Novel critical role of a human Mediator complex for basal RNA polymerase II transcription
about
The basal transcription machinery as a target for cancer therapySubunit architecture and functional modular rearrangements of the transcriptional mediator complexTRIM11 binds to and destabilizes a key component of the activator-mediated cofactor complex (ARC105) through the ubiquitin-proteasome systemRepression of promoter activity by CNOT2, a subunit of the transcription regulatory Ccr4-not complexMediator modulates Gli3-dependent Sonic hedgehog signalingHuman mediator subunit MED26 functions as a docking site for transcription elongation factorsRequirement of TRAP/mediator for both activator-independent and activator-dependent transcription in conjunction with TFIID-associated TAF(II)s.TRAP/SMCC/mediator-dependent transcriptional activation from DNA and chromatin templates by orphan nuclear receptor hepatocyte nuclear factor 4.Activator-independent functions of the yeast mediator sin4 complex in preinitiation complex formation and transcription reinitiationRole of metazoan mediator proteins in interferon-responsive transcriptionA novel docking site on Mediator is critical for activation by VP16 in mammalian cellsTFIID and human mediator coactivator complexes assemble cooperatively on promoter DNAImportance of Mediator complex in the regulation and integration of diverse signaling pathways in plantsMediator-dependent nuclear receptor functionMediator as a general transcription factor.Srb5/Med18-mediated termination of transcription is dependent on gene loopingThe human Mediator complex: a versatile, genome-wide regulator of transcriptionThe Mediator complex and transcription regulationThe TRAP100 component of the TRAP/Mediator complex is essential in broad transcriptional events and developmentDisordered proteinaceous machinesCharacterization of transcription from TATA-less promoters: identification of a new core promoter element XCPE2 and analysis of factor requirements.Two modes of transcriptional activation at native promoters by NF-kappaB p65Mutation analysis of components of the Mediator kinase module in MED12 mutation-negative uterine leiomyomas.Cyclin-dependent kinase 8 positively cooperates with Mediator to promote thyroid hormone receptor-dependent transcriptional activationThe functions of Mediator in Candida albicans support a role in shaping species-specific gene expression.Mediator and p300/CBP-steroid receptor coactivator complexes have distinct roles, but function synergistically, during estrogen receptor alpha-dependent transcription with chromatin templates.A functional portrait of Med7 and the mediator complex in Candida albicansReconstitution of active human core Mediator complex reveals a critical role of the MED14 subunit.A Mediator-responsive form of metazoan RNA polymerase II.Function and regulation of the Mediator complex.The cyclin-dependent kinase 8 module sterically blocks Mediator interactions with RNA polymerase II.TRAP230/ARC240 and TRAP240/ARC250 Mediator subunits are functionally conserved through evolution.Novel role for mediator complex subunit Srb5/Med18 in termination of transcription.Core promoter-selective function of HMGA1 and Mediator in Initiator-dependent transcription.Human mediator enhances activator-facilitated recruitment of RNA polymerase II and promoter recognition by TATA-binding protein (TBP) independently of TBP-associated factors.Identification of a regulator of transcription elongation as an accessory factor for the human Mediator coactivator.Transcriptional regulation and the role of diverse coactivators in animal cells.Proteomic analysis demonstrates activator- and chromatin-specific recruitment to promoters.Activation domain-mediator interactions promote transcription preinitiation complex assembly on promoter DNAAlternative mechanisms by which mediator subunit MED1/TRAP220 regulates peroxisome proliferator-activated receptor gamma-stimulated adipogenesis and target gene expression.
P2860
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P2860
Novel critical role of a human Mediator complex for basal RNA polymerase II transcription
description
2001 nî lūn-bûn
@nan
2001 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Novel critical role of a human Mediator complex for basal RNA polymerase II transcription
@ast
Novel critical role of a human Mediator complex for basal RNA polymerase II transcription
@en
type
label
Novel critical role of a human Mediator complex for basal RNA polymerase II transcription
@ast
Novel critical role of a human Mediator complex for basal RNA polymerase II transcription
@en
prefLabel
Novel critical role of a human Mediator complex for basal RNA polymerase II transcription
@ast
Novel critical role of a human Mediator complex for basal RNA polymerase II transcription
@en
P2093
P2860
P356
P1433
P1476
Novel critical role of a human Mediator complex for basal RNA polymerase II transcription
@en
P2093
Meisterernst M
Timmers HT
P2860
P304
P356
10.1093/EMBO-REPORTS/KVE186
P577
2001-09-01T00:00:00Z