Cell-state transitions regulated by SLUG are critical for tissue regeneration and tumor initiation - Wikidata - wikimedia - TriplyDB

Cell-state transitions regulated by SLUG are critical for tissue regeneration and tumor initiation

Cell-state transitions regulated by SLUG are critical for tissue regeneration and tumor initiation

http://www.wikidata.org/entity/Q33730172

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SLUG is required for SOX9 stabilization and functions to promote cancer stem cells and metastasis in human lung carcinoma Histone demethylase LSD1 controls the phenotypic plasticity of cancer cells SLUG: Critical regulator of epithelial cell identity in breast development and cancer KDM1 class flavin-dependent protein lysine demethylases The WNT-controlled transcriptional regulator LBH is required for mammary stem cell expansion and maintenance of the basal lineage Activation of KRAS promotes the mesenchymal features of basal-type breast cancer.RUNX1, a transcription factor mutated in breast cancer, controls the fate of ER-positive mammary luminal cells.A new role of SNAI2 in postlactational involution of the mammary gland links it to luminal breast cancer development.ΔNp63α Promotes Breast Cancer Cell Motility through the Selective Activation of Components of the Epithelial-to-Mesenchymal Transition Program The origin of breast tumor heterogeneity.Cell Fate Decisions During Breast Cancer Development.The SIRT2 Deacetylase Stabilizes Slug to Control Malignancy of Basal-like Breast Cancer.The C/EBPδ protein is stabilized by estrogen receptor α activity, inhibits SNAI2 expression and associates with good prognosis in breast cancer.Cancer cells exhibit clonal diversity in phenotypic plasticity.Pubertal Mammary Gland Development: Elucidation of In Vivo Morphogenesis Using Murine Models.Conversion to stem-cell state in response to microenvironmental cues is regulated by balance between epithelial and mesenchymal features in lung cancer cells MicroRNA-155-5p is associated with oral squamous cell carcinoma metastasis and poor prognosis.The matricellular protein CCN6 (WISP3) decreases Notch1 and suppresses breast cancer initiating cells.IMP3 promotes stem-like properties in triple-negative breast cancer by regulating SLUG.ΔNp63α induces the expression of FAT2 and Slug to promote tumor invasion.A novel slug-containing negative-feedback loop regulates SCF/c-Kit-mediated hematopoietic stem cell self-renewal.Gremlin-1 is a key regulator of the invasive cell phenotype in mesothelioma.Obesity reversibly depletes the basal cell population and enhances mammary epithelial cell estrogen receptor alpha expression and progenitor activity.Proapoptotic PUMA targets stem-like breast cancer cells to suppress metastasis.Human NUMB6 Induces Epithelial-Mesenchymal Transition and Enhances Breast Cancer Cells Migration and Invasion.EMT programs promote basal mammary stem cell and tumor-initiating cell stemness by inducing primary ciliogenesis and Hedgehog signaling.

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Cell-state transitions regulated by SLUG are critical for tissue regeneration and tumor initiation

http://www.wikidata.org/entity/Q33730172

description

2014 nî lūn-bûn

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2014 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2014 թվականի ապրիլին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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name

Cell-state transitions regulat ...... eneration and tumor initiation

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Cell-state transitions regulat ...... eneration and tumor initiation

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type

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Cell-state transitions regulat ...... eneration and tumor initiation

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Cell-state transitions regulat ...... eneration and tumor initiation

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Cell-state transitions regulat ...... eneration and tumor initiation

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Cell-state transitions regulat ...... eneration and tumor initiation

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J.STEMCR.2014.03.008

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Stem Cell Reports

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Cell-state transitions regulat ...... eneration and tumor initiation

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Adam Skibinski

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Ania Wronski

http://www.w3.org/2001/XMLSchema#string

Charlotte Kuperwasser

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Grace Gill

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Maja Sedic

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Piyush B Gupta

http://www.w3.org/2001/XMLSchema#string

Sarah Phillips

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Sohini Mazumdar

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Stephanie H Shirley

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Theresa Proia

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P2860

Intestinal tumorigenesis initiated by dedifferentiation and acquisition of stem-cell-like properties

Requirement of the histone demethylase LSD1 in Snai1-mediated transcriptional repression during epithelial-mesenchymal transition

Histone demethylation mediated by the nuclear amine oxidase homolog LSD1

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

Stem cells: units of development, units of regeneration, and units in evolution

The snail superfamily of zinc-finger transcription factors

Crypt stem cells as the cells-of-origin of intestinal cancer

The lysine demethylase LSD1 (KDM1) is required for maintenance of global DNA methylation

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633-647

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scholarly article

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10.1016/J.STEMCR.2014.03.008

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5

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2

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Charles M. Perou

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262113725

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