Synthesis and evaluation of candidate PET radioligands for corticotropin-releasing factor type-1 receptors - Wikidata - wikimedia - TriplyDB

Synthesis and evaluation of candidate PET radioligands for corticotropin-releasing factor type-1 receptors

Synthesis and evaluation of candidate PET radioligands for corticotropin-releasing factor type-1 receptors

http://www.wikidata.org/entity/Q33810560

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Don't stress about CRF: assessing the translational failures of CRF1antagonists.Synthesis, F-18 radiolabeling, and microPET evaluation of 3-(2,4-dichlorophenyl)-N-alkyl-N-fluoroalkyl-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-amines as ligands of the corticotropin-releasing factor type-1 (CRF1) receptor.Failed PET Application Attempts in the Past, Can We Avoid Them in the Future?The CRF System as a Therapeutic Target for Neuropsychiatric Disorders.Synthesis, binding affinity, radiolabeling, and microPET evaluation of 4-(2-substituted-4-substituted)-8-(dialkylamino)-6-methyl-1-substituted-3,4-dihydropyrido[2,3-b]pyrazin-2(1H)-ones as ligands for brain corticotropin-releasing factor type-1 (CRF Fluorine-18 labelled building blocks for PET tracer synthesis.Imaging corticotropin-releasing-factor and nociceptin in addiction and PTSD models.

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Synthesis and evaluation of candidate PET radioligands for corticotropin-releasing factor type-1 receptors

http://www.wikidata.org/entity/Q33810560

description

2014 nî lūn-bûn

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2014 թուականի Մարտին հրատարակուած գիտական յօդուած

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2014 թվականի մարտին հրատարակված գիտական հոդված

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2014年の論文

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2014年学术文章

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2014年学术文章

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2014年学术文章

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2014年学术文章

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2014年学术文章

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2014年學術文章

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Synthesis and evaluation of ca ...... easing factor type-1 receptors

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Synthesis and evaluation of ca ...... easing factor type-1 receptors

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Synthesis and evaluation of ca ...... easing factor type-1 receptors

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Synthesis and evaluation of ca ...... easing factor type-1 receptors

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Synthesis and evaluation of ca ...... easing factor type-1 receptors

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J.NUCMEDBIO.2014.03.005

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Nuclear Medicine and Biology

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Synthesis and evaluation of ca ...... easing factor type-1 receptors

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Douglas D Dischino

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Frederick T Chin

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Heidi Dulac

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Jeffrey A Deskus

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Joanne J Bronson

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John E Macor

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Masahiro Fujita

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Masao Imaizumi

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Nicholas J Lodge

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Rick Pieschl

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Behavioral, biological, and chemical perspectives on targeting CRF(1) receptor antagonists to treat alcoholism.

Therapeutic utility of non-peptidic CRF1 receptor antagonists in anxiety, depression, and stress-related disorders: evidence from animal models

CRF receptor blockade prevents initiation and consolidation of stress effects on affect in the predator stress model of PTSD

Receptor occupancy of nonpeptide corticotropin-releasing factor 1 antagonist DMP696: correlation with drug exposure and anxiolytic efficacy.

PET radiotracers: crossing the blood-brain barrier and surviving metabolism

Multicenter, randomized, double-blind, active comparator and placebo-controlled trial of a corticotropin-releasing factor receptor-1 antagonist in generalized anxiety disorder.

Impaired stress response and reduced anxiety in mice lacking a functional corticotropin-releasing hormone receptor 1.

Nibbling at CRF receptor control of feeding and gastrocolonic motility.

Corticotropin-releasing factor signaling and visceral response to stress.

Quantitative pharmacological analysis of antagonist binding kinetics at CRF1 receptors in vitro and in vivo

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524-535

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scholarly article

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10.1016/J.NUCMEDBIO.2014.03.005

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6

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41

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2014-03-29T00:00:00Z

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24793011

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4072041

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