The microtubule-associated histone deacetylase 6 (HDAC6) regulates epidermal growth factor receptor (EGFR) endocytic trafficking and degradation.
about
HDAC6 regulates mutant SOD1 aggregation through two SMIR motifs and tubulin acetylationExpanding proteostasis by membrane trafficking networksMolecular pathways for intracellular cholesterol accumulation: common pathogenic mechanisms in Niemann-Pick disease Type C and cystic fibrosisHistone deacetylase 6 plays a role as a distinct regulator of diverse cellular processesLoss of ALS2/Alsin exacerbates motor dysfunction in a SOD1-expressing mouse ALS model by disturbing endolysosomal traffickingUbiquitin in Influenza Virus Entry and Innate ImmunityATP13A2 and Alpha-synuclein: a Metal Taste in AutophagyRegulation of adipogenesis by cytoskeleton remodelling is facilitated by acetyltransferase MEC-17-dependent acetylation of α-tubulinA Rational Approach for the Identification of Non-Hydroxamate HDAC6-Selective InhibitorsA phase I, pharmacokinetic, and pharmacodynamic study of panobinostat, an HDAC inhibitor, combined with erlotinib in patients with advanced aerodigestive tract tumorsHistone deacetylase 6 regulates cytokinesis and erythrocyte enucleation through deacetylation of formin protein mDia2.Microtubules and their role in cellular stress in cancerHDAC inhibition decreases the expression of EGFR in colorectal cancer cells.Exploring the yeast acetylome using functional genomicsHighly dynamic microtubules improve the effectiveness of early stages of human influenza A/NWS/33 virus infection in LLC-MK2 cells.HDAC6 regulates epidermal growth factor receptor (EGFR) endocytic trafficking and degradation in renal epithelial cells.Blocking the class I histone deacetylase ameliorates renal fibrosis and inhibits renal fibroblast activation via modulating TGF-beta and EGFR signalingAcetylation of EGF receptor contributes to tumor cell resistance to histone deacetylase inhibitors.The redox basis of epigenetic modifications: from mechanisms to functional consequences.Histone deacetylase 6 is a FoxO transcription factor-dependent effector in skeletal muscle atrophy.Cytoplasmic retention of a nucleocytoplasmic protein TBC1D3 by microtubule network is required for enhanced EGFR signalingα-Tubulin acetylation elevated in metastatic and basal-like breast cancer cells promotes microtentacle formation, adhesion, and invasive migration.Navigator-3, a modulator of cell migration, may act as a suppressor of breast cancer progression.Potential non-oncological applications of histone deacetylase inhibitors.An atlas of histone deacetylase expression in breast cancer: fluorescence methodology for comparative semi-quantitative analysis.EGF-induced sodium influx regulates EGFR trafficking through HDAC6 and tubulin acetylation.Induction of c-Cbl contributes to anti-cancer effects of HDAC inhibitor in lung cancer.Electron Microscopy of Living Cells During in Situ Fluorescence MicroscopyTubulin Beta3 Serves as a Target of HDAC3 and Mediates Resistance to Microtubule-Targeting Drugs.On mammary gland growth factors: roles in normal development and in cancerHistone deacetylase 6 inhibition enhances oncolytic viral replication in glioma.The Shp2-induced epithelial disorganization defect is reversed by HDAC6 inhibition independent of Cdc42Regulation of CD133 by HDAC6 promotes β-catenin signaling to suppress cancer cell differentiationMonoubiquitination of filamin B regulates vascular endothelial growth factor-mediated trafficking of histone deacetylase 7.HDAC6 and ovarian cancer.MIIP accelerates epidermal growth factor receptor protein turnover and attenuates proliferation in non-small cell lung cancer.HDAC6 activity is not required for basal autophagic flux in metastatic prostate cancer cells.Syntaxin 6-mediated Golgi translocation plays an important role in nuclear functions of EGFR through microtubule-dependent trafficking.Phase 1 study of romidepsin plus erlotinib in advanced non-small cell lung cancer.G Protein-coupled Receptor Kinase 2 (GRK2) Promotes Breast Tumorigenesis Through a HDAC6-Pin1 Axis
P2860
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P2860
The microtubule-associated histone deacetylase 6 (HDAC6) regulates epidermal growth factor receptor (EGFR) endocytic trafficking and degradation.
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
The microtubule-associated his ...... c trafficking and degradation.
@ast
The microtubule-associated his ...... c trafficking and degradation.
@en
type
label
The microtubule-associated his ...... c trafficking and degradation.
@ast
The microtubule-associated his ...... c trafficking and degradation.
@en
prefLabel
The microtubule-associated his ...... c trafficking and degradation.
@ast
The microtubule-associated his ...... c trafficking and degradation.
@en
P2093
P2860
P356
P1476
The microtubule-associated his ...... c trafficking and degradation.
@en
P2093
Charlotte C Hubbert
Tso-Pang Yao
Ya-sheng Gao
P2860
P304
11219-11226
P356
10.1074/JBC.M109.042754
P407
P577
2010-02-04T00:00:00Z