Autophagy is a protective mechanism in normal cartilage, and its aging-related loss is linked with cell death and osteoarthritis - Wikidata - wikimedia - TriplyDB

Autophagy is a protective mechanism in normal cartilage, and its aging-related loss is linked with cell death and osteoarthritis

Autophagy is a protective mechanism in normal cartilage, and its aging-related loss is linked with cell death and osteoarthritis

http://www.wikidata.org/entity/Q33729300

about

Cellular ageing mechanisms in osteoarthritis Role of autophagy in megakaryocyte differentiation and platelet formation Chondrocyte Apoptosis in the Pathogenesis of Osteoarthritis Inflammation and intracellular metabolism: new targets in OA Recent insights into the role of autophagy in the pathogenesis of rheumatoid arthritis Biomarkers of Chondrocyte Apoptosis and Autophagy in Osteoarthritis Autophagy in stem cells.Osteoarthritis year 2011 in review: biology Cartilage to bone transitions in health and disease Mitochondria and the autophagy-inflammation-cell death axis in organismal aging The Role of miRNAs in Common Inflammatory Arthropathies: Osteoarthritis and Gouty Arthritis Insights on Molecular Mechanisms of Chondrocytes Death in Osteoarthritis Review: Metabolic Regulation of Inflammation in Osteoarthritis mTOR: a potential therapeutic target in osteoarthritis?Lessons learned from placebo groups in antidepressant trials Increased macroautophagy in the pathological process of intervertebral disc degeneration in rats Bach1 deficiency reduces severity of osteoarthritis through upregulation of heme oxygenase-1 Role of autophagy in the progression of osteoarthritis: The autophagy inhibitor, 3-methyladenine, aggravates the severity of experimental osteoarthritis.Curcumin Inhibits Apoptosis of Chondrocytes through Activation ERK1/2 Signaling Pathways Induced Autophagy.The variability of autophagy and cell death susceptibility: Unanswered questions.MicroRNAs and Autophagy: Fine Players in the Control of Chondrocyte Homeostatic Activities in Osteoarthritis.Downregulation of protein kinase CK2 activity facilitates tumor necrosis factor-α-mediated chondrocyte death through apoptosis and autophagy.Hypoxia, RONS and energy metabolism in articular cartilage.Emerging roles of SUMO modification in arthritis.Loss of Vhl in cartilage accelerated the progression of age-associated and surgically induced murine osteoarthritis Metabolic enrichment of omega-3 polyunsaturated fatty acids does not reduce the onset of idiopathic knee osteoarthritis in mice.Recent progress in histochemistry and cell biology.Mechanical injury suppresses autophagy regulators and pharmacologic activation of autophagy results in chondroprotection.Joint pathology and platelet-rich plasma therapies.Osteoarthritis: a disease of the joint as an organ.The relationship of autophagy defects to cartilage damage during joint aging in a mouse model.Uric acid is a danger signal of increasing risk for osteoarthritis through inflammasome activation FoxO transcription factors support oxidative stress resistance in human chondrocytes SIRT1 protects against apoptosis by promoting autophagy in degenerative human disc nucleus pulposus cells.The evidence and the possible significance of autophagy in degeneration model of human cervical end-plate cartilage.An exploratory analysis of the effects of a weight loss plus exercise program on cellular quality control mechanisms in older overweight women Peroxisome proliferator-activated receptor γ coactivator 1α and FoxO3A mediate chondroprotection by AMP-activated protein kinase.Biomarkers of early stage osteoarthritis, rheumatoid arthritis and musculoskeletal health.IRGM rs13361189 polymorphism may contribute to susceptibility to Crohn's disease: A meta-analysis Autophagy activation and protection from mitochondrial dysfunction in human chondrocytes.

