Complementary actions of inhibitors of angiopoietin-2 and VEGF on tumor angiogenesis and growth. - Wikidata - wikimedia - TriplyDB

Complementary actions of inhibitors of angiopoietin-2 and VEGF on tumor angiogenesis and growth.

Complementary actions of inhibitors of angiopoietin-2 and VEGF on tumor angiogenesis and growth.

http://www.wikidata.org/entity/Q33732486

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Methylseleninic acid restricts tumor growth in nude mice model of metastatic breast cancer probably via inhibiting angiopoietin-2 Corneal neovascularization and the utility of topical VEGF inhibition: ranibizumab (Lucentis) vs bevacizumab (Avastin)Profile of trebananib (AMG386) and its potential in the treatment of ovarian cancer Receptor tyrosine kinase-mediated angiogenesis Angiopoietin 2 as a therapeutic target in hepatocellular carcinoma treatment: current perspectives Angiopoietin-Tie signalling in the cardiovascular and lymphatic systems Angiopoietin-2 stimulation of endothelial cells induces alphavbeta3 integrin internalization and degradation Angiopoietin-2 differentially regulates angiogenesis through TIE2 and integrin signaling.Acute tumour response to a bispecific Ang-2-VEGF-A antibody: insights from multiparametric MRI and gene expression profiling.Angiopoietin-2 interferes with anti-VEGFR2-induced vessel normalization and survival benefit in mice bearing gliomas.Effect of the vascular endothelial growth factor expression level on angiopoietin-2-mediated nasopharyngeal carcinoma growth.Anti-angiogenic therapy for cancer: current progress, unresolved questions and future directions.Utilizing combinatorial engineering to develop Tie2 targeting antagonistic angiopoetin-2 ligands as candidates for anti-angiogenesis therapy The role of angiopoietins as potential therapeutic targets in renal cell carcinoma.A human neutralizing antibody specific to Ang-2 inhibits ocular angiogenesis.Proteomic screening identifies a YAP-driven signaling network linked to tumor cell proliferation in human schwannomas The antiangiogenic 16K prolactin impairs functional tumor neovascularization by inhibiting vessel maturation.Gentian violet: a 19th century drug re-emerges in the 21st century Regulation of Nur77 expression by β-catenin and its mitogenic effect in colon cancer cells.Chemical generation of bispecific antibodies.Endothelial von Willebrand factor regulates angiogenesis.Angiogenesis and antiangiogenic agents in cervical cancer.Simultaneous silencing of VEGF and KSP by siRNA cocktail inhibits proliferation and induces apoptosis of hepatocellular carcinoma Hep3B cells.A phase 1b, open-label study of trebananib plus bevacizumab or motesanib in patients with solid tumours.Computational selection of RNA aptamer against angiopoietin-2 and experimental evaluation Angiopoietin-2, an angiogenic regulator, promotes initial growth and survival of breast cancer metastases to the lung through the integrin-linked kinase (ILK)-AKT-B cell lymphoma 2 (Bcl-2) pathway Angiogenesis and melanoma - from basic science to clinical trials.Pancreatic endoplasmic reticulum kinase activation promotes medulloblastoma cell migration and invasion through induction of vascular endothelial growth factor A Serum vascular endothelial growth factor and angiopoietin-2 are associated with the severity of systemic inflammation rather than the presence of hemoptysis in patients with inflammatory lung disease.Integrated molecular profiles of invasive breast tumors and ductal carcinoma in situ (DCIS) reveal differential vascular and interleukin signaling Efficacy of Tie2 receptor antagonism in angiosarcoma Effects of angiopoietin-2-blocking antibody on endothelial cell-cell junctions and lung metastasis Lessons from anti-vascular endothelial growth factor and anti-vascular endothelial growth factor receptor trials in patients with glioblastoma.Association of Angiopoietin-2 and Ki-67 Expression with Vascular Density and Sunitinib Response in Metastatic Renal Cell Carcinoma.A novel angiopoietin-derived peptide displays anti-angiogenic activity and inhibits tumour-induced and retinal neovascularization.Gastric tumour-derived ANGPT2 regulation by DARPP-32 promotes angiogenesis The complex role of angiopoietin-2 in the angiopoietin-tie signaling pathway.Alliance A091103 a phase II study of the angiopoietin 1 and 2 peptibody trebananib for the treatment of angiosarcoma.Endothelial cell-derived angiopoietin-2 is a therapeutic target in treatment-naive and bevacizumab-resistant glioblastoma.Angiogenic factors in preeclampsia and related disorders

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Complementary actions of inhibitors of angiopoietin-2 and VEGF on tumor angiogenesis and growth.

http://www.wikidata.org/entity/Q33732486

description

2010 nî lūn-bûn

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2010 թուականի Մարտին հրատարակուած գիտական յօդուած

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2010 թվականի մարտին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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Complementary actions of inhib ...... tumor angiogenesis and growth.

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Complementary actions of inhib ...... tumor angiogenesis and growth.

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Complementary actions of inhib ...... tumor angiogenesis and growth.

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Complementary actions of inhib ...... tumor angiogenesis and growth.

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Complementary actions of inhib ...... tumor angiogenesis and growth.

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0008-5472.CAN-09-1977

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Cancer Research

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Complementary actions of inhib ...... tumor angiogenesis and growth.

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Angela Coxon

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Beverly L Falcón

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Donald M McDonald

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Dongyin Yu

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Hiroya Hashizume

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James V Bready

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Jonathan D Oliner

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Peter Baluk

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Takashi Kuroda

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P2860

Hypoxia and defective apoptosis drive genomic instability and tumorigenesis

Anti-PlGF inhibits growth of VEGF(R)-inhibitor-resistant tumors without affecting healthy vessels

Angiopoietins assemble distinct Tie2 signalling complexes in endothelial cell-cell and cell-matrix contacts

Differential function of Tie2 at cell-cell contacts and cell-substratum contacts regulated by angiopoietin-1

Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis

Contrasting actions of selective inhibitors of angiopoietin-1 and angiopoietin-2 on the normalization of tumor blood vessels

Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors

Suppression of angiogenesis and tumor growth by selective inhibition of angiopoietin-2

Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy

Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis

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2213-2223

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10.1158/0008-5472.CAN-09-1977

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6

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70

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2010-03-02T00:00:00Z

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20197469

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2840050

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