The ubiquitin proteasome system in human cardiomyopathies and heart failure.
about
Regulation of cardiac proteasomes by ubiquitination, SUMOylation, and beyondProteotoxicity: an underappreciated pathology in cardiac diseaseA large dataset of protein dynamics in the mammalian heart proteomeProteasomal and lysosomal protein degradation and heart disease.Autophagic-lysosomal inhibition compromises ubiquitin-proteasome system performance in a p62 dependent manner in cardiomyocytesDegradation of a connexin40 mutant linked to atrial fibrillation is accelerated.Roles for ATF6 and the sarco/endoplasmic reticulum protein quality control system in the heart.The interplay between autophagy and the ubiquitin-proteasome system in cardiac proteotoxicityMulticolor monitoring of the proteasome's catalytic signature.bFGF regulates autophagy and ubiquitinated protein accumulation induced by myocardial ischemia/reperfusion via the activation of the PI3K/Akt/mTOR pathway.The COP9 signalosome and cullin-RING ligases in the heartTherapeutic landscape of carfilzomib and other modulators of the ubiquitin-proteasome pathway.Transcriptional activation of muscle atrophy promotes cardiac muscle remodeling during mammalian hibernation.Gambogic acid suppresses pressure overload cardiac hypertrophy in rats.The COP9 signalosome is required for autophagy, proteasome-mediated proteolysis, and cardiomyocyte survival in adult mice.Delineation of Molecular Pathways Involved in Cardiomyopathies Caused by Troponin T MutationsNerve growth factor-induced Akt/mTOR activation protects the ischemic heart via restoring autophagic flux and attenuating ubiquitinated protein accumulation.HSP70: therapeutic potential in acute and chronic cardiac disease settings.Proteasome dysfunction in cardiomyopathies.The Role of Cardiac Myosin Binding Protein C3 in Hypertrophic Cardiomyopathy-Progress and Novel Therapeutic Opportunities.Proteostasis in cardiac health and disease.Association of LIM Domain 7 Gene Polymorphisms and Plasma Levels of LIM Domain 7 with Dilated Cardiomyopathy in a Chinese Population.Repeated intermittent administration of a ubiquitous proteasome inhibitor leads to restrictive cardiomyopathy.GSK-3β heterozygous knockout is cardioprotective in a knockin mouse model of familial dilated cardiomyopathy.Phospholamban Is Downregulated by pVHL-Mediated Degradation through Oxidative Stress in Failing Heart.Cardiac-specific ablation of the E3 ubiquitin ligase Mdm2 leads to oxidative stress, broad mitochondrial deficiency and early death.Expression of nuclear factor of activated T cells (NFAT) and downstream muscle-specific proteins in ground squirrel skeletal and heart muscle during hibernation.Understanding Key Mechanisms of Exercise-Induced Cardiac Protection to Mitigate Disease: Current Knowledge and Emerging Concepts.
P2860
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P2860
The ubiquitin proteasome system in human cardiomyopathies and heart failure.
description
2013 nî lūn-bûn
@nan
2013 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի մարտին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
The ubiquitin proteasome system in human cardiomyopathies and heart failure.
@ast
The ubiquitin proteasome system in human cardiomyopathies and heart failure.
@en
type
label
The ubiquitin proteasome system in human cardiomyopathies and heart failure.
@ast
The ubiquitin proteasome system in human cardiomyopathies and heart failure.
@en
prefLabel
The ubiquitin proteasome system in human cardiomyopathies and heart failure.
@ast
The ubiquitin proteasome system in human cardiomyopathies and heart failure.
@en
P2860
P1476
The ubiquitin proteasome system in human cardiomyopathies and heart failure.
@en
P2093
Sharlene M Day
P2860
P304
P356
10.1152/AJPHEART.00249.2012
P577
2013-03-11T00:00:00Z