Initiation, elongation, and termination strategies in polyketide and polypeptide antibiotic biosynthesis.
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Mycobacterium tuberculosis Rv3802c encodes a phospholipase/thioesterase and is inhibited by the antimycobacterial agent tetrahydrolipstatinThe insect pathogen Serratia marcescens Db10 uses a hybrid non-ribosomal peptide synthetase-polyketide synthase to produce the antibiotic althiomycin4'-Phosphopantetheinyl transferase PptT, a new drug target required for Mycobacterium tuberculosis growth and persistence in vivoIdentification of the missing trans-acting enoyl reductase required for phthiocerol dimycocerosate and phenolglycolipid biosynthesis in Mycobacterium tuberculosisMicroarray analysis of the Mycobacterium tuberculosis transcriptional response to the acidic conditions found in phagosomesBiosurfactant production and surface translocation are regulated by PlcR in Bacillus cereus ATCC 14579 under low-nutrient conditions.Structure and biosynthesis of the BT peptide antibiotic from Brevibacillus texasporus.Automated genome mining for natural products.Phylogenomics reveals subfamilies of fungal nonribosomal peptide synthetases and their evolutionary relationships.Assembly of aryl-capped siderophores by modular peptide synthetases and polyketide synthases.Analyses of MbtB, MbtE, and MbtF suggest revisions to the mycobactin biosynthesis pathway in Mycobacterium tuberculosisRegeneration of misprimed nonribosomal peptide synthetases by type II thioesterases.The phosphopantetheinyl transferase superfamily: phylogenetic analysis and functional implications in cyanobacteria.Genetics and assembly line enzymology of siderophore biosynthesis in bacteria.Probing intra- versus interchain kinetic preferences of L-Thr acylation on dimeric VibF with mass spectrometry.The nonredundant roles of two 4'-phosphopantetheinyl transferases in vital processes of MycobacteriaFunctional characterization of the acyl-[acyl carrier protein] ligase in the Cryptosporidium parvum giant polyketide synthase.Expression pattern of polyketide synthase-2 during sea urchin development.Phosphopantetheinyl transferase CfwA/NpgA is required for Aspergillus nidulans secondary metabolism and asexual development.Ribozyme catalysis: not different, just worse.Tandem heterocyclization domains in a nonribosomal peptide synthetase essential for siderophore biosynthesis in Vibrio anguillarumQuorum-sensing control of antibiotic synthesis in Burkholderia thailandensisProteus mirabilis genes that contribute to pathogenesis of urinary tract infection: identification of 25 signature-tagged mutants attenuated at least 100-fold.A nonribosomal peptide synthetase with a novel domain organization is essential for siderophore biosynthesis in Vibrio anguillarum.Progress challenges and opportunities for the re-engineering of trans-AT polyketide synthases.Initiation of polyene macrolide biosynthesis: interplay between polyketide synthase domains and modules as revealed via domain swapping, mutagenesis, and heterologous complementation.A Phosphopantetheinyl transferase homolog is essential for Photorhabdus luminescens to support growth and reproduction of the entomopathogenic nematode Heterorhabditis bacteriophora.Photobactin: a catechol siderophore produced by Photorhabdus luminescens, an entomopathogen mutually associated with Heterorhabditis bacteriophora NC1 nematodes.Subcellular localization of dinoflagellate polyketide synthases and fatty acid synthase activity.An orthogonal purification strategy for isolating crosslinked domains of modular synthases.Genetic determinants of reutericyclin biosynthesis in Lactobacillus reuteri.A strategy for the identification of patterns in the biosynthesis of nonribosomal peptides by Betaproteobacteria species.Identification and analysis of the gene cluster involved in biosynthesis of paenibactin, a catecholate siderophore produced by Paenibacillus elgii B69.Gene cluster involved in the biosynthesis of griseobactin, a catechol-peptide siderophore of Streptomyces sp. ATCC 700974.A beta-lysine adenylating enzyme and a beta-lysine binding protein involved in poly beta-lysine chain assembly in nourseothricin synthesis in Streptomyces noursei.Construction of hybrid peptide synthetases for the production of alpha-l-aspartyl-l-phenylalanine, a precursor for the high-intensity sweetener aspartame.The role of firefly luciferase C-terminal domain in efficient coupling of adenylation and oxidative steps.Deciphering the biosynthetic codes for the potent anti-SARS-CoV cyclodepsipeptide valinomycin in Streptomyces tsusimaensis ATCC 15141.A nonribosomal peptide synthetase involved in the biosynthesis of ampullosporins in Sepedonium ampullosporum.A putative polyketide synthase/peptide synthetase from Magnaporthe grisea signals pathogen attack to resistant rice.
P2860
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P2860
Initiation, elongation, and termination strategies in polyketide and polypeptide antibiotic biosynthesis.
description
1999 nî lūn-bûn
@nan
1999 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Initiation, elongation, and te ...... ptide antibiotic biosynthesis.
@ast
Initiation, elongation, and te ...... ptide antibiotic biosynthesis.
@en
type
label
Initiation, elongation, and te ...... ptide antibiotic biosynthesis.
@ast
Initiation, elongation, and te ...... ptide antibiotic biosynthesis.
@en
prefLabel
Initiation, elongation, and te ...... ptide antibiotic biosynthesis.
@ast
Initiation, elongation, and te ...... ptide antibiotic biosynthesis.
@en
P1476
Initiation, elongation, and te ...... ptide antibiotic biosynthesis.
@en
P2093
P304
P356
10.1016/S1367-5931(99)00015-0
P577
1999-10-01T00:00:00Z