Inhibitors of protein disulfide isomerase suppress apoptosis induced by misfolded proteins.
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The Unfolded Protein Response and the Role of Protein Disulfide Isomerase in NeurodegenerationProtein disulfide isomerases in neurodegeneration: from disease mechanisms to biomedical applicationsProtein folding and quality control in the ERProtein disulfide isomerase a multifunctional protein with multiple physiological rolesFunctional contribution of the transcription factor ATF4 to the pathogenesis of amyotrophic lateral sclerosisFunctional Role of the Disulfide Isomerase ERp57 in Axonal RegenerationA substrate-driven allosteric switch that enhances PDI catalytic activityHuman Protein-disulfide Isomerase Is a Redox-regulated Chaperone Activated by Oxidation of Domain a′Potential therapeutic approaches for modulating expression and accumulation of defective lamin A in laminopathies and age-related diseasesProteome-wide covalent ligand discovery in native biological systemsPreImplantation factor (PIF) protects cultured embryos against oxidative stress: relevance for recurrent pregnancy loss (RPL) therapy.Thiol isomerases in thrombus formation.Chemical genetics.Protein disulfide isomerase regulates endoplasmic reticulum stress and the apoptotic process during prion infection and PrP mutant-induced cytotoxicity.Protein Disulfide Isomerase Superfamily in Disease and the Regulation of ApoptosisThioredoxin-interacting protein regulates protein disulfide isomerases and endoplasmic reticulum stress.Ferrostatins inhibit oxidative lipid damage and cell death in diverse disease modelsTherapeutic approaches to preventing cell death in Huntington diseaseDifferent interaction modes for protein-disulfide isomerase (PDI) as an efficient regulator and a specific substrate of endoplasmic reticulum oxidoreductin-1α (Ero1α).Small molecule-induced oxidation of protein disulfide isomerase is neuroprotective.Targeting the ERAD pathway via inhibition of signal peptide peptidase for antiparasitic therapeutic designIdentification of a small molecule that induces ATG5-and-cathepsin-l-dependent cell death and modulates polyglutamine toxicity.Protein disulfide isomerase interacts with tau protein and inhibits its fibrillization.Profiling of Proteins Regulated by Venlafaxine during Neural Differentiation of Human CellsIdentification of a lacosamide binding protein using an affinity bait and chemical reporter strategy: 14-3-3 ζ.The nairovirus nairobi sheep disease virus/ganjam virus induces the translocation of protein disulphide isomerase-like oxidoreductases from the endoplasmic reticulum to the cell surface and the extracellular space.A small molecule inhibits protein disulfide isomerase and triggers the chemosensitization of cancer cells.Impaired bone formation in Pdia3 deficient mice.Proapoptotic activities of protein disulfide isomerase (PDI) and PDIA3 protein, a role of the Bcl-2 protein Bak.Novel roles for protein disulphide isomerase in disease states: a double edged sword?Structural Elucidation of a Small Molecule Inhibitor of Protein Disulfide Isomerase.Targeting the UPR transcription factor XBP1 protects against Huntington's disease through the regulation of FoxO1 and autophagy.Broad-spectrum antivirals against viral fusion.Protein disulfide isomerase-endoplasmic reticulum resident protein 57 regulates allergen-induced airways inflammation, fibrosis, and hyperresponsiveness.Discovery of an orally active small-molecule irreversible inhibitor of protein disulfide isomerase for ovarian cancer treatment.Discovery of lacosamide affinity bait agents that exhibit potent voltage-gated sodium channel blocking properties.Risk assessment, disease prevention and personalised treatments in breast cancer: is clinically qualified integrative approach in the horizon?Chronic Heat Stress Induces Immune Response, Oxidative Stress Response, and Apoptosis of Finishing Pig Liver: A Proteomic Approach.Protein disulfide isomerase as a novel target for cyclopentenone prostaglandins: implications for hypoxic ischemic injuryMechanistic evaluation and transcriptional signature of a glutathione S-transferase omega 1 inhibitor
P2860
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P2860
Inhibitors of protein disulfide isomerase suppress apoptosis induced by misfolded proteins.
description
2010 nî lūn-bûn
@nan
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Inhibitors of protein disulfid ...... induced by misfolded proteins.
@ast
Inhibitors of protein disulfid ...... induced by misfolded proteins.
@en
type
label
Inhibitors of protein disulfid ...... induced by misfolded proteins.
@ast
Inhibitors of protein disulfid ...... induced by misfolded proteins.
@en
prefLabel
Inhibitors of protein disulfid ...... induced by misfolded proteins.
@ast
Inhibitors of protein disulfid ...... induced by misfolded proteins.
@en
P2093
P2860
P356
P1476
Inhibitors of protein disulfid ...... induced by misfolded proteins.
@en
P2093
Anna Kaplan
Benjamin G Hoffstrom
Brent R Stockwell
Donald C Lo
Gregory J Turmel
Reka Letso
P2860
P2888
P304
P356
10.1038/NCHEMBIO.467
P50
P577
2010-10-31T00:00:00Z