Normal neurogenesis and scrapie pathogenesis in neural grafts lacking the prion protein homologue Doppel

Normal neurogenesis and scrapie pathogenesis in neural grafts lacking the prion protein homologue Doppel

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http://www.wikidata.org/entity/Q33757335
The human "prion-like" protein Doppel is expressed in both Sertoli cells and spermatozoaTemporal dynamics of hippocampal neurogenesis in chronic neurodegeneration.Absence of the prion protein homologue Doppel causes male sterility.Male infertility and DNA damage in Doppel knockout and prion protein/Doppel double-knockout miceDoppel induces degeneration of cerebellar Purkinje cells independently of BaxTransgene-driven expression of the Doppel protein in Purkinje cells causes Purkinje cell degeneration and motor impairmentDisruption of Doppel prevents neurodegeneration in mice with extensive Prnp deletions.Expression of truncated PrP targeted to Purkinje cells of PrP knockout mice causes Purkinje cell death and ataxia.Genetic mapping of activity determinants within cellular prion proteins: N-terminal modules in PrPC offset pro-apoptotic activity of the Doppel helix B/B' region.Stability and conformational properties of doppel, a prion-like protein, and its single-disulphide mutant.The prion-like protein Doppel enhances ovine spermatozoa fertilizing ability.A cluster of familial Creutzfeldt-Jakob disease mutations recapitulate conserved residues in Doppel: a case of molecular mimicry?
P2860

Normal neurogenesis and scrapie pathogenesis in neural grafts lacking the prion protein homologue Doppel

Item
http://www.wikidata.org/entity/Q33757335
description
2001 nî lūn-bûn
@nan
2001 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Normal neurogenesis and scrapi ...... prion protein homologue Doppel
@ast
Normal neurogenesis and scrapi ...... prion protein homologue Doppel
@en
type
label
Normal neurogenesis and scrapi ...... prion protein homologue Doppel
@ast
Normal neurogenesis and scrapi ...... prion protein homologue Doppel
@en
prefLabel
Normal neurogenesis and scrapi ...... prion protein homologue Doppel
@ast
Normal neurogenesis and scrapi ...... prion protein homologue Doppel
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P577
P5875
P698
P921
P932
P356
P1433
P1476
Normal neurogenesis and scrapi ...... prion protein homologue Doppel
@en
P2093
P2860
P304
P31
P356
10.1093/EMBO-REPORTS/KVE088
P433
P478
P577
P5875
P698
P921
P932