Balancing selection maintains a form of ERAP2 that undergoes nonsense-mediated decay and affects antigen presentation. - Wikidata - wikimedia - TriplyDB

Balancing selection maintains a form of ERAP2 that undergoes nonsense-mediated decay and affects antigen presentation.

Balancing selection maintains a form of ERAP2 that undergoes nonsense-mediated decay and affects antigen presentation.

http://www.wikidata.org/entity/Q33728652

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Fetal ERAP2 variation is associated with preeclampsia in African Americans in a case-control study RNA sequencing reveals the role of splicing polymorphisms in regulating human gene expression Genetic variation of pre-mRNA alternative splicing in human populations A Common Single Nucleotide Polymorphism in Endoplasmic Reticulum Aminopeptidase 2 Induces a Specificity Switch That Leads to Altered Antigen Processing Understanding rare and common diseases in the context of human evolution A genome-wide association study identifies a functional ERAP2 haplotype associated with birdshot chorioretinopathy Exome sequencing in sporadic autism spectrum disorders identifies severe de novo mutations Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis.Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity.GLiMMPS: robust statistical model for regulatory variation of alternative splicing using RNA-seq data.Natural Selection in the Great Apes Impact of past climatic changes and resource availability on the population demography of three food-specialist bees.Recommendations for Accurate Resolution of Gene and Isoform Allele-Specific Expression in RNA-Seq Data.Identification of a myometrial molecular profile for dystocic labor.Ancestral components of admixed genomes in a Mexican cohort.The genetic basis of ankylosing spondylitis: new insights into disease pathogenesis Genetic adaptation of the antibacterial human innate immunity network Signatures of environmental genetic adaptation pinpoint pathogens as the main selective pressure through human evolution.Genetics of gene expression in primary immune cells identifies cell type-specific master regulators and roles of HLA alleles.Selection on a variant associated with improved viral clearance drives local, adaptive pseudogenization of interferon lambda 4 (IFNL4)Balancing selection on a regulatory region exhibiting ancient variation that predates human-neandertal divergence A role for naturally occurring alleles of endoplasmic reticulum aminopeptidases in tumor immunity and cancer pre-disposition.Leprosy association with low MASP-2 levels generated by MASP2 haplotypes and polymorphisms flanking MAp19 exon 5 An evolutionary analysis of antigen processing and presentation across different timescales reveals pervasive selection.A signature of balancing selection in the region upstream to the human UGT2B4 gene and implications for breast cancer risk.Endoplasmic reticulum aminopeptidase 1 and rheumatic disease: functional variation.ERAP2 is associated with ankylosing spondylitis in HLA-B27-positive and HLA-B27-negative patients A general population genetic framework for antagonistic selection that accounts for demography and recurrent mutation Allele-Independent Turnover of Human Leukocyte Antigen (HLA) Class Ia Molecules Role of endoplasmic reticulum aminopeptidases in health and disease: from infection to cancer.The psoriasis-associated deletion of late cornified envelope genes LCE3B and LCE3C has been maintained under balancing selection since Human Denisovan divergence.ERAP1 and ERAP2 Gene Variations Influence the Risk of Psoriatic Arthritis in Romanian Population.Structural Basis for Antigenic Peptide Recognition and Processing by Endoplasmic Reticulum (ER) Aminopeptidase 2 Proteasomes, TAP, and endoplasmic reticulum-associated aminopeptidase associated with antigen processing control CD4+ Th cell responses by regulating indirect presentation of MHC class II-restricted cytoplasmic antigens Reproduction and immunity-driven natural selection in the human WFDC locus.Recent Selection Changes in Human Genes under Long-Term Balancing Selection.A Novel ERAP2 Haplotype Structure in a Chilean Population: Implications for ERAP2 Protein Expression and Preeclampsia Risk.Y chromosome haplogroups based genome-wide association study pinpoints revelation for interactions on non-obstructive azoospermia Sequence diversity of Pan troglodytes subspecies and the impact of WFDC6 selective constraints in reproductive immunity

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Balancing selection maintains a form of ERAP2 that undergoes nonsense-mediated decay and affects antigen presentation.

http://www.wikidata.org/entity/Q33728652

description

2010 nî lūn-bûn

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2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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Balancing selection maintains ...... affects antigen presentation.

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Balancing selection maintains ...... affects antigen presentation.

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JOURNAL.PGEN.1001157

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Balancing selection maintains ...... affects antigen presentation.

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Aida M Andrés

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Andrew G Clark

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Belen Hurle

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Jennifer L Cannons

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Megan Y Dennis

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Pamela L Schwartzberg

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Rasmus Nielsen

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Scott H Williamson

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Shih-Queen Lee-Lin

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Warren W Kretzschmar

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P2860

A mutation in the myostatin gene increases muscle mass and enhances racing performance in heterozygote dogs

Balancing selection of a frame-shift mutation in the MRC2 gene accounts for the outbreak of the Crooked Tail Syndrome in Belgian Blue Cattle

Inferring the joint demographic history of multiple populations from multidimensional SNP frequency data

Localizing recent adaptive evolution in the human genome

BioGPS: an extensible and customizable portal for querying and organizing gene annotation resources.

A map of recent positive selection in the human genome

Ancient human genome sequence of an extinct Palaeo-Eskimo

Evolutionary and Biomedical Insights from the Rhesus Macaque Genome

Initial sequence of the chimpanzee genome and comparison with the human genome

Cystic fibrosis heterozygote resistance to cholera toxin in the cystic fibrosis mouse model

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e1001157

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scholarly article

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10.1371/JOURNAL.PGEN.1001157

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10

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6

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Carlos D. Bustamante

NISC Comparative Sequencing Program

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2010-10-14T00:00:00Z

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47545632

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2954825

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