CXCR-4 is expressed by primary macrophages and supports CCR5-independent infection by dual-tropic but not T-tropic isolates of human immunodeficiency virus type 1
about
CCR8 on human thymocytes functions as a human immunodeficiency virus type 1 coreceptor.Role for CCR5Delta32 protein in resistance to R5, R5X4, and X4 human immunodeficiency virus type 1 in primary CD4+ cellsSelective CXCR4 antagonism by Tat: implications for in vivo expansion of coreceptor use by HIV-1HIV-1 gp120 and chemokines activate ion channels in primary macrophages through CCR5 and CXCR4 stimulationThe macrophage: a therapeutic target in HIV-1 infectionHIV-1 envelope-receptor interactions required for macrophage infection and implications for current HIV-1 cure strategiesPotent, broad-spectrum inhibition of human immunodeficiency virus type 1 by the CCR5 monoclonal antibody PRO 140Substance P antagonist (CP-96,345) inhibits HIV-1 replication in human mononuclear phagocytesRole of CXCR4 in cell-cell fusion and infection of monocyte-derived macrophages by primary human immunodeficiency virus type 1 (HIV-1) strains: two distinct mechanisms of HIV-1 dual tropism.Preferential use of CXCR4 by R5X4 human immunodeficiency virus type 1 isolates for infection of primary lymphocytesHuman peritoneal macrophages from ascitic fluid can be infected by a broad range of HIV-1 isolates.Determinants of entry cofactor utilization and tropism in a dualtropic human immunodeficiency virus type 1 primary isolate.Expression and use of human immunodeficiency virus type 1 coreceptors by human alveolar macrophagesMutagenesis of CXCR4 identifies important domains for human immunodeficiency virus type 1 X4 isolate envelope-mediated membrane fusion and virus entry and reveals cryptic coreceptor activity for R5 isolatesInterleukin-16 inhibits human immunodeficiency virus type 1 entry and replication in macrophages and in dendritic cellsThe level of CD4 expression limits infection of primary rhesus monkey macrophages by a T-tropic simian immunodeficiency virus and macrophagetropic human immunodeficiency viruses.Molecular basis for cell tropism of CXCR4-dependent human immunodeficiency virus type 1 isolatesMacrophage tropism of human immunodeficiency virus type 1 isolates from brain and lymphoid tissues predicts neurotropism independent of coreceptor specificity.Induction of rapid and extensive beta-chemokine synthesis in macrophages by human immunodeficiency virus type 1 and gp120, independently of their coreceptor phenotype.Ability of the V3 loop of simian immunodeficiency virus to serve as a target for antibody-mediated neutralization: correlation of neutralization sensitivity, growth in macrophages, and decreased dependence on CD4No selection for CCR5 coreceptor usage during parenteral transmission of macrophagetropic syncytium-inducing human immunodeficiency virus type 1.Preferential coreceptor utilization and cytopathicity by dual-tropic HIV-1 in human lymphoid tissue ex vivo.Receptors and entry cofactors for retroviruses include single and multiple transmembrane-spanning proteins as well as newly described glycophosphatidylinositol-anchored and secreted proteins.Amino acid deletions are introduced into the V2 region of gp120 during independent pathogenic simian immunodeficiency virus/HIV chimeric virus (SHIV) infections of rhesus monkeys generating variants that are macrophage tropic.Macrophage-tropic simian/human immunodeficiency virus chimeras use CXCR4, not CCR5, for infections of rhesus macaque peripheral blood mononuclear cells and alveolar macrophagesRhabdovirus-based vectors with human immunodeficiency virus type 1 (HIV-1) envelopes display HIV-1-like tropism and target human dendritic cells.Increased CCR5 affinity and reduced CCR5/CD4 dependence of a neurovirulent primary human immunodeficiency virus type 1 isolate.Interleukin-8 and growth-regulated oncogene alpha mediate angiogenesis in Kaposi's sarcoma.Genetic and functional analysis of R5X4 human immunodeficiency virus type 1 envelope glycoproteins derived from two individuals homozygous for the CCR5delta32 alleleHIV-1 infection inhibits cytokine production in human thymic macrophages.Successful isolation of infectious and high titer human monocyte-derived HIV-1 from two subjects with discontinued therapyIdentification of a subset of human immunodeficiency virus type 1 (HIV-1), HIV-2, and simian immunodeficiency virus strains able to exploit an alternative coreceptor on untransformed human brain and lymphoid cells.R5X4 HIV-1 coreceptor use in primary target cells: implications for coreceptor entry blocking strategies.Intrinsic obstacles to human immunodeficiency virus type 1 coreceptor switching.Human immunodeficiency virus infects human seminal vesicles in vitro and in vivo.HIV reservoirs in vivo and new strategies for possible eradication of HIV from the reservoir sites.Susceptibility of human testis to human immunodeficiency virus-1 infection in situ and in vitroHuman immunodeficiency virus infection of the brain: pitfalls in evaluating infected/affected cell populations.Quantification of CD4, CCR5, and CXCR4 levels on lymphocyte subsets, dendritic cells, and differentially conditioned monocyte-derived macrophagesDifferential effects of HIV infected macrophages on dorsal root ganglia neurons and axons
P2860
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P2860
CXCR-4 is expressed by primary macrophages and supports CCR5-independent infection by dual-tropic but not T-tropic isolates of human immunodeficiency virus type 1
description
1998 nî lūn-bûn
@nan
1998 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
CXCR-4 is expressed by primary ...... immunodeficiency virus type 1
@ast
CXCR-4 is expressed by primary ...... immunodeficiency virus type 1
@en
type
label
CXCR-4 is expressed by primary ...... immunodeficiency virus type 1
@ast
CXCR-4 is expressed by primary ...... immunodeficiency virus type 1
@en
prefLabel
CXCR-4 is expressed by primary ...... immunodeficiency virus type 1
@ast
CXCR-4 is expressed by primary ...... immunodeficiency virus type 1
@en
P2093
P2860
P1433
P1476
CXCR-4 is expressed by primary ...... immunodeficiency virus type 1
@en
P2093
P2860
P304
P577
1998-01-01T00:00:00Z