Phenotypic and functional characterisation of the luminal cell hierarchy of the mammary gland. - Wikidata - wikimedia - TriplyDB

Phenotypic and functional characterisation of the luminal cell hierarchy of the mammary gland.

Phenotypic and functional characterisation of the luminal cell hierarchy of the mammary gland.

http://www.wikidata.org/entity/Q33739278

about

Form and function: how estrogen and progesterone regulate the mammary epithelial hierarchy The mammary stem cell hierarchy: a looking glass into heterogeneous breast cancer landscapes ERrrr…where are the progenitors? Hormone receptors and mammary cell heterogeneity BRCA1 and estrogen/estrogen receptor in breast cancer: where they interact?SLUG: Critical regulator of epithelial cell identity in breast development and cancer Mammary stem cells and the differentiation hierarchy: current status and perspectives Luminal progenitors restrict their lineage potential during mammary gland development Sox10 Regulates Stem/Progenitor and Mesenchymal Cell States in Mammary Epithelial Cells.The gene desert mammary carcinoma susceptibility locus Mcs1a regulates Nr2f1 modifying mammary epithelial cell differentiation and proliferation Transcriptional repressor Tbx3 is required for the hormone-sensing cell lineage in mammary epithelium The Hippo kinases LATS1 and 2 control human breast cell fate via crosstalk with ERα The WNT-controlled transcriptional regulator LBH is required for mammary stem cell expansion and maintenance of the basal lineage The Hippo transducer TAZ interacts with the SWI/SNF complex to regulate breast epithelial lineage commitment.Lineage-Biased Stem Cells Maintain Estrogen-Receptor-Positive and -Negative Mouse Mammary Luminal Lineages.Tip30 controls differentiation of murine mammary luminal progenitor to estrogen receptor-positive luminal cell through regulating FoxA1 expression Aberrant Proliferation of Differentiating Alveolar Cells Induces Hyperplasia in Resting Mammary Glands of SV40-TAg Transgenic Mice Aldehyde dehydrogenase and estrogen receptor define a hierarchy of cellular differentiation in the normal human mammary epithelium.Age-related dysfunction in mechanotransduction impairs differentiation of human mammary epithelial progenitors Stem cells and the developing mammary gland.Runx2 is a novel regulator of mammary epithelial cell fate in development and breast cancer Mammary stem cells have myoepithelial cell properties R-spondin1 is a novel hormone mediator for mammary stem cell self-renewal The mammary cellular hierarchy and breast cancer.Combined Single-Cell Functional and Gene Expression Analysis Resolves Heterogeneity within Stem Cell Populations Genotoxic exposure during juvenile growth of mammary gland depletes stem cell activity and inhibits Wnt signaling.The microRNA 424/503 cluster reduces CDC25A expression during cell cycle arrest imposed by transforming growth factor β in mammary epithelial cells Profiling of normal and malignant breast tissue show CD44high/CD24low phenotype as a predominant stem/progenitor marker when used in combination with Ep-CAM/CD49f markers.The dynamics of murine mammary stem/progenitor cells.Developmental changes in the in vitro activated regenerative activity of primitive mammary epithelial cells.Anatomical localization of progenitor cells in human breast tissue reveals enrichment of uncommitted cells within immature lobules The influence of tamoxifen on normal mouse mammary gland homeostasis Luminal progenitor and fetal mammary stem cell expression features predict breast tumor response to neoadjuvant chemotherapy.Transcriptome analysis of the hormone-sensing cells in mammary epithelial reveals dynamic changes in early pregnancy.TOX3 is expressed in mammary ER(+) epithelial cells and regulates ER target genes in luminal breast cancer.A strategy for tissue self-organization that is robust to cellular heterogeneity and plasticity RUNX1, a transcription factor mutated in breast cancer, controls the fate of ER-positive mammary luminal cells.A pooled shRNA screen for regulators of primary mammary stem and progenitor cells identifies roles for Asap1 and Prox1.Models of breast morphogenesis based on localization of stem cells in the developing mammary lobule Bipotent mammary stem cells: now in amazing 3D.MCF-7 Human Breast Cancer Cells Form Differentiated Microtissues in Scaffold-Free Hydrogels.

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P2860

Phenotypic and functional characterisation of the luminal cell hierarchy of the mammary gland.

http://www.wikidata.org/entity/Q33739278

description

2012 nî lūn-bûn

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2012 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2012 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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Phenotypic and functional char ...... ierarchy of the mammary gland.

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Breast Cancer Research

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Andrew Teschendorff

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Christine J Watson

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Gemma Sharp

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I Alasdair Russell

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John Stingl

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Michael Prater

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Stefanie Avril

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P2860

FOXA1 is an essential determinant of ERalpha expression and mammary ductal morphogenesis

ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome

Prospective identification of tumorigenic breast cancer cells

Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications

Untangling the ErbB signalling network

Molecular portraits of human breast tumours

Cellular expression of estrogen and progesterone receptors in mammary glands: regulation by hormones, development and aging

Amphiregulin is an essential mediator of estrogen receptor alpha function in mammary gland development

Defective mammary gland morphogenesis in mice lacking the progesterone receptor B isoform

Essential function of Wnt-4 in mammary gland development downstream of progesterone signaling

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10.1186/BCR3334

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14

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23088371

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4053112

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