Elongational flow induces the unfolding of von Willebrand factor at physiological flow rates.
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A pH-regulated dimeric bouquet in the structure of von Willebrand factorThe unfolded von Willebrand factor response in bloodstream: the self-association perspectiveStudy of blood flow in several benchmark micro-channels using a two-fluid approach.Cooperation within von Willebrand factors enhances adsorption mechanism.Calcium modulates force sensing by the von Willebrand factor A2 domainA General Shear-Dependent Model for Thrombus FormationAtherosclerotic geometries exacerbate pathological thrombus formation poststenosis in a von Willebrand factor-dependent manner.von Willebrand factor, Jedi knight of the bloodstreamForce-induced on-rate switching and modulation by mutations in gain-of-function von Willebrand diseases.Shear stress-induced unfolding of VWF accelerates oxidation of key methionine residues in the A1A2A3 region.Force sensing by the vascular protein von Willebrand factor is tuned by a strong intermonomer interaction.Direct observation of von Willebrand factor elongation and fiber formation on collagen during acute whole blood exposure to pathological flow.Systems Analysis of Thrombus Formation.Biology and physics of von Willebrand factor concatamers.Fluid Mechanics of Blood Clot Formation.Inducing protein aggregation by extensional flow.Multiscale simulation of molecular processes in cellular environments.A biophysical view on von Willebrand factor activation.pH-Dependent Interactions in Dimers Govern the Mechanics and Structure of von Willebrand FactorInternal tension in a collapsed polymer under shear flow and the connection to enzymatic cleavage of von Willebrand factor.Force-sensitive autoinhibition of the von Willebrand factor is mediated by interdomain interactionsVon Willlebrand adhesion to surfaces at high shear rates is controlled by long-lived bondsConstricted microfluidic devices to study the effects of transient high shear exposure on platelets.Receptor-mediated cell mechanosensing.A bio-inspired method for direct measurement of local wall shear rates with micrometer localization using the multimeric protein von Willebrand factor as sensor molecule.An iterative method for hydrodynamic interactions in Brownian dynamics simulations of polymer dynamics.Application of a strain rate gradient microfluidic device to von Willebrand's disease screening.Micromechanical model for isolated polymer-colloid clusters under tension.Dynamics of collapsed polymers under the simultaneous influence of elongational and shear flows.14-3-3 proteins in platelet biology and glycoprotein Ib-IX signaling.Optimization of flow-focusing devices for homogeneous extensional flowPhysical degradation of proteins in well-defined fluid flows studied within a four-roll apparatus
P2860
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P2860
Elongational flow induces the unfolding of von Willebrand factor at physiological flow rates.
description
2010 nî lūn-bûn
@nan
2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
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2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
name
Elongational flow induces the ...... r at physiological flow rates.
@ast
Elongational flow induces the ...... r at physiological flow rates.
@en
type
label
Elongational flow induces the ...... r at physiological flow rates.
@ast
Elongational flow induces the ...... r at physiological flow rates.
@en
prefLabel
Elongational flow induces the ...... r at physiological flow rates.
@ast
Elongational flow induces the ...... r at physiological flow rates.
@en
P2860
P1433
P1476
Elongational flow induces the ...... r at physiological flow rates.
@en
P2093
Alfredo Alexander-Katz
Charles E Sing
P2860
P356
10.1016/J.BPJ.2010.01.032
P407
P577
2010-05-01T00:00:00Z