Inflammatory T cell responses rely on amino acid transporter ASCT2 facilitation of glutamine uptake and mTORC1 kinase activation.
about
Clinical significance of T cell metabolic reprogramming in cancerUbiquitin signaling in immune responsesMetabolic communication in tumors: a new layer of immunoregulation for immune evasionSignaling in T cells - is anything the m(a)TOR with the picture(s)?The paracaspase MALT1: biological function and potential for therapeutic inhibitionMetabolic regulation of T cell differentiation and functionT cell metabolism drives immunityNovel therapeutic targets of tumor metabolismImmunometabolism of regulatory T cellsThe role of Fatty Acid oxidation in the metabolic reprograming of activated t-cellsTCR signaling to NF-κB and mTORC1: Expanding roles of the CARMA1 complexMALT1 is not alone after all: identification of novel paracaspasesMacrophage ABHD5 promotes colorectal cancer growth by suppressing spermidine production by SRMTargeting ASCT2-mediated glutamine uptake blocks prostate cancer growth and tumour developmentCell Surface Proteomic Map of HIV Infection Reveals Antagonism of Amino Acid Metabolism by Vpu and Nef.ASCT2 (SLC1A5)-Deficient Mice Have Normal B-Cell Development, Proliferation, and Antibody Production.Mitochondrial dysregulation and glycolytic insufficiency functionally impair CD8 T cells infiltrating human renal cell carcinoma.PET Tracer 18F-Fluciclovine Can Detect Histologically Proven Bone Metastatic Lesions: A Preclinical Study in Rat Osteolytic and Osteoblastic Bone Metastasis Models.Metabolic reprogramming towards aerobic glycolysis correlates with greater proliferative ability and resistance to metabolic inhibition in CD8 versus CD4 T cells.Nutrient Sensing via mTOR in T Cells Maintains a Tolerogenic Microenvironment.Attacking the supply wagons to starve cancer cells to death.Leucine Metabolism in T Cell Activation: mTOR Signaling and Beyond.mTOR signaling, Tregs and immune modulation.mTOR Links Environmental Signals to T Cell Fate Decisions.T-cell metabolism in autoimmune disease.T cell metabolic fitness in antitumor immunity.mTOR and metabolic regulation of conventional and regulatory T cells.T cell development involves TRAF3IP3-mediated ERK signaling in the Golgi.Targeting glutamine metabolism rescues mice from late-stage cerebral malaria.Preventing Allograft Rejection by Targeting Immune Metabolism.High expression of Solute Carrier Family 1, member 5 (SLC1A5) is associated with poor prognosis in clear-cell renal cell carcinomaSleeping Beauty Transposon Mutagenesis as a Tool for Gene Discovery in the NOD Mouse Model of Type 1 DiabetesThe cytotoxic T cell proteome and its shaping by the kinase mTOR.Cell surface Glut1 levels distinguish human CD4 and CD8 T lymphocyte subsets with distinct effector functions.Amino acid auxotrophy as a system of immunological control nodes.Glucose and glutamine fuel protein O-GlcNAcylation to control T cell self-renewal and malignancy.Diet-dependent, microbiota-independent regulation of IL-10-producing lamina propria macrophages in the small intestine.Metabolomics connects aberrant bioenergetic, transmethylation, and gut microbiota in sarcoidosis.Nutrient and Metabolic Sensing in T Cell Responses.Roles of Dietary Amino Acids and Their Metabolites in Pathogenesis of Inflammatory Bowel Disease.
P2860
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P2860
Inflammatory T cell responses rely on amino acid transporter ASCT2 facilitation of glutamine uptake and mTORC1 kinase activation.
description
2014 nî lūn-bûn
@nan
2014 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Inflammatory T cell responses ...... and mTORC1 kinase activation.
@ast
Inflammatory T cell responses ...... and mTORC1 kinase activation.
@en
type
label
Inflammatory T cell responses ...... and mTORC1 kinase activation.
@ast
Inflammatory T cell responses ...... and mTORC1 kinase activation.
@en
prefLabel
Inflammatory T cell responses ...... and mTORC1 kinase activation.
@ast
Inflammatory T cell responses ...... and mTORC1 kinase activation.
@en
P2093
P2860
P1433
P1476
Inflammatory T cell responses ...... and mTORC1 kinase activation.
@en
P2093
Jae-Hoon Chang
Mako Nakaya
Mikyoung Chang
Shao-Cong Sun
Xiaofei Zhou
Xuhong Cheng
Yichuan Xiao
P2860
P304
P356
10.1016/J.IMMUNI.2014.04.007
P407
P577
2014-05-01T00:00:00Z