Reduced insulin/IGF-1 signaling restores germ cell immortality to Caenorhabditis elegans Piwi mutants
about
Caenorhabditis elegans RSD-2 and RSD-6 promote germ cell immortality by maintaining small interfering RNA populationsComplex coding of endogenous siRNA, transcriptional silencing and H3K9 methylation on native targets of germline nuclear RNAi in C. elegans.Ancient and novel small RNA pathways compensate for the loss of piRNAs in multiple independent nematode lineages.Lack of pairing during meiosis triggers multigenerational transgene silencing in Caenorhabditis elegans.piRNAs and piRNA-Dependent siRNAs Protect Conserved and Essential C. elegans Genes from Misrouting into the RNAi PathwayEpigenetic regulation of ageing: linking environmental inputs to genomic stability.Mutation of C. elegans demethylase spr-5 extends transgenerational longevityThe RNase PARN-1 Trims piRNA 3' Ends to Promote Transcriptome Surveillance in C. elegans.Natural RNA interference directs a heritable response to the environment.Specific down-regulation of spermatogenesis genes targeted by 22G RNAs in hybrid sterile males associated with an X-Chromosome introgressionEnvironmental stresses induce transgenerationally inheritable survival advantages via germline-to-soma communication in Caenorhabditis elegans.Transgenerational inheritance: Models and mechanisms of non-DNA sequence-based inheritance.The soft genome.The Helicase Aquarius/EMB-4 Is Required to Overcome Intronic Barriers to Allow Nuclear RNAi Pathways to Heritably Silence Transcription.Repressive Chromatin in Caenorhabditis elegans: Establishment, Composition, and Function.A Sex Chromosome piRNA Promotes Robust Dosage Compensation and Sex Determination in C. elegans.Identification of piRNA Binding Sites Reveals the Argonaute Regulatory Landscape of the C. elegans Germline.A Neuronal piRNA Pathway Inhibits Axon Regeneration in C. elegans.The RNAi Inheritance Machinery of Caenorhabditis elegans.Transgenerational Sterility of Piwi Mutants Represents a Dynamic Form of Adult Reproductive Diapause.The piRNA pathway responds to environmental signals to establish intergenerational adaptation to stress
P2860
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P2860
Reduced insulin/IGF-1 signaling restores germ cell immortality to Caenorhabditis elegans Piwi mutants
description
2014 nî lūn-bûn
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2014 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2014年の論文
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2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Reduced insulin/IGF-1 signalin ...... rhabditis elegans Piwi mutants
@ast
Reduced insulin/IGF-1 signalin ...... rhabditis elegans Piwi mutants
@en
type
label
Reduced insulin/IGF-1 signalin ...... rhabditis elegans Piwi mutants
@ast
Reduced insulin/IGF-1 signalin ...... rhabditis elegans Piwi mutants
@en
prefLabel
Reduced insulin/IGF-1 signalin ...... rhabditis elegans Piwi mutants
@ast
Reduced insulin/IGF-1 signalin ...... rhabditis elegans Piwi mutants
@en
P2093
P2860
P50
P1433
P1476
Reduced insulin/IGF-1 signalin ...... rhabditis elegans Piwi mutants
@en
P2093
Aisa Sakaguchi
Jacinth Mitchell
Kohta Ikegami
Leonard D Goldstein
Matt Simon
Shawn Ahmed
P2860
P304
P356
10.1016/J.CELREP.2014.03.056
P577
2014-04-24T00:00:00Z