Mice treated with chlorpyrifos or chlorpyrifos oxon have organophosphorylated tubulin in the brain and disrupted microtubule structures, suggesting a role for tubulin in neurotoxicity associated with exposure to organophosphorus agents.

Mice treated with chlorpyrifos or chlorpyrifos oxon have organophosphorylated tubulin in the brain and disrupted microtubule structures, suggesting a role for tubulin in neurotoxicity associated with exposure to organophosphorus agents.

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http://www.wikidata.org/entity/Q33792445

Q33792445

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Recent research on Gulf War Illness and other health problems in veterans of the 1991 Gulf War: effects of toxicant exposures during deployment Functional consequences of repeated organophosphate exposure: potential non-cholinergic mechanisms Protein tyrosine adduct in humans self-poisoned by chlorpyrifos Protein adducts as biomarkers of exposure to organophosphorus compounds Longitudinal assessment of chlorpyrifos exposure and effect biomarkers in adolescent Egyptian agricultural workers Diisopropylfluorophosphate Impairs the Transport of Membrane-Bound Organelles in Rat Cortical Axons Detection of adduct on tyrosine 411 of albumin in humans poisoned by dichlorvos Development of diagnostics in the search for an explanation of aerotoxic syndrome.Review of tyrosine and lysine as new motifs for organophosphate binding to proteins that have no active site serine Cresyl saligenin phosphate, an organophosphorus toxicant, makes covalent adducts with histidine, lysine, and tyrosine residues of human serum albumin Autoantibodies to nervous system-specific proteins are elevated in sera of flight crew members: biomarkers for nervous system injury.Prenatal organophosphates exposure alternates the cleavage plane orientation of apical neural progenitor in developing neocortex.Exposure to tri-o-cresyl phosphate detected in jet airplane passengers.Exposure to glyphosate- and/or Mn/Zn-ethylene-bis-dithiocarbamate-containing pesticides leads to degeneration of γ-aminobutyric acid and dopamine neurons in Caenorhabditis elegans.Effects of nickel, chlorpyrifos and their mixture on the Dictyostelium discoideum proteome Decreased reelin expression and organophosphate pesticide exposure alters mouse behaviour and brain morphology Polyclonal antibody to soman-tyrosine.A Complex Interaction Between Reduced Reelin Expression and Prenatal Organophosphate Exposure Alters Neuronal Cell Morphology.Methamidophos exposure during the early postnatal period of mice: immediate and late-emergent effects on the cholinergic and serotonergic systems and behavior.The neuronal cytoskeleton as a potential target in the developmental neurotoxicity of organophosphorothionate insecticides.Identification of protein adduction using mass spectrometry: Protein adducts as biomarkers and predictors of toxicity mechanisms.Sarin (GB, O-isopropyl methylphosphonofluoridate) neurotoxicity: critical review.Developmental neurotoxicity of the organophosphorus insecticide chlorpyrifos: from clinical findings to preclinical models and potential mechanisms.Effect of CYP2B6*6 and CYP2C19*2 genotype on chlorpyrifos metabolism.Adverse outcome pathways during early fish development: a conceptual framework for identification of chemical screening and prioritization strategies.Reprogramming cells from Gulf War veterans into neurons to study Gulf War illness.Neural autoantibodies in patients with neurological symptoms and histories of chemical/mold exposures.Pharmacologically increasing microtubule acetylation corrects stress-exacerbated effects of organophosphates on neurons.Analysis of biotinylated generation 4 poly(amidoamine) (PAMAM) dendrimer distribution in the rat brain and toxicity in a cellular model of the blood-brain barrier.Covalent binding of the organophosphate insecticide profenofos to tyrosine on α- and β-tubulin proteins.Mass Spectral Detection of Diethoxyphospho-Tyrosine Adducts on Proteins from HEK293 Cells Using Monoclonal Antibody depY for Enrichment.Blood-Brain Barrier Cellular Responses Toward Organophosphates: Natural Compensatory Processes and Exogenous Interventions to Rescue Barrier Properties

P2860

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P2860

Mice treated with chlorpyrifos or chlorpyrifos oxon have organophosphorylated tubulin in the brain and disrupted microtubule structures, suggesting a role for tubulin in neurotoxicity associated with exposure to organophosphorus agents.

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http://www.wikidata.org/entity/Q33792445

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2010 nî lūn-bûn

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2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2010 թվականի փետրվարին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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