Mutant p53 exhibits trivial effects on mitochondrial functions which can be reactivated by ellipticine in lymphoma cells.
about
Chemical metabolic inhibitors for the treatment of blood-borne cancersThe anticancer drug ellipticine activated with cytochrome P450 mediates DNA damage determining its pharmacological efficiencies: studies with rats, Hepatic Cytochrome P450 Reductase Null (HRN™) mice and pure enzymes.Negative Regulation of p21Waf1/Cip1 by Human INO80 Chromatin Remodeling Complex Is Implicated in Cell Cycle Phase G2/M Arrest and Abnormal Chromosome Stability.Reactivation of wild-type and mutant p53 by tryptophanolderived oxazoloisoindolinone SLMP53-1, a novel anticancer small-moleculeDysfunction of the TP53 tumor suppressor gene in lymphoid malignancies.Mutational profile and prognostic significance of TP53 in diffuse large B-cell lymphoma patients treated with R-CHOP: report from an International DLBCL Rituximab-CHOP Consortium Program StudyTargeting cancer cell mitochondria as a therapeutic approach.Enhancing mitochondrial respiration suppresses tumor promoter TPA-induced PKM2 expression and cell transformation in skin epidermal JB6 cells.MnSOD in oxidative stress response-potential regulation via mitochondrial protein influx.Oxidative Stress Induced by MnSOD-p53 Interaction: Pro- or Anti-Tumorigenic?Constitutive Activation of DNA Damage Checkpoint Signaling Contributes to Mutant p53 Accumulation via Modulation of p53 Ubiquitination.Molecular mechanisms for tumor resistance to chemotherapy.Mitochondrial p53 phosphorylation induces Bak-mediated and caspase-independent cell death.Mechanisms of resistance to apoptosis in the human acute promyelocytic leukemia cell line NB4.Ellipticine induces apoptosis in T-cell lymphoma via oxidative DNA damage.Nitric oxide (•NO) generation but not ROS plays a major role in silibinin-induced autophagic and apoptotic death in human epidermoid carcinoma A431 cells.Deficiency of the complex I of the mitochondrial respiratory chain but improved adenylate control over succinate-dependent respiration are human gastric cancer-specific phenomena.CK1δ in lymphoma: gene expression and mutation analyses and validation of CK1δ kinase activity for therapeutic application.Stimulation of suicidal erythrocyte death by ellipticine.Isolation, biological activity and synthesis of the natural product ellipticine and related pyridocarbazoles
P2860
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P2860
Mutant p53 exhibits trivial effects on mitochondrial functions which can be reactivated by ellipticine in lymphoma cells.
description
2011 nî lūn-bûn
@nan
2011 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մարտին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Mutant p53 exhibits trivial ef ...... ellipticine in lymphoma cells.
@ast
Mutant p53 exhibits trivial ef ...... ellipticine in lymphoma cells.
@en
type
label
Mutant p53 exhibits trivial ef ...... ellipticine in lymphoma cells.
@ast
Mutant p53 exhibits trivial ef ...... ellipticine in lymphoma cells.
@en
prefLabel
Mutant p53 exhibits trivial ef ...... ellipticine in lymphoma cells.
@ast
Mutant p53 exhibits trivial ef ...... ellipticine in lymphoma cells.
@en
P2093
P2860
P1433
P1476
Mutant p53 exhibits trivial ef ...... ellipticine in lymphoma cells.
@en
P2093
Delira Robbins
Jianfeng Liu
Kerri Morris
Yong-Yu Liu
Yunfeng Zhao
P2860
P2888
P304
P356
10.1007/S10495-010-0559-8
P577
2011-03-01T00:00:00Z