Mechanisms of typical and atypical antipsychotic drug action in relation to dopamine and NMDA receptor hypofunction hypotheses of schizophrenia.
about
Synthesis, SAR and unanticipated pharmacological profiles of analogues of the mGluR5 ago-potentiator ADX-47273Typical and atypical antipsychotic drug effects on locomotor hyperactivity and deficits in sensorimotor gating in a genetic model of NMDA receptor hypofunction.Neuromapping techniques in drug discovery: pharmacological MRI for the assessment of novel antipsychotics.Do antipsychotic drugs affect brain structure? A systematic and critical review of MRI findings.Pharmacological treatment of schizophrenia: a critical review of the pharmacology and clinical effects of current and future therapeutic agents.Treatments for schizophrenia: a critical review of pharmacology and mechanisms of action of antipsychotic drugs.Definition, psychopharmacological basis and clinical evaluation of novel/atypical neuroleptics: methodological issues and clinical consequences.Effectiveness and tolerability of open label olanzapine in children and adolescents with Tourette syndrome.Do NMDA receptor antagonist models of schizophrenia predict the clinical efficacy of antipsychotic drugs?Tardive dyskinesia is caused by maladaptive synaptic plasticity: a hypothesis.Psychopharmacology of atypical antipsychotic drugs: From the receptor binding profile to neuroprotection and neurogenesis.Thinking and acting beyond the positive: the role of the cognitive and negative symptoms in schizophrenia.The preclinical profile of brexpiprazole: what is its clinical relevance for the treatment of psychiatric disorders?Glutamatergic stimulation induces GluN2B translation by the nitric oxide-Heme-Regulated eIF2α kinase in cortical neurons.Clozapine functions through the prefrontal cortex serotonin 1A receptor to heighten neuronal activity via calmodulin kinase II-NMDA receptor interactions.Chronic administration of atypical antipsychotics improves behavioral and synaptic defects of STOP null mice.The expression of glutamate transporter GLT-1 in the rat cerebral cortex is down-regulated by the antipsychotic drug clozapine.Effects of clozapine on the efflux of serotonin and dopamine in the rat brain: the role of 5-HT1A receptors.The modulatory effects of dopamine D1 and D2 receptor function on object working memory in humans.Glutamate receptor subunits are altered in forebrain and cerebellum in rats chronically exposed to the NMDA receptor antagonist phencyclidine.Synthesis and preliminary screening of novel N-{2-[4-(substituted)piperazin-1-yl]-2-oxoethyl}acetamides as potential atypical antipsychotic agents.Atypical antipsychotics and a Src kinase inhibitor (PP1) prevent cortical injury produced by the psychomimetic, noncompetitive NMDA receptor antagonist MK-801.Acute clozapine suppresses synchronized pyramidal synaptic network activity by increasing inhibition in the ferret prefrontal cortex.Neuroleptics and enrichment environment treatment in memory disorders and other central nervous system function observed in prenatally stressed rats.Effect of olanzapine treatment on platelet glutamine synthetase-like protein and glutamate dehydrogenase immunoreactivity in schizophrenia.
P2860
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P2860
Mechanisms of typical and atypical antipsychotic drug action in relation to dopamine and NMDA receptor hypofunction hypotheses of schizophrenia.
description
1999 nî lūn-bûn
@nan
1999 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Mechanisms of typical and atyp ...... n hypotheses of schizophrenia.
@ast
Mechanisms of typical and atyp ...... n hypotheses of schizophrenia.
@en
type
label
Mechanisms of typical and atyp ...... n hypotheses of schizophrenia.
@ast
Mechanisms of typical and atyp ...... n hypotheses of schizophrenia.
@en
prefLabel
Mechanisms of typical and atyp ...... n hypotheses of schizophrenia.
@ast
Mechanisms of typical and atyp ...... n hypotheses of schizophrenia.
@en
P2093
P356
P1433
P1476
Mechanisms of typical and atyp ...... n hypotheses of schizophrenia.
@en
P2093
P2888
P304
P356
10.1038/SJ.MP.4000581
P407
P577
1999-09-01T00:00:00Z