Humanized SFTPA1 and SFTPA2 transgenic mice reveal functional divergence of SP-A1 and SP-A2: formation of tubular myelin in vivo requires both gene products
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Genetic complexity of the human surfactant-associated proteins SP-A1 and SP-A2The untranslated exon B of human surfactant protein A2 mRNAs is an enhancer for transcription and translationHuman SP-A1 (SFTPA1) variant-specific 3' UTRs and poly(A) tail differentially affect the in vitro translation of a reporter geneGenetic variant associations of human SP-A and SP-D with acute and chronic lung injury14-3-3 isoforms bind directly exon B of the 5'-UTR of human surfactant protein A2 mRNAHousing conditions modulate the severity of Mycoplasma pulmonis infection in mice deficient in class A scavenger receptorSurfactant protein A associated with respiratory distress syndrome in Korean preterm infants: evidence of ethnic difference.Genetic risk factors associated with respiratory distress syndromeAn 11-nt sequence polymorphism at the 3'UTR of human SFTPA1 and SFTPA2 gene variants differentially affect gene expression levels and miRNA regulation in cell cultureIdentification and Quantitation of Coding Variants and Isoforms of Pulmonary Surfactant Protein A.Sex differences in the acute in vivo effects of different human SP-A variants on the mouse alveolar macrophage proteome.Exon B of human surfactant protein A2 mRNA, alone or within its surrounding sequences, interacts with 14-3-3; role of cis-elements and secondary structure.Knockdown of Drosha in human alveolar type II cells alters expression of SP-A in culture: a pilot study.Electroporation-mediated gene delivery of Na+,K+ -ATPase, and ENaC subunits to the lung attenuates acute respiratory distress syndrome in a two-hit porcine model.Role of surfactant proteins A and D in sepsis-induced acute kidney injury.Regulation of translation by upstream translation initiation codons of surfactant protein A1 splice variants.DNA methylation profile and expression of surfactant protein A2 gene in lung cancer.In vivo rescue of alveolar macrophages from SP-A knockout mice with exogenous SP-A nearly restores a wild type intracellular proteome; actin involvement.Protective Role of Surfactant Protein D in Ocular Staphylococcus aureus InfectionInnate Immune Molecule Surfactant Protein D Attenuates Sepsis-induced Acute Pancreatic Injury through Modulating Apoptosis and NF-κB-mediated Inflammation.Differential susceptibility of transgenic mice expressing human surfactant protein B genetic variants to Pseudomonas aeruginosa induced pneumoniaSex differences in the response of the alveolar macrophage proteome to treatment with exogenous surfactant protein-A.DIFFERENTIAL SUSCEPTIBILITY OF HUMAN SP-B GENETIC VARIANTS ON LUNG INJURY CAUSED BY BACTERIAL PNEUMONIA AND THE EFFECT OF A CHEMICALLY MODIFIED CURCUMIN.Single-cell analysis reveals differential regulation of the alveolar macrophage actin cytoskeleton by surfactant proteins A1 and A2: implications of sex and aging.Differences in the alveolar macrophage proteome in transgenic mice expressing human SP-A1 and SP-A2Influence of genetic variability at the surfactant proteins A and D in community-acquired pneumonia: a prospective, observational, genetic study.Germline SFTPA1 mutation in familial idiopathic interstitial pneumonia and lung cancer.Human Pulmonary Surfactant Protein SP-A1 Provides Maximal Efficiency of Lung Interfacial FilmsSP-A2 contributes to miRNA-mediated sex differences in response to oxidative stress: pro-inflammatory, anti-apoptotic, and anti-oxidant pathways are involved.Differential effects of innate immune variants of surfactant protein-A1 (SFTPA1) and SP-A2 (SFTPA2) in airway function after Klebsiella pneumoniae infection and sex differences.Surfactant protein D attenuates acute lung and kidney injuries in pneumonia-induced sepsis through modulating apoptosis, inflammation and NF-κB signalingSurvival of Surfactant Protein-A1 and SP-A2 Transgenic Mice After Infection, Exhibits Sex-, Gene-, and Variant Specific Differences; Treatment With Surfactant Protein Improves Survival
P2860
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P2860
Humanized SFTPA1 and SFTPA2 transgenic mice reveal functional divergence of SP-A1 and SP-A2: formation of tubular myelin in vivo requires both gene products
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Humanized SFTPA1 and SFTPA2 tr ...... vo requires both gene products
@ast
Humanized SFTPA1 and SFTPA2 tr ...... vo requires both gene products
@en
type
label
Humanized SFTPA1 and SFTPA2 tr ...... vo requires both gene products
@ast
Humanized SFTPA1 and SFTPA2 tr ...... vo requires both gene products
@en
prefLabel
Humanized SFTPA1 and SFTPA2 tr ...... vo requires both gene products
@ast
Humanized SFTPA1 and SFTPA2 tr ...... vo requires both gene products
@en
P2093
P2860
P356
P1476
Humanized SFTPA1 and SFTPA2 tr ...... vo requires both gene products
@en
P2093
Guirong Wang
Joanna Floros
Neal J Thomas
Susan Diangelo
Xiaoxuan Guo
P2860
P304
11998-12010
P356
10.1074/JBC.M109.046243
P407
P577
2010-01-04T00:00:00Z