Combined treatment of pancreatic cancer with mithramycin A and tolfenamic acid promotes Sp1 degradation and synergistic antitumor activity
about
Modulation of the activity of Sp transcription factors by mithramycin analogues as a new strategy for treatment of metastatic prostate cancerAnticancer drug mithramycin interacts with core histones: An additional mode of action of the DNA groove binder.Combining betulinic acid and mithramycin a effectively suppresses pancreatic cancer by inhibiting proliferation, invasion, and angiogenesisCrosstalk of Sp1 and Stat3 signaling in pancreatic cancer pathogenesisA novel mithramycin analogue with high antitumor activity and less toxicity generated by combinatorial biosynthesis.Transcriptional Regulation of Frizzled-1 in Human Osteoblasts by Sp1.Relevance of amyloid precursor-like protein 2 C-terminal fragments in pancreatic cancer cells.Activation of alpha(1) -adrenergic receptors stimulate the growth of small mouse cholangiocytes via calcium-dependent activation of nuclear factor of activated T cells 2 and specificity protein 1.Effect of methanol extracts of Cnidium officinale Makino and Capsella bursa-pastoris on the apoptosis of HSC-2 human oral cancer cellsMithramycin A induces apoptosis by regulating the mTOR/Mcl-1/tBid pathway in androgen-independent prostate cancer cells.Specificity protein (Sp) transcription factors Sp1, Sp3 and Sp4 are non-oncogene addiction genes in cancer cells.FOXM1 and its oncogenic signaling in pancreatic cancer pathogenesisNatural glycoconjugates with antitumor activity.Transcription factor Sp1, also known as specificity protein 1 as a therapeutic target.Transcriptional hallmarks of cancer cell lines reveal an emerging role of branched chain amino acid catabolism.Anticancer activity of tolfenamic acid in medulloblastoma: a preclinical study.Sp1king out cancer (....and fibrosis?).Mithramycin-loaded mPEG-PLGA nanoparticles exert potent antitumor efficacy against pancreatic carcinoma.Mithramycin reduces expression of fibro-proliferative mRNAs in human gingival fibroblasts.Sp1 and c-Myc regulate transcription of BMI1 in nasopharyngeal carcinoma.Identification of genes and candidate agents associated with pancreatic cancer.Mithramycin A Alleviates Cognitive Deficits and Reduces Neuropathology in a Transgenic Mouse Model of Alzheimer's Disease.
P2860
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P2860
Combined treatment of pancreatic cancer with mithramycin A and tolfenamic acid promotes Sp1 degradation and synergistic antitumor activity
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Combined treatment of pancreat ...... synergistic antitumor activity
@ast
Combined treatment of pancreat ...... synergistic antitumor activity
@en
type
label
Combined treatment of pancreat ...... synergistic antitumor activity
@ast
Combined treatment of pancreat ...... synergistic antitumor activity
@en
prefLabel
Combined treatment of pancreat ...... synergistic antitumor activity
@ast
Combined treatment of pancreat ...... synergistic antitumor activity
@en
P2093
P2860
P1433
P1476
Combined treatment of pancreat ...... synergistic antitumor activity
@en
P2093
Daoyan Wei
David Z Chang
James C Yao
Keping Xie
Liwei Wang
Suyun Huang
Xiangdong Le
P2860
P304
P356
10.1158/0008-5472.CAN-09-3282
P407
P577
2010-01-19T00:00:00Z