Rta of murine gammaherpesvirus 68 reactivates the complete lytic cycle from latency.
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Interplay of Murine Gammaherpesvirus 68 with NF-kappaB Signaling of the HostMurine gammaherpesvirus 68 encoding open reading frame 11 targets TANK binding kinase 1 to negatively regulate the host type I interferon responseTpl2/AP-1 enhances murine gammaherpesvirus 68 lytic replication.Systematic identification of cellular signals reactivating Kaposi sarcoma-associated herpesvirus.High-resolution functional profiling of a gammaherpesvirus RTA locus in the context of the viral genomeRTA promoter demethylation and histone acetylation regulation of murine gammaherpesvirus 68 reactivationMolecular biology of KSHV in relation to AIDS-associated oncogenesis.An in vitro system for studying murid herpesvirus-4 latency and reactivation.A gammaherpesvirus complement regulatory protein promotes initiation of infection by activation of protein kinase Akt/PKB.Induction of protective immunity against murine gammaherpesvirus 68 infection in the absence of viral latency.Ex vivo stimulation of B cells latently infected with gammaherpesvirus 68 triggers reactivation from latencyMurine gammaherpesvirus 68 has evolved gamma interferon and stat1-repressible promoters for the lytic switch gene 50.Interferon regulatory factor 1 restricts gammaherpesvirus replication in primary immune cells.Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 RTA reactivates murine gammaherpesvirus 68 from latency.Transcription activation of polyadenylated nuclear rna by rta in human herpesvirus 8/Kaposi's sarcoma-associated herpesvirus.Kinetics of murine gammaherpesvirus 68 gene expression following infection of murine cells in culture and in mice.Activation of NF-κB via endosomal Toll-like receptor 7 (TLR7) or TLR9 suppresses murine herpesvirus 68 reactivation.Gamma interferon blocks gammaherpesvirus reactivation from latency.Histone deacetylases and the nuclear receptor corepressor regulate lytic-latent switch gene 50 in murine gammaherpesvirus 68-infected macrophagesA gammaherpesvirus 68 gene 50 null mutant establishes long-term latency in the lung but fails to vaccinate against a wild-type virus challenge.Disruption of the M2 gene of murine gammaherpesvirus 68 alters splenic latency following intranasal, but not intraperitoneal, inoculation.Characterization of interactions between RTA and the promoter of polyadenylated nuclear RNA in Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8.Gammaherpesvirus lytic gene expression as characterized by DNA array.Kinetics of expression of rhesus monkey rhadinovirus (RRV) and identification and characterization of a polycistronic transcript encoding the RRV Orf50/Rta, RRV R8, and R8.1 genes.Construction and characterization of an infectious murine gammaherpesivrus-68 bacterial artificial chromosome.Disruption of gammaherpesvirus 68 gene 50 demonstrates that Rta is essential for virus replication.The latency-associated nuclear antigen homolog of herpesvirus saimiri inhibits lytic virus replication.ORF18 is a transfactor that is essential for late gene transcription of a gammaherpesvirus.In vivo activation of toll-like receptor-9 induces an age-dependent abortive lytic cycle reactivation of murine gammaherpesvirus-68.Quantitative analysis of long-term virus-specific CD8+-T-cell memory in mice challenged with unrelated pathogensSelective gene expression of latent murine gammaherpesvirus 68 in B lymphocytes.NF-kappaB inhibits gammaherpesvirus lytic replicationGammaherpesvirus gene expression and DNA synthesis are facilitated by viral protein kinase and histone variant H2AX.Murine Gammaherpesvirus 68 ORF48 Is an RTA-Responsive Gene Product and Functions in both Viral Lytic Replication and Latency during In Vivo Infection.The virion-associated open reading frame 49 of murine gammaherpesvirus 68 promotes viral replication both in vitro and in vivo as a derepressor of RTA.Distinct domains in ORF52 tegument protein mediate essential functions in murine gammaherpesvirus 68 virion tegumentation and secondary envelopmentSystematic identification of type I and type II interferon-induced antiviral factors.Tiled microarray identification of novel viral transcript structures and distinct transcriptional profiles during two modes of productive murine gammaherpesvirus 68 infection.Murine gammaherpesvirus 68 ORF52 encodes a tegument protein required for virion morphogenesis in the cytoplasm.Infection-Induced Retrotransposon-Derived Noncoding RNAs Enhance Herpesviral Gene Expression via the NF-κB Pathway
P2860
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P2860
Rta of murine gammaherpesvirus 68 reactivates the complete lytic cycle from latency.
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Rta of murine gammaherpesvirus 68 reactivates the complete lytic cycle from latency.
@ast
Rta of murine gammaherpesvirus 68 reactivates the complete lytic cycle from latency.
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type
label
Rta of murine gammaherpesvirus 68 reactivates the complete lytic cycle from latency.
@ast
Rta of murine gammaherpesvirus 68 reactivates the complete lytic cycle from latency.
@en
prefLabel
Rta of murine gammaherpesvirus 68 reactivates the complete lytic cycle from latency.
@ast
Rta of murine gammaherpesvirus 68 reactivates the complete lytic cycle from latency.
@en
P2093
P2860
P1433
P1476
Rta of murine gammaherpesvirus 68 reactivates the complete lytic cycle from latency
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P2093
P2860
P304
P356
10.1128/JVI.74.8.3659-3667.2000
P577
2000-04-01T00:00:00Z