Francisella tularensis Schu S4 O-antigen and capsule biosynthesis gene mutants induce early cell death in human macrophages.
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From the Outside-In: The Francisella tularensis Envelope and VirulenceMolecular mechanisms of inflammasome activation during microbial infectionsSubversion of host recognition and defense systems by Francisella sppEvidence Suggesting That Francisella tularensis O-Antigen Capsule Contains a Lipid A-Like Molecule That Is Structurally Distinct from the More Abundant Free Lipid AHost-adaptation of Francisella tularensis alters the bacterium's surface-carbohydrates to hinder effectors of innate and adaptive immunity.The Francisella O-antigen mediates survival in the macrophage cytosol via autophagy avoidance.FTT0831c/FTL_0325 contributes to Francisella tularensis cell division, maintenance of cell shape, and structural integrity.Macrophage replication screen identifies a novel Francisella hydroperoxide resistance protein involved in virulence.Identification of mechanisms for attenuation of the FSC043 mutant of Francisella tularensis SCHU S4.Differential expression of microRNAs in Francisella tularensis-infected human macrophages: miR-155-dependent downregulation of MyD88 inhibits the inflammatory response.Bacterial programming of host responses: coordination between type I interferon and cell death.Isolation and mutagenesis of a capsule-like complex (CLC) from Francisella tularensis, and contribution of the CLC to F. tularensis virulence in miceInnate immune recognition of francisella tularensis: activation of type-I interferons and the inflammasomeIglG and IglI of the Francisella pathogenicity island are important virulence determinants of Francisella tularensis LVSCharacterization of Francisella tularensis Schu S4 mutants identified from a transposon library screened for O-antigen and capsule deficienciesInteractions of Francisella tularensis with Alveolar Type II Epithelial Cells and the Murine Respiratory Epithelium.O-antigen-deficient Francisella tularensis Live Vaccine Strain mutants are ingested via an aberrant form of looping phagocytosis and show altered kinetics of intracellular trafficking in human macrophages.Identifying Francisella tularensis genes required for growth in host cells.Francisella tularensis inhibits the intrinsic and extrinsic pathways to delay constitutive apoptosis and prolong human neutrophil lifespan.Using host-pathogen protein interactions to identify and characterize Francisella tularensis virulence factors.The O-Antigen Capsule of Salmonella enterica Serovar Typhimurium Facilitates Serum Resistance and Surface Expression of FliC.Identification of a novel Francisella tularensis factor required for intramacrophage survival and subversion of innate immune response.Natural IgM mediates complement-dependent uptake of Francisella tularensis by human neutrophils via complement receptors 1 and 3 in nonimmune serum.A spontaneous mutation in kdsD, a biosynthesis gene for 3 Deoxy-D-manno-Octulosonic Acid, occurred in a ciprofloxacin resistant strain of Francisella tularensis and caused a high level of attenuation in murine models of tularemia.Disruption of Francisella tularensis Schu S4 iglI, iglJ, and pdpC genes results in attenuation for growth in human macrophages and in vivo virulence in mice and reveals a unique phenotype for pdpC.Trogocytosis-associated cell to cell spread of intracellular bacterial pathogens.Metabolic Reprogramming of Host Cells by Virulent Francisella tularensis for Optimal Replication and Modulation of Inflammation.Mechanisms of Francisella tularensis intracellular pathogenesis.The Francisella tularensis migR, trmE, and cphA genes contribute to F. tularensis pathogenicity island gene regulation and intracellular growth by modulation of the stress alarmone ppGppBiofilms: an advancement in our understanding of Francisella species.Francisella tularensis Schu S4 lipopolysaccharide core sugar and O-antigen mutants are attenuated in a mouse model of tularemia.TolC-dependent modulation of host cell death by the Francisella tularensis live vaccine strain.Host Defense and the Airway Epithelium: Frontline Responses That Protect against Bacterial Invasion and Pneumonia.Proteins involved in Francisella tularensis survival and replication inside macrophages.The atypical lipopolysaccharide of Francisella.Uncovering the components of the Francisella tularensis virulence stealth strategyElevated AIM2-mediated pyroptosis triggered by hypercytotoxic Francisella mutant strains is attributed to increased intracellular bacteriolysis.Differential Growth of Francisella tularensis, Which Alters Expression of Virulence Factors, Dominant Antigens, and Surface-Carbohydrate Synthases, Governs the Apparent Virulence of Ft SchuS4 to Immunized Animals.A human time dose response model for Q fever.Francisella Inflammasomes: Integrated Responses to a Cytosolic Stealth Bacterium.
P2860
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P2860
Francisella tularensis Schu S4 O-antigen and capsule biosynthesis gene mutants induce early cell death in human macrophages.
description
2010 nî lūn-bûn
@nan
2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Francisella tularensis Schu S4 ...... ll death in human macrophages.
@ast
Francisella tularensis Schu S4 ...... ll death in human macrophages.
@en
type
label
Francisella tularensis Schu S4 ...... ll death in human macrophages.
@ast
Francisella tularensis Schu S4 ...... ll death in human macrophages.
@en
prefLabel
Francisella tularensis Schu S4 ...... ll death in human macrophages.
@ast
Francisella tularensis Schu S4 ...... ll death in human macrophages.
@en
P2093
P2860
P50
P356
P1476
Francisella tularensis Schu S4 ...... ell death in human macrophages
@en
P2093
Denise M Monack
Jason R Hunt
Kaitian Peng
Matthew E Long
Stephen R Lindemann
P2860
P304
P356
10.1128/IAI.00863-10
P407
P577
2010-11-15T00:00:00Z