P2860

Q26746549-3A875FCA-9C64-4951-88E2-EBB92EFDB899 Q26749232-9555B163-0EF8-4ABB-8A6B-B084601C7BA9 Q26777068-E7C58EE2-F168-410B-8E68-E49E1E6505AF Q26777620-E4C4938D-D3EE-493C-B9D7-341B7D852D77 Q26784021-F5B5EBEF-0384-42D2-AFA4-6BCAD040EE52 Q26786235-896F3FB7-9D3E-4F9E-B4E5-CA2FB5ADE03A Q26823995-C0F8A195-23A0-40BA-A5AC-A373145D5B03 Q26853546-9C5778A3-1948-40DB-B168-8A8E88EA4F59 Q26865580-46F40DC8-B412-4000-9F0A-7555A095ED5A Q26995343-D2D495F7-0EF3-4F5B-9603-E408CBA7010A Q28068811-8A44DD2A-70D2-431A-8A71-30A62A8D8932 Q28079781-FE596088-9CED-4F7D-B2F5-17B06C85152F Q28079875-93FA42BC-9AEC-4ECC-98F8-87CE3D18C224 Q28087019-7BAA5DAC-3144-44EA-8C8A-2F21DF6D55CD Q28478927-4D46FDF6-9F50-4938-8A50-0E8717B21EE8 Q28581491-33F26422-FB25-41A0-9DE9-DC7754B9B995 Q30401142-7D59E32E-540D-4B48-880C-DEE07DB1496B Q33598969-F6210A0D-D159-43C0-9CB5-B3FD3C521563 Q33617013-DBB755FD-78D0-4F2B-9681-905C83E954A2 Q33631208-EF9D210A-D1DA-49D7-9CE2-05BFC9B52271 Q33872848-092A4BC5-778E-48FC-B967-B8F7D1686B60 Q33895200-E4E6D95A-DD6C-4054-8E47-36B056F4A6F6 Q34088310-D2AAEE5D-E3D6-4A0B-948C-7C71D8A60B86 Q34108064-3DC666DD-FE79-4989-8731-9CD5A2A03F0E Q34115101-6E0A2858-E691-480D-B1A9-8C8CA8955845 Q34115288-07FFA1D5-A10B-4745-893F-2D62130A622E Q34172616-DEA0EA8E-B2D5-43F3-A5BE-08E62CA9CFD7 Q34228180-70D77D69-37E8-41BE-97F6-C89B21E6FFFB Q34240837-EF1600B1-5DC9-40BB-89CF-F8A0CFB47BD2 Q34258870-AE18CBD2-9429-4A93-944B-3282EAB14A91 Q34464179-CB6BB76F-95FB-433B-9C47-F6391C118606 Q34550052-4EA412D1-61E3-4E61-8B31-C6998DA89A7C Q34626746-5FDF4C48-82F0-4858-A474-1316ADE0C085 Q34684132-75087788-42FC-4EA2-A283-39596B0D4622 Q35092545-B7071614-EA4B-4DAF-A568-79236D1C2373 Q35106617-70AB7F4D-AD29-42E1-B0E7-E8593CE9C194 Q35128583-5FCEDC2C-1470-4CBE-9366-F06FA2E2B8CE Q35193733-735BC75C-09FE-495B-9B15-9630010A3668 Q35204220-3AC9D1F3-66AB-4B3E-A135-AD68232572EE Q35236233-038AF9D5-25F7-49EA-9B0B-2E6BE20C4C8B

P2860

Autophagy is a protective mechanism in normal cartilage, and its aging-related loss is linked with cell death and osteoarthritis

http://www.wikidata.org/entity/Q33729300

description

2010 nî lūn-bûn

@nan

2010 թուականի Մարտին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի մարտին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Autophagy is a protective mech ...... cell death and osteoarthritis

