Caspase-8 acts as a molecular rheostat to limit RIPK1- and MyD88-mediated dendritic cell activation - Wikidata - wikimedia - TriplyDB

Caspase-8 acts as a molecular rheostat to limit RIPK1- and MyD88-mediated dendritic cell activation

Caspase-8 acts as a molecular rheostat to limit RIPK1- and MyD88-mediated dendritic cell activation

http://www.wikidata.org/entity/Q33819040

about

Converging roles of caspases in inflammasome activation, cell death and innate immunity Caspase-8 Deficiency Presenting as Late-Onset Multi-Organ Lymphocytic Infiltration with Granulomas in two Adult Siblings Structure guided design of potent and selective ponatinib-based hybrid inhibitors for RIPK1.Caspase-8 as an Effector and Regulator of NLRP3 Inflammasome Signaling Activity of Uncleaved Caspase-8 Controls Anti-bacterial Immune Defense and TLR-Induced Cytokine Production Independent of Cell Death Conditional deletion of caspase-8 in macrophages alters macrophage activation in a RIPK-dependent manner.New insights into the regulation of innate immunity by caspase-8.RIPK1 and RIPK3 Kinases Promote Cell-Death-Independent Inflammation by Toll-like Receptor 4.Caspase-8: not so silently deadly.The inflammatory role of phagocyte apoptotic pathways in rheumatic diseases.Novel roles for caspase-8 in IL-1β and inflammasome regulation.Emerging Roles for RIPK1 and RIPK3 in Pathogen-Induced Cell Death and Host Immunity.Functions of Murine Dendritic Cells.The contribution of the programmed cell death machinery in innate immune cells to lupus nephritis.Caspase-8: regulating life and death.Caspases control antiviral innate immunity.The caspase-8/RIPK3 signaling axis in antigen presenting cells controls the inflammatory arthritic response.Deletion of caspase-8 in mouse myeloid cells blocks microglia pro-inflammatory activation and confers protection in MPTP neurodegeneration model.Bim suppresses the development of SLE by limiting myeloid inflammatory responses.The Effects of Dendritic Cell Hypersensitivity on Persistent Viral Infection.Monocyte-derived alveolar macrophages drive lung fibrosis and persist in the lung over the life span.Dendritic Cell RIPK1 Maintains Immune Homeostasis by Preventing Inflammation and Autoimmunity.Caspase-8 deficiency in mouse embryos triggers chronic RIPK1-dependent activation of inflammatory genes, independently of RIPK3.

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P2860

Caspase-8 acts as a molecular rheostat to limit RIPK1- and MyD88-mediated dendritic cell activation

http://www.wikidata.org/entity/Q33819040

description

2014 nî lūn-bûn

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2014 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի մայիսին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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name

Caspase-8 acts as a molecular ...... ated dendritic cell activation

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Caspase-8 acts as a molecular ...... ated dendritic cell activation

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Caspase-8 acts as a molecular ...... ated dendritic cell activation

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Caspase-8 acts as a molecular ...... ated dendritic cell activation

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JIMMUNOL.1400122

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Journal of Immunology

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Caspase-8 acts as a molecular ...... ated dendritic cell activation

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P2093

Angelica K Gierut

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Chandra Mohan

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Christian Stehlik

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G Kenneth Haines

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G Scott Budinger

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Harris Perlman

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Rana Saber

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Stephen M Hedrick

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P2860

Dynamic regulation of neutrophil survival through tyrosine phosphorylation or dephosphorylation of caspase-8

cIAPs block Ripoptosome formation, a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoforms

The IRF family, revisited

Viral infection and the evolution of caspase 8-regulated apoptotic and necrotic death pathways

Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis

Mechanisms of necroptosis in T cells

RIP3 mediates the embryonic lethality of caspase-8-deficient mice

BH3-only proteins in rheumatoid arthritis: potential targets for therapeutic intervention.

Activation of NF-kappaB by FADD, Casper, and caspase-8.

Microbiota and autoimmune disease: the hosted self.

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5548-5560

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scholarly article

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10.4049/JIMMUNOL.1400122

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12

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192

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Alexander V. Misharin

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2014-05-07T00:00:00Z

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24808358

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4074511

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