Bioactive lysophospholipids and their G protein-coupled receptors.
about
Tumor cell invasion of collagen matrices requires coordinate lipid agonist-induced G-protein and membrane-type matrix metalloproteinase-1-dependent signalingPhysical and functional interactions of the lysophosphatidic acid receptors with PDZ domain-containing Rho guanine nucleotide exchange factors (RhoGEFs)Biochemical and molecular characterization of two phosphatidic acid-selective phospholipase A1s, mPA-PLA1alpha and mPA-PLA1betaConvergence of multiple signaling cascades at glycogen synthase kinase 3: Edg receptor-mediated phosphorylation and inactivation by lysophosphatidic acid through a protein kinase C-dependent intracellular pathway.Edg-1, the G protein-coupled receptor for sphingosine-1-phosphate, is essential for vascular maturationAutotaxin has lysophospholipase D activity leading to tumor cell growth and motility by lysophosphatidic acid productionMAGI-3 regulates LPA-induced activation of Erk and RhoAOver-expression of lysophosphatidic acid receptor-2 in human invasive ductal carcinomaG-Protein-Coupled Lysophosphatidic Acid Receptors and Their Regulation of AKT SignalingLipid phosphate phosphatase (LPP3) and vascular developmentBiochemical and Structural Characterization of Lysophosphatidic Acid Binding by a Humanized Monoclonal AntibodyNrg-1 belongs to the endothelial differentiation gene family of G protein-coupled sphingosine-1-phosphate receptorsA novel phosphatidic acid-selective phospholipase A1 that produces lysophosphatidic acidLysophosphatidic acid (LPA) receptors are activated differentially by biological fluids: possible role of LPA-binding proteins in activation of LPA receptorsSphingosylphosphorylcholine and lysophosphatidylcholine are ligands for the G protein-coupled receptor GPR4Regulation of G protein-linked guanine nucleotide exchange factors for Rho, PDZ-RhoGEF, and LARG by tyrosine phosphorylation: evidence of a role for focal adhesion kinasePulmonary phosphatidic acid phosphatase and lipid phosphate phosphohydrolaseVisualization of the pH-dependent dynamic distribution of G2A in living cellsActivation of p21-activated kinase 1 is required for lysophosphatidic acid-induced focal adhesion kinase phosphorylation and cell motility in human melanoma A2058 cellsLPA stimulates intestinal DRA gene transcription via LPA2 receptor, PI3K/AKT, and c-Fos-dependent pathwayStructural basis for metal ion coordination and the catalytic mechanism of sphingomyelinases DExtracellular mechanism through the Edg family of receptors might be responsible for sphingosine-1-phosphate-induced regulation of DNA synthesis and migration of rat aortic smooth-muscle cellsVisualization of elementary mechanosensitive Ca2+-influx events, Ca2+ spots, in bovine lens epithelial cellsCDA: combinatorial drug discovery using transcriptional response modulesExpression and function of lysophosphatidic acid receptors in cultured rodent microglial cellsSpecific receptor subtype mediation of LPA-induced dual effects in cardiac fibroblastsMolecular cloning and expression regulation of PRG-3, a new member of the plasticity-related gene familyInhibitory regulation of Rac activation, membrane ruffling, and cell migration by the G protein-coupled sphingosine-1-phosphate receptor EDG5 but not EDG1 or EDG3Selective loss of sphingosine 1-phosphate signaling with no obvious phenotypic abnormality in mice lacking its G protein-coupled receptor, LP(B3)/EDG-3Molecular genetics of ependymomaG(i)-mediated Cas tyrosine phosphorylation in vascular endothelial cells stimulated with sphingosine 1-phosphate: possible involvement in cell motility enhancement in cooperation with Rho-mediated pathways.Apoptotic effect of sphingosine 1-phosphate and increased sphingosine 1-phosphate hydrolysis on mesangial cells cultured at low cell density.Quantitative analysis of lysophosphatidic acid by time-of-flight mass spectrometry using a phosphate-capture molecule.E2F8 is a nonreceptor activator of heterotrimeric G proteins.Cadherin-bound beta-catenin feeds into the Wnt pathway upon adherens junctions dissociation: evidence for an intersection between beta-catenin pools.Hepatic overexpression of glycerol-sn-3-phosphate acyltransferase 1 in rats causes insulin resistance.G protein-coupled lysophosphatidic acid receptors stimulate proliferation of colon cancer cells through the {beta}-catenin pathway.Lysophosphatidic acid induces MDA-MB-231 breast cancer cells migration through activation of PI3K/PAK1/ERK signaling.Dual regulation of actin rearrangement through lysophosphatidic acid receptor in neuroblast cell lines: actin depolymerization by Ca(2+)-alpha-actinin and polymerization by rhoIntracellular signaling pathways that regulate dendritic spine morphogenesis.
P2860
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P2860
Bioactive lysophospholipids and their G protein-coupled receptors.
description
1999 nî lūn-bûn
@nan
1999 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Bioactive lysophospholipids and their G protein-coupled receptors.
@ast
Bioactive lysophospholipids and their G protein-coupled receptors.
@en
type
label
Bioactive lysophospholipids and their G protein-coupled receptors.
@ast
Bioactive lysophospholipids and their G protein-coupled receptors.
@en
prefLabel
Bioactive lysophospholipids and their G protein-coupled receptors.
@ast
Bioactive lysophospholipids and their G protein-coupled receptors.
@en
P356
P1476
Bioactive lysophospholipids and their G protein-coupled receptors.
@en
P2093
Moolenaar WH
P304
P356
10.1006/EXCR.1999.4702
P407
P577
1999-11-01T00:00:00Z