A theory for the proton transport of the influenza virus M2 protein: extensive test against conductance data
about
M2 protein from influenza A: from multiple structures to biophysical and functional insightsPhilosophy of voltage-gated proton channelsVoltage-gated proton channels: molecular biology, physiology, and pathophysiology of the H(V) familyModeling the membrane environment has implications for membrane protein structure and function: influenza A M2 protein.Theoretical frameworks for multiscale modeling and simulationMultiscale simulation reveals a multifaceted mechanism of proton permeation through the influenza A M2 proton channel.2D IR spectroscopy reveals the role of water in the binding of channel-blocking drugs to the influenza M2 channel.NMR detection of pH-dependent histidine-water proton exchange reveals the conduction mechanism of a transmembrane proton channel.Equivalence of two approaches for modeling ion permeation through a transmembrane channel with an internal binding siteEffect of cytosolic pH on inward currents reveals structural characteristics of the proton transport cycle in the influenza A protein M2 in cell-free membrane patches of Xenopus oocytesTheory and simulation of diffusion-influenced, stochastically gated ligand binding to buried sites.M2 proton channel structural validation from full-length protein samples in synthetic bilayers and E. coli membranes.Dynamic Short Hydrogen Bonds in Histidine Tetrad of Full-Length M2 Proton Channel Reveal Tetrameric Structural Heterogeneity and Functional MechanismRole of diffusion in the kinetics of reversible enzyme-catalyzed reactions.Ion efflux and influenza infection trigger NLRP3 inflammasome signaling in human dendritic cellsAb initio calculations and validation of the pH-dependent structures of the His37-Trp41 quartet, the heart of acid activation and proton conductance in the M2 protein of Influenza A virusAcid activation mechanism of the influenza A M2 proton channel.Asp44 stabilizes the Trp41 gate of the M2 proton channel of influenza A virus.Mechanistic insight into the h(2)o/d (2)o isotope effect in the proton transport of the influenza virus m2 protein.Activation pH and Gating Dynamics of Influenza A M2 Proton Channel Revealed by Single-Molecule Spectroscopy.Infrared and fluorescence assessment of the hydration status of the tryptophan gate in the influenza A M2 proton channel.Mechanistic insights from functional characterization of an unnatural His37 mutant of the influenza A/M2 protein.Mechanism-Based Mathematical Model for Gating of Ionotropic Glutamate Receptors.Fractional Poisson-Nernst-Planck Model for Ion Channels I: Basic Formulations and Algorithms.
P2860
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P2860
A theory for the proton transport of the influenza virus M2 protein: extensive test against conductance data
description
2011 nî lūn-bûn
@nan
2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
A theory for the proton transp ...... test against conductance data
@ast
A theory for the proton transp ...... test against conductance data
@en
type
label
A theory for the proton transp ...... test against conductance data
@ast
A theory for the proton transp ...... test against conductance data
@en
prefLabel
A theory for the proton transp ...... test against conductance data
@ast
A theory for the proton transp ...... test against conductance data
@en
P2860
P1433
P1476
A theory for the proton transp ...... test against conductance data
@en
P2860
P304
P356
10.1016/J.BPJ.2011.01.002
P407
P577
2011-02-01T00:00:00Z