Mutation-selection models of coding sequence evolution with site-heterogeneous amino acid fitness profiles.
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Rooting the tree of life: the phylogenetic jury is still outRelaxing the Molecular Clock to Different Degrees for Different Substitution TypesProbabilistic models of eukaryotic evolution: time for integrationContingency and entrenchment in protein evolution under purifying selectionLess is more: an adaptive branch-site random effects model for efficient detection of episodic diversifying selectionA penalized-likelihood method to estimate the distribution of selection coefficients from phylogenetic dataHistory can matter: non-Markovian behavior of ancestral lineagesPredicting the emergence of H3N2 influenza viruses reveals contrasted modes of evolution of HA and NA antigens.Darwin and Fisher meet at biotech: on the potential of computational molecular evolution in industry.The nonadaptive nature of the H1N1 2009 Swine Flu pandemic contrasts with the adaptive facilitation of transmission to a new host.Integrating sequence variation and protein structure to identify sites under selectionImpact of missing data on phylogenies inferred from empirical phylogenomic data sets.Estimating Gene Expression and Codon-Specific Translational Efficiencies, Mutation Biases, and Selection Coefficients from Genomic Data AloneThe tangled bank of amino acids.Modelling the ancestral sequence distribution and model frequencies in context-dependent models for primate non-coding sequences.Site-specific time heterogeneity of the substitution process and its impact on phylogenetic inference.Detecting consistent patterns of directional adaptation using differential selection codon models.An experimentally determined evolutionary model dramatically improves phylogenetic fit.A generalized mechanistic codon modelPhylogenetic stochastic mapping without matrix exponentiation.Estimating the distribution of selection coefficients from phylogenetic data using sitewise mutation-selection models.An experimentally informed evolutionary model improves phylogenetic fit to divergent lactamase homologsSerine codon-usage bias in deep phylogenomics: pancrustacean relationships as a case study.Modeling compositional dynamics based on GC and purine contents of protein-coding sequences.SENCA: A Multilayered Codon Model to Study the Origins and Dynamics of Codon Usage.Mutational studies on resurrected ancestral proteins reveal conservation of site-specific amino acid preferences throughout evolutionary history.Faster than neutral evolution of constrained sequences: the complex interplay of mutational biases and weak selection.The relationship between dN/dS and scaled selection coefficients.A random effects branch-site model for detecting episodic diversifying selection.Statistics and truth in phylogenomics.Pyvolve: A Flexible Python Module for Simulating Sequences along Phylogenies.Assessing the performance of DNA barcoding using posterior predictive simulations.Amino acid coevolution induces an evolutionary Stokes shift.Site-Specific Amino Acid Preferences Are Mostly Conserved in Two Closely Related Protein Homologs.An Integrated Model of Phenotypic Trait Changes and Site-Specific Sequence Evolution.Changing preferences: deformation of single position amino acid fitness landscapes and evolution of proteinsPhylogenetics, likelihood, evolution and complexity.Identification of positive selection in genes is greatly improved by using experimentally informed site-specific models.Molecular phylogenetics: principles and practice.Site-heterogeneous mutation-selection models within the PhyloBayes-MPI package.
P2860
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P2860
Mutation-selection models of coding sequence evolution with site-heterogeneous amino acid fitness profiles.
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Mutation-selection models of c ...... s amino acid fitness profiles.
@ast
Mutation-selection models of c ...... s amino acid fitness profiles.
@en
type
label
Mutation-selection models of c ...... s amino acid fitness profiles.
@ast
Mutation-selection models of c ...... s amino acid fitness profiles.
@en
prefLabel
Mutation-selection models of c ...... s amino acid fitness profiles.
@ast
Mutation-selection models of c ...... s amino acid fitness profiles.
@en
P2093
P2860
P356
P1476
Mutation-selection models of c ...... s amino acid fitness profiles.
@en
P2093
Hervé Philippe
Nicolas Lartillot
Nicolas Rodrigue
P2860
P304
P356
10.1073/PNAS.0910915107
P407
P577
2010-02-22T00:00:00Z