@ast

Autophagy is a protective mech ...... cell death and osteoarthritis

@en

type

label

Autophagy is a protective mech ...... cell death and osteoarthritis

@ast

Autophagy is a protective mech ...... cell death and osteoarthritis

@en

prefLabel

Autophagy is a protective mech ...... cell death and osteoarthritis

@ast

Autophagy is a protective mech ...... cell death and osteoarthritis

@en

P1433

Q33729300-6970A642-8220-48A9-A802-ABF1EBA04133

P1476

Q33729300-81AE994A-B106-4AC3-AE15-36F623FD94B4

P2093

Q33729300-14413BD2-78AC-48F3-A23C-120CD532F1CB

Q33729300-2E8AACAC-C3D6-4109-9F78-324C8D59CBD0

Q33729300-435342F3-0713-436C-B565-D4AC8DC9FA1F

Q33729300-EDFCC915-71E1-4448-BB37-039498374BAC

P2860

Q33729300-01BC6EF1-F0E8-415E-9B72-E6EB20CF89F1

Q33729300-0314E113-0A04-4B64-8FB0-D33332B17B62

Q33729300-03B9E068-FC0C-4705-B192-6DAE54A65507

Q33729300-05CD2913-2D49-4D21-8D98-66A33F53E9DE

Q33729300-0D97A854-5884-4021-9B64-37F6CF6EF6AC

Q33729300-0F3C5967-3EE6-4EE0-A684-349F339F5DD8

Q33729300-1966DAFA-9A4F-41EB-86FF-7FDDCDA089A4

Q33729300-1BF71315-9B46-477D-87F7-FF8164CC8209

Q33729300-2479FDEC-9697-4945-8D47-45DA5DAAE692

Q33729300-262FDDDE-0256-48E1-A82E-7FA7C0EDD686

P304

Q33729300-9A58291C-5077-49C3-87B2-36280F935735

P31

Q33729300-DE14BEB1-C870-4F43-AD78-3F3055C43F70

P356

Q33729300-2A684C6E-431C-46A9-897F-8C2464EE7DA8

P433

Q33729300-A832B44E-4AF7-4519-B25A-3871D9990A33

P478

Q33729300-EF2CAAA5-E650-4EAC-838E-913374DBFF39

P50

Q33729300-EDC365EC-0016-4A15-BBCE-0FBB3FCA03DF

P577

Q33729300-42C092C3-4B40-4E03-85E9-7C3D8E37C191

P5875

Q33729300-8F0FD36A-4B53-4FE4-AF14-B8F7D98B9E10

P698

Q33729300-3E7C4D0E-F3F4-4D03-A8AD-91FDA2BB29D0

P921

Q33729300-2FFEB7D5-6139-4B6C-B517-E661F7D9B6D0

Q33729300-BCF815A0-B427-43F9-9D11-C5AAA4D5A935

Q33729300-E0768448-81CF-48FB-B814-B250FFFEB298

P932

Q33729300-04A035EF-FA50-48EC-9248-E6AC2DB46014

P356

P1433

Arthritis and Rheumatism

P1476

Autophagy is a protective mech ...... cell death and osteoarthritis

@en

P2093

Francisco J Blanco

http://www.w3.org/2001/XMLSchema#string

Martin Lotz

http://www.w3.org/2001/XMLSchema#string

Noboru Taniguchi

http://www.w3.org/2001/XMLSchema#string

Shuhei Otsuki

http://www.w3.org/2001/XMLSchema#string

P2860

siRNA screening of the kinome identifies ULK1 as a multidomain modulator of autophagy

Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

Autophagy: molecular machinery for self-eating

Autophagy in the Pathogenesis of Disease

Autophagy fights disease through cellular self-digestion

Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice

Loss of autophagy in the central nervous system causes neurodegeneration in mice

Autophagy and signaling: their role in cell survival and cell death

Regulation of intracellular accumulation of mutant Huntingtin by Beclin 1

P304

791-801

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1002/ART.27305

http://www.w3.org/2001/XMLSchema#string

P433

3

http://www.w3.org/2001/XMLSchema#string

P478

62

http://www.w3.org/2001/XMLSchema#string

P50

P577

2010-03-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

41579782

http://www.w3.org/2001/XMLSchema#string

P698

20187128

http://www.w3.org/2001/XMLSchema#string

P921

P932

2838960

http://www.w3.org/2001/XMLSchema#string