The ORF3 protein of hepatitis E virus delays degradation of activated growth factor receptors by interacting with CIN85 and blocking formation of the Cbl-CIN85 complex.
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Molecular Biology and Infection of Hepatitis E VirusTherapeutic targets for the treatment of hepatitis E virus infectionThe hepatitis E virus ORF3 protein regulates the expression of liver-specific genes by modulating localization of hepatocyte nuclear factor 4Inhibition of CIN85-mediated invasion by a novel SH3 domain binding motif in the lysyl oxidase propeptide.The PSAP motif within the ORF3 protein of an avian strain of the hepatitis E virus is not critical for viral infectivity in vivo but plays a role in virus release.Review article: hepatitis E-a concise review of virology, epidemiology, clinical presentation and therapy.Molecular virology of hepatitis E virus.Construction of an infectious cDNA clone of avian hepatitis E virus (avian HEV) recovered from a clinically healthy chicken in the United States and characterization of its pathogenicity in specific-pathogen-free chickens.The nucleotides on the stem-loop RNA structure in the junction region of the hepatitis E virus genome are critical for virus replication.Molecular biology and replication of hepatitis E virus.Virus host protein interaction network analysis reveals that the HEV ORF3 protein may interrupt the blood coagulation processThree amino acid mutations (F51L, T59A, and S390L) in the capsid protein of the hepatitis E virus collectively contribute to virus attenuation.Hepatitis E virus open reading frame 3 protein interacts with porcine liver-specific plasminogen and α2-antiplasmin.RNA-seq based transcriptome analysis of hepatitis E virus (HEV) and hepatitis B virus (HBV) replicon transfected Huh-7 cells.Mutational analysis of the hypervariable region of hepatitis e virus reveals its involvement in the efficiency of viral RNA replicationMolecular detection of hepatitis E virus in sheep from southern Xinjiang, China.Hepatitis E virus replication requires an active ubiquitin-proteasome system.Production of monoclonal antibodies against the ORF3 protein of rat hepatitis E virus (HEV) and demonstration of the incorporation of the ORF3 protein into enveloped rat HEV particles.Antigenic determinants of hepatitis E virus and vaccine-induced immunogenicity and efficacy.Efficient cell culture systems for hepatitis E virus strains in feces and circulating blood.Hepatitis E virus: neutralizing sites, diagnosis, and protective immunity.Characteristics and Functions of HEV Proteins.Hepatitis E virus infection activates signal regulator protein α to down-regulate type I interferon.Full-length sequence analysis of hepatitis E virus isolates: showing potential determinants of virus genotype and identity.An ethanol extract of Lysimachia mauritiana exhibits inhibitory activity against hepatitis E virus genotype 3 replication.Hepatitis E virus: advances and challenges.
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P2860
The ORF3 protein of hepatitis E virus delays degradation of activated growth factor receptors by interacting with CIN85 and blocking formation of the Cbl-CIN85 complex.
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
The ORF3 protein of hepatitis ...... tion of the Cbl-CIN85 complex.
@ast
The ORF3 protein of hepatitis ...... tion of the Cbl-CIN85 complex.
@en
type
label
The ORF3 protein of hepatitis ...... tion of the Cbl-CIN85 complex.
@ast
The ORF3 protein of hepatitis ...... tion of the Cbl-CIN85 complex.
@en
prefLabel
The ORF3 protein of hepatitis ...... tion of the Cbl-CIN85 complex.
@ast
The ORF3 protein of hepatitis ...... tion of the Cbl-CIN85 complex.
@en
P2860
P356
P1433
P1476
The ORF3 protein of hepatitis ...... tion of the Cbl-CIN85 complex.
@en
P2093
Krishnan Hajela
Shahid Jameel
P2860
P304
P356
10.1128/JVI.01994-09
P577
2010-02-03T00:00:00Z