells in basic science and in translational oncology: can we translate into clinical application?Life history trade-offs in cancer evolutionTumour heterogeneity and cancer cell plasticityTranslating leukemia stem cells into the clinical setting: Harmonizing the heterogeneity.Data-Driven Phenotypic Dissection of AML Reveals Progenitor-like Cells that Correlate with Prognosis.Acute myeloid leukemia does not deplete normal hematopoietic stem cells but induces cytopenias by impeding their differentiationTargeting the phosphoinositide 3-kinase pathway in hematologic malignanciesSox4 is a key oncogenic target in C/EBPα mutant acute myeloid leukemiaClonal evolution of preleukemic hematopoietic stem cells precedes human acute myeloid leukemia.The therapeutic implications of plasticity of the cancer stem cell phenotype.Expression of the cytoplasmic NPM1 mutant (NPMc+) causes the expansion of hematopoietic cells in zebrafish.Association of a leukemic stem cell gene expression signature with clinical outcomes in acute myeloid leukemia.Heterogeneity of clonal expansion and maturation-linked mutation acquisition in hematopoietic progenitors in human acute myeloid leukemia.Two hits are better than one: targeting both phosphatidylinositol 3-kinase and mammalian target of rapamycin as a therapeutic strategy for acute leukemia treatment.From single cells to deep phenotypes in cancer.The mammary cellular hierarchy and breast cancer.Human acute myelogenous leukemia stem cells are rare and heterogeneous when assayed in NOD/SCID/IL2Rγc-deficient mice.Prospective separation of normal and leukemic stem cells based on differential expression of TIM3, a human acute myeloid leukemia stem cell markerHeterogeneous sensitivity of human acute myeloid leukemia to β-catenin down-modulation.Proteomic profiling identifies distinct protein patterns in acute myelogenous leukemia CD34+CD38- stem-like cells.Single-cell mass cytometry reveals intracellular survival/proliferative signaling in FLT3-ITD-mutated AML stem/progenitor cells.Prognostic value of monitoring a candidate immunophenotypic leukaemic stem/progenitor cell population in patients allografted for acute myeloid leukaemia.Establishment of a humanized APL model via the transplantation of PML-RARA-transduced human common myeloid progenitors into immunodeficient mice.Human cancer growth and therapy in immunodeficient mouse models.High levels of CD34+CD38low/-CD123+ blasts are predictive of an adverse outcome in acute myeloid leukemia: a Groupe Ouest-Est des Leucemies Aigues et Maladies du Sang (GOELAMS) study.Cancer stem cells: impact, heterogeneity, and uncertaintyA clinically relevant population of leukemic CD34(+)CD38(-) cells in acute myeloid leukemiaProstate cancer stem cell biology.High-Dimensional Analysis of Acute Myeloid Leukemia Reveals Phenotypic Changes in Persistent Cells during Induction Therapy.Acute myeloid leukemia stem cells and CD33-targeted immunotherapyAlkylator-Induced and Patient-Derived Xenograft Mouse Models of Therapy-Related Myeloid Neoplasms Model Clinical Disease and Suggest the Presence of Multiple Cell Subpopulations with Leukemia Stem Cell ActivityNormal Hematopoietic Progenitor Subsets Have Distinct Reactive Oxygen Species, BCL2 and Cell-Cycle Profiles That Are Decoupled from Maturation in Acute Myeloid Leukemia
P2860
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P2860
Leukemia-initiating cells from some acute myeloid leukemia patients with mutated nucleophosmin reside in the CD34(-) fraction.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Leukemia-initiating cells from ...... eside in the CD34(-) fraction.
@ast
Leukemia-initiating cells from ...... eside in the CD34(-) fraction.
@en
type
label
Leukemia-initiating cells from ...... eside in the CD34(-) fraction.
@ast
Leukemia-initiating cells from ...... eside in the CD34(-) fraction.
@en
prefLabel
Leukemia-initiating cells from ...... eside in the CD34(-) fraction.
@ast
Leukemia-initiating cells from ...... eside in the CD34(-) fraction.
@en
P2093
P2860
P1433
P1476
Leukemia-initiating cells from ...... eside in the CD34(-) fraction.
@en
P2093
David C Taussig
Debra Lillington
Dominique Bonnet
Farideh Miraki-Moud
Heather Oakervee
Jacques Vargaftig
Jamie Cavenagh
John G Gribben
Kirsty Sharrock
Samir G Agrawal
P2860
P304
P356
10.1182/BLOOD-2009-02-206565
P407
P577
2010-01-06T00:00:00Z