Identification and characterization of the phosphorylation sites of the guanylyl cyclase-linked natriuretic peptide receptors A and B.
about
Defective cellular trafficking of missense NPR-B mutants is the major mechanism underlying acromesomelic dysplasia-type MaroteauxGREBP, a cGMP-response element-binding protein repressing the transcription of natriuretic peptide receptor 1 (NPR1/GCA).High density and ligand affinity confer ultrasensitive signal detection by a guanylyl cyclase chemoreceptor.A functional screen provides evidence for a conserved, regulatory, juxtamembrane phosphorylation site in guanylyl cyclase a and B.Calcineurin regulates homologous desensitization of natriuretic peptide receptor-A and inhibits ANP-induced testosterone production in MA-10 cells.Allosteric modification, the primary ATP activation mechanism of atrial natriuretic factor receptor guanylate cyclaseANP-induced signaling cascade and its implications in renal pathophysiologyHomologous and heterologous desensitization of guanylyl cyclase-B signaling in GH3 somatolactotropesAtrial natriuretic factor receptor guanylate cyclase, ANF-RGC, transduces two independent signals, ANF and Ca(2+).Homologous desensitization of guanylyl cyclase A, the receptor for atrial natriuretic peptide, is associated with a complex phosphorylation pattern.Csk mediates G-protein-coupled lysophosphatidic acid receptor-induced inhibition of membrane-bound guanylyl cyclase activity.Atrial natriuretic peptide-dependent photolabeling of a regulatory ATP-binding site on the natriuretic peptide receptor-A.Effects of cyclic nucleotides on the function of prestin.Agonistic induction of a covalent dimer in a mutant of natriuretic peptide receptor-A documents a juxtamembrane interaction that accompanies receptor activation.Activation of protein kinase C stimulates the dephosphorylation of natriuretic peptide receptor-B at a single serine residue: a possible mechanism of heterologous desensitization.Mass spectrometric identification of phosphorylation sites in guanylyl cyclase A and B.
P2860
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P2860
Identification and characterization of the phosphorylation sites of the guanylyl cyclase-linked natriuretic peptide receptors A and B.
description
1999 nî lūn-bûn
@nan
1999 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Identification and characteriz ...... tic peptide receptors A and B.
@ast
Identification and characteriz ...... tic peptide receptors A and B.
@en
type
label
Identification and characteriz ...... tic peptide receptors A and B.
@ast
Identification and characteriz ...... tic peptide receptors A and B.
@en
prefLabel
Identification and characteriz ...... tic peptide receptors A and B.
@ast
Identification and characteriz ...... tic peptide receptors A and B.
@en
P356
P1433
P1476
Identification and characteriz ...... tic peptide receptors A and B.
@en
P2093
P304
P356
10.1006/METH.1999.0893
P577
1999-12-01T00:00:00Z