Metformin impairs growth of endometrial cancer cells via cell cycle arrest and concomitant autophagy and apoptosis. - Wikidata - wikimedia - TriplyDB

Metformin impairs growth of endometrial cancer cells via cell cycle arrest and concomitant autophagy and apoptosis.

Metformin impairs growth of endometrial cancer cells via cell cycle arrest and concomitant autophagy and apoptosis.

http://www.wikidata.org/entity/Q33804513

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Old drug, new trick: repurposing metformin for gynecologic cancers?Hyperglycemia as a risk factor for cancer progression Metformin disrupts malignant behavior of oral squamous cell carcinoma via a novel signaling involving Late SV40 factor/Aurora-A.Metformin increases degradation of phospholamban via autophagy in cardiomyocytes Clinical benefits of metformin in gynecologic oncology.Juglone exerts antitumor effect in ovarian cancer cells.Metformin combined with aspirin significantly inhibit pancreatic cancer cell growth in vitro and in vivo by suppressing anti-apoptotic proteins Mcl-1 and Bcl-2 Metformin Promotes Apoptosis but Suppresses Autophagy in Glucose-Deprived H4IIE Hepatocellular Carcinoma Cells.Metformin inhibits salivary adenocarcinoma growth through cell cycle arrest and apoptosis Obesity and Cancer: An Angiogenic and Inflammatory Link.Metformin inhibits 17β-estradiol-induced epithelial-to-mesenchymal transition via βKlotho-related ERK1/2 signaling and AMPKα signaling in endometrial adenocarcinoma cells Metformin represses bladder cancer progression by inhibiting stem cell repopulation via COX2/PGE2/STAT3 axis.Proliferation and metastatic potential of endometrial cancer cells in response to metformin treatment in a high versus normal glucose environment.New insight for metformin against bladder cancer.Metformin Elicits Antitumor Effects and Downregulates the Histone Methyltransferase Multiple Myeloma SET Domain (MMSET) in Prostate Cancer Cells.Metformin in pancreatic cancer treatment: from clinical trials through basic research to biomarker quantification.Glucose-deprivation increases thyroid cancer cells sensitivity to metformin.Combination simvastatin and metformin induces G1-phase cell cycle arrest and Ripk1- and Ripk3-dependent necrosis in C4-2B osseous metastatic castration-resistant prostate cancer cells.Therapeutic Implications of Autophagy Inducers in Immunological Disorders, Infection, and Cancer.Escin reduces cell proliferation and induces apoptosis on glioma and lung adenocarcinoma cell lines.Induction of apoptosis by metformin and progesterone in estrogen-induced endometrial hyperplasia in rats: involvement of the bcl-2 family proteins.Simvastatin and metformin inhibit cell growth in hepatitis C virus infected cells via mTOR increasing PTEN and autophagy.Metformin as an anti-cancer agent: actions and mechanisms targeting cancer stem cells.Metformin targeting autophagy overcomes progesterone resistance in endometrial carcinoma.Metformin as a Therapeutic Target in Endometrial Cancers Metabolic Profiles Associated With Metformin Efficacy in Cancer Pleiotropic Effects of Metformin on Cancer

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P2860

Metformin impairs growth of endometrial cancer cells via cell cycle arrest and concomitant autophagy and apoptosis.

http://www.wikidata.org/entity/Q33804513

description

2014 nî lūn-bûn

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2014 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2014 թվականի հունիսին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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Metformin impairs growth of en ...... itant autophagy and apoptosis.

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Metformin impairs growth of en ...... itant autophagy and apoptosis.

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Metformin impairs growth of en ...... itant autophagy and apoptosis.

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Metformin impairs growth of en ...... itant autophagy and apoptosis.

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Cancer Cell International

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P2093

Akie Takebayashi

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Akimasa Takahashi

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Akiyoshi Yamanaka

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Fuminori Kimura

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Kentaro Takahashi

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Nobuyuki Kita

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Takashi Murakami

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P2860

Metformin in Cancer Therapy: A New Perspective for an Old Antidiabetic Drug?

Cellular and molecular mechanisms of metformin: an overview

Cancer statistics, 2012

Autophagy fights disease through cellular self-digestion

Metformin induces unique biological and molecular responses in triple negative breast cancer cells

Self-eating and self-killing: crosstalk between autophagy and apoptosis

Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma

A novel response of cancer cells to radiation involves autophagy and formation of acidic vesicles.

Endometrial cancer in women 40 years old or younger.

In vitro and in vivo anti-tumor effect of metformin as a novel therapeutic agent in human oral squamous cell carcinoma.

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