Differential binding of Escherichia coli enterotoxins LT-IIa and LT-IIb and of cholera toxin elicits differences in apoptosis, proliferation, and activation of lymphoid cells.
about
Immune Adjuvant Effect of Molecularly-defined Toll-Like Receptor LigandsCholera toxin, LT-I, LT-IIa and LT-IIb: the critical role of ganglioside binding in immunomodulation by type I and type II heat-labile enterotoxins.Enhanced antigen uptake by dendritic cells induced by the B pentamer of the type II heat-labile enterotoxin LT-IIa requires engagement of TLR2.Binding to gangliosides containing N-acetylneuraminic acid is sufficient to mediate the immunomodulatory properties of the nontoxic mucosal adjuvant LT-IIb(T13I)LT-IIc, a new member of the type II heat-labile enterotoxin family, exhibits potent immunomodulatory properties that are different from those induced by LT-IIa or LT-IIb.Functional diversity of heat-labile toxins (LT) produced by enterotoxigenic Escherichia coli: differential enzymatic and immunological activities of LT1 (hLT) AND LT4 (pLT)Intradermal administration of the Type II heat-labile enterotoxins LT-IIb and LT-IIc of enterotoxigenic Escherichia coli enhances humoral and CD8+ T cell immunity to a co-administered antigenCharacterization of antigen-presenting cells induced by intragastric immunization with recombinant chimeric immunogens constructed from Streptococcus mutans AgI/II and type I or type II heat-labile enterotoxinsDistinctive immunomodulatory and inflammatory properties of the Escherichia coli type II heat-labile enterotoxin LT-IIa and its B pentamer following intradermal administration.Different types of cell death induced by enterotoxins.Cell clustering and delay/arrest in T-cell division implicate a novel mechanism of immune modulation by E. coli heat-labile enterotoxin B-subunits.Mutants of type II heat-labile enterotoxin LT-IIa with altered ganglioside-binding activities and diminished toxicity are potent mucosal adjuvants.In vitro induction of immunoglobulin A (IgA)- and IgM-secreting plasma blasts by cholera toxin depends on T-cell help and is mediated by CD154 up-regulation and inhibition of gamma interferon synthesisBacterial Toxin Fusion Proteins Elicit Mucosal Immunity against a Foot-and-Mouth Disease Virus Antigen When Administered Intranasally to Guinea PigsImmunomodulation with enterotoxins for the generation of secretory immunity or tolerance: applications for oral infections.Cholera toxin and Escherichia coli heat-labile enterotoxin, but not their nontoxic counterparts, improve the antigen-presenting cell function of human B lymphocytesHeat-labile enterotoxins as adjuvants or anti-inflammatory agents.Glycosphingolipid functionsToxins-useful biochemical tools for leukocyte research.Type II heat-labile enterotoxins: structure, function, and immunomodulatory properties.Direct manipulation of T lymphocytes by proteins of gastrointestinal bacterial pathogens.
P2860
Q28972540-FA09C900-41A2-47FF-887B-576309C013EFQ33768109-A6C5979E-EB83-4A3E-9187-9D7F0BA4751FQ33820591-19759CE4-571D-4CB7-8EA9-28B88C3F266AQ33909162-AC8798DB-678D-4F5E-BEC5-61F0D3EB7E13Q34558281-D4702012-4AE5-4E9C-BAFD-D3D84DF77C64Q34568384-9C3CEB63-DBB9-4A17-AC30-4CA143FFE4D8Q34764532-EF86C46C-0C81-496F-A5EF-C0FA37BF2637Q34972133-3F623EF4-8545-4A9F-8297-9574E8508504Q35138744-105197B2-FF64-4929-BB15-328A2FC716BFQ35155921-D2E4B7C0-051A-449A-A82B-2CE7C6606AE6Q35630112-1191A465-06E9-4F02-AE7C-23E2C3EB67C6Q35689341-6905C635-0E76-4D5E-B887-2B6E2FAF36D5Q35689492-2FE32BEC-64A5-4798-9823-50445CD11575Q35692346-9304FA9E-EA14-46D0-86C7-BE73670A224DQ36320323-04EC1DFB-A947-43A2-B19C-73DA47446955Q37191283-A94D4C5C-B5F0-44D9-9F3B-8586E17CAFCFQ37749719-58A6AB8C-4F8A-465A-8A1C-D196EA5C5726Q37873655-811CD4B2-490D-4A9F-AA03-C0DC4552240EQ37954284-C87CD155-0936-47DD-AA12-B2D7771459BDQ38058640-F6A51F86-73B6-4AF6-A79D-30E20CDCDAD4Q50020365-00D9A07A-CF85-4DC6-B70A-9665BDE68A5E
P2860
Differential binding of Escherichia coli enterotoxins LT-IIa and LT-IIb and of cholera toxin elicits differences in apoptosis, proliferation, and activation of lymphoid cells.
description
2005 nî lūn-bûn
@nan
2005 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Differential binding of Escher ...... activation of lymphoid cells.
@ast
Differential binding of Escher ...... activation of lymphoid cells.
@en
type
label
Differential binding of Escher ...... activation of lymphoid cells.
@ast
Differential binding of Escher ...... activation of lymphoid cells.
@en
prefLabel
Differential binding of Escher ...... activation of lymphoid cells.
@ast
Differential binding of Escher ...... activation of lymphoid cells.
@en
P2093
P2860
P1476
Differential binding of Escher ...... d activation of lymphoid cells
@en
P2093
Hesham F Nawar
Sergio Arce
Terry D Connell
P2860
P304
P356
10.1128/IAI.73.5.2718-2727.2005
P407
P577
2005-05-01T00:00:00Z