Myeloperoxidase: an oxidative pathway for generating dysfunctional high-density lipoprotein - Wikidata - wikimedia - TriplyDB

Myeloperoxidase: an oxidative pathway for generating dysfunctional high-density lipoprotein

Myeloperoxidase: an oxidative pathway for generating dysfunctional high-density lipoprotein

http://www.wikidata.org/entity/Q33729198

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Chemistry and biology of reactive oxygen species in signaling or stress responses Are either or both hyperuricemia and xanthine oxidase directly toxic to the vasculature? A critical appraisal Sequence conservation of apolipoprotein A-I affords novel insights into HDL structure-function 3-nitrotyrosine modified proteins in atherosclerosis HDL-apoA-I exchange: rapid detection and association with atherosclerosis The roles of myeloperoxidase in coronary artery disease and its potential implication in plaque rupture.Humans with atherosclerosis have impaired ABCA1 cholesterol efflux and enhanced high-density lipoprotein oxidation by myeloperoxidase.Modifying apolipoprotein A-I by malondialdehyde, but not by an array of other reactive carbonyls, blocks cholesterol efflux by the ABCA1 pathway Exchange of apolipoprotein A-I between lipid-associated and lipid-free states: a potential target for oxidative generation of dysfunctional high density lipoproteins Primary prevention of coronary heart disease: integration of new data, evolving views, revised goals, and role of rosuvastatin in management. A comprehensive survey.Cholesterol efflux and atheroprotection: advancing the concept of reverse cholesterol transport.Apolipoprotein A-II influences apolipoprotein E-linked cardiovascular disease risk in women with high levels of HDL cholesterol and C-reactive protein.Nature-inspired nanoformulations for contrast-enhanced in vivo MR imaging of macrophages.Do free radicals play causal role in atherosclerosis? Low density lipoprotein oxidation and vitamin E revisited.Effects of a novel pharmacologic inhibitor of myeloperoxidase in a mouse atherosclerosis model.Myeloperoxidase: a therapeutic target for preventing insulin resistance and the metabolic sequelae of obesity?Plasminogen activator inhibitor-2 polymorphism associates with recurrent coronary event risk in patients with high HDL and C-reactive protein levels.High-density lipoproteins and coronary artery disease: a single-center cohort study.Biochemical and functional characterization of charge-defined subfractions of high-density lipoprotein from normal adults.HDL from apoA1 transgenic mice expressing the 4WF isoform is resistant to oxidative loss of function Reactive oxygen species in cardiovascular disease.Impact of HDL oxidation by the myeloperoxidase system on sterol efflux by the ABCA1 pathway Thiocyanate supplementation decreases atherosclerotic plaque in mice expressing human myeloperoxidase.Site-specific oxidation of apolipoprotein A-I impairs cholesterol export by ABCA1, a key cardioprotective function of HDL.Myeloperoxidase targets apolipoprotein A-I, the major high density lipoprotein protein, for site-specific oxidation in human atherosclerotic lesions Impact of mifepristone, a glucocorticoid/progesterone antagonist, on HDL cholesterol, HDL particle concentration, and HDL function.Testosterone replacement in hypogonadal men alters the HDL proteome but not HDL cholesterol efflux capacity Reactive Oxygen Species, SUMOylation, and Endothelial Inflammation Serum amyloid A impairs the antiinflammatory properties of HDL Tyrosine-lipid peroxide adducts from radical termination: para coupling and intramolecular Diels-Alder cyclization.Assessing Human Health Risk to Endocrine Disrupting Chemicals: a Focus on Prenatal Exposures and Oxidative Stress Why targeting HDL should work as a therapeutic tool, but has not.The Application of a Modified d-ROMs Test for Measurement of Oxidative Stress and Oxidized High-Density Lipoprotein.The protein cargo of HDL: implications for vascular wall biology and therapeutics.Understanding and applying tyrosine biochemical diversity.Exploring oxidative modifications of tyrosine: an update on mechanisms of formation, advances in analysis and biological consequences.Dysfunctional HDL and atherosclerotic cardiovascular disease.Role of Hypohalous Acids in Basement Membrane Homeostasis.Influence of HDL particles on cell-cholesterol efflux under various pathological conditions.Novel technique for generating macrophage foam cells for in vitro reverse cholesterol transport studies.

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P2860

Myeloperoxidase: an oxidative pathway for generating dysfunctional high-density lipoprotein

http://www.wikidata.org/entity/Q33729198

description

2010 nî lūn-bûn

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2010 թուականի Մարտին հրատարակուած գիտական յօդուած

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2010 թվականի մարտին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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Chemical Research in Toxicology

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Myeloperoxidase: an oxidative ...... ional high-density lipoprotein

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Baohai Shao

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Jay W Heinecke

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John F Oram

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Michael N Oda

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P2860

Oxidants, antioxidants, and the degenerative diseases of aging

Shotgun proteomics implicates protease inhibition and complement activation in the antiinflammatory properties of HDL

Nitric oxide: physiology, pathophysiology, and pharmacology

Crystal structure of truncated human apolipoprotein A-I suggests a lipid-bound conformation

Mass spectrometry-based proteomics

A receptor-mediated pathway for cholesterol homeostasis

A three-dimensional molecular model of lipid-free apolipoprotein A-I determined by cross-linking/mass spectrometry and sequence threading.

Lysine residues direct the chlorination of tyrosines in YXXK motifs of apolipoprotein A-I when hypochlorous acid oxidizes high density lipoprotein.

Neutrophils employ the myeloperoxidase system to generate antimicrobial brominating and chlorinating oxidants during sepsis.

Oxidation of LDL by myeloperoxidase and reactive nitrogen species: reaction pathways and antioxidant protection.

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10.1021/TX9003775

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3

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23

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