Enzyme inhibition, polyglutamation, and the effect of LY231514 (MTA) on purine biosynthesis.
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Treatment rationale and study design for a phase III, double-blind, placebo-controlled study of maintenance pemetrexed plus best supportive care versus best supportive care immediately following induction treatment with pemetrexed plus cisplatin forThe pemetrexed-containing treatments in the non-small cell lung cancer is -/low thymidylate synthase expression better than +/high thymidylate synthase expression: a meta-analysisPhase 2 trial of pemetrexed in children and adolescents with refractory solid tumors: a Children's Oncology Group study.2,4-Diamino-5-methyl-6-substituted arylthio-furo[2,3-d]pyrimidines as novel classical and nonclassical antifolates as potential dual thymidylate synthase and dihydrofolate reductase inhibitors.Glucocorticoid receptor status is a principal determinant of variability in the sensitivity of non-small-cell lung cancer cells to pemetrexed.Clinical benefit from pemetrexed before and after crizotinib exposure and from crizotinib before and after pemetrexed exposure in patients with anaplastic lymphoma kinase-positive non-small-cell lung cancerPhase 2 trial of pemetrexed disodium and carboplatin in previously untreated extensive-stage small cell lung cancer, N0423.Association between gene expression profiles and clinical outcome of pemetrexed-based treatment in patients with advanced non-squamous non-small cell lung cancer: exploratory results from a phase II study.Chemotherapy and targeted therapies for unresectable malignant mesotheliomaReduced folate and serum vitamin metabolites in patients with rectal carcinoma: an open-label feasibility study of pemetrexed with folic acid and vitamin B12 supplementation.Dual inhibitors of thymidylate synthase and dihydrofolate reductase as antitumor agents: design, synthesis, and biological evaluation of classical and nonclassical pyrrolo[2,3-d]pyrimidine antifolates(1)Clinical effect of pemetrexed as the first-line treatment in Chinese patients with advanced anaplastic lymphoma kinase-positive non-small cell lung cancer.Phase II study of pemetrexed in patients with advanced neuroendocrine tumors.Phase II evaluation of pemetrexed in the treatment of recurrent or persistent platinum-resistant ovarian or primary peritoneal carcinoma: a study of the Gynecologic Oncology Group.Patient selection and targeted treatment in the management of platinum-resistant ovarian cancer.Parameters for individualizing systemic therapy in non-small cell lung cancerDesign, synthesis, and biological evaluation of classical and nonclassical 2-amino-4-oxo-5-substituted-6-methylpyrrolo[3,2-d]pyrimidines as dual thymidylate synthase and dihydrofolate reductase inhibitors.Potent dual thymidylate synthase and dihydrofolate reductase inhibitors: classical and nonclassical 2-amino-4-oxo-5-arylthio-substituted-6-methylthieno[2,3-d]pyrimidine antifolates.Adjuvant bidirectional chemotherapy with intraperitoneal pemetrexed combined with intravenous Cisplatin for diffuse malignant peritoneal mesothelioma.
P2860
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P2860
Enzyme inhibition, polyglutamation, and the effect of LY231514 (MTA) on purine biosynthesis.
description
1999 nî lūn-bûn
@nan
1999 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Enzyme inhibition, polyglutama ...... (MTA) on purine biosynthesis.
@ast
Enzyme inhibition, polyglutama ...... (MTA) on purine biosynthesis.
@en
type
label
Enzyme inhibition, polyglutama ...... (MTA) on purine biosynthesis.
@ast
Enzyme inhibition, polyglutama ...... (MTA) on purine biosynthesis.
@en
prefLabel
Enzyme inhibition, polyglutama ...... (MTA) on purine biosynthesis.
@ast
Enzyme inhibition, polyglutama ...... (MTA) on purine biosynthesis.
@en
P2093
P1433
P1476
Enzyme inhibition, polyglutama ...... 4 (MTA) on purine biosynthesis
@en
P2093
P433
P577
1999-04-01T00:00:00Z