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Current status of xenotransplantation and prospects for clinical application

Current status of xenotransplantation and prospects for clinical application

http://www.wikidata.org/entity/Q33835678

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Clinical lung xenotransplantation--what donor genetic modifications may be necessary?Four-dimensional characterization of thrombosis in a live-cell, shear-flow assay: development and application to xenotransplantation Controlling coagulation dysregulation in xenotransplantation.Chimeric 2C10R4 anti-CD40 antibody therapy is critical for long-term survival of GTKO.hCD46.hTBM pig-to-primate cardiac xenograft Expression of human CD46 modulates inflammation associated with GalTKO lung xenograft injury Development of a consensus protocol to quantify primate anti-non-Gal xenoreactive antibodies using pig aortic endothelial cells Alternative immunomodulatory strategies for xenotransplantation: CD80/CD86-CTLA4 pathway-modified immature dendritic cells promote xenograft survival.Epigenetic changes of lentiviral transgenes in porcine stem cells derived from embryonic origin.Complement inhibition in a xenogeneic model of interactions between human whole blood and porcine endothelium Islet xenotransplantation using gal-deficient neonatal donors improves engraftment and function.On the intersections of basic and applied research in xenotransplantation.Porcine models of digestive disease: the future of large animal translational research.Infection barriers to successful xenotransplantation focusing on porcine endogenous retroviruses.Complete absence of the αGal xenoantigen and isoglobotrihexosylceramide in α1,3galactosyltransferase knock-out pigs.Microencapsulated cell tracking.Construction and characterization of an infectious replication competent clone of porcine endogenous retrovirus from Chinese miniature pigs The effect of Gal expression on pig cells on the human T-cell xenoresponse.Xenotransplantation--the future of corneal transplantation?Xenotransplantation: from the lab to the clinic: Sunrise Symposium at the XXIII International Congress of the Transplantation Society, Vancouver, Canada, August 2010.The usefulness and limitations of the diabetic macaque model in evaluating long-term porcine islet xenograft survival.New concepts of immune modulation in xenotransplantation.Lung xenotransplantation: recent progress and current status.Current status of pig kidney xenotransplantation Lung xenotransplantation: a review Complement C3 inhibitor Cp40 attenuates xenoreactions in pig hearts perfused with human blood.Comparison of porcine endogenous retroviruses infectious potential in supernatants of producer cells and in cocultures.Level of acceptance of solid organ xenotransplantation among personnel in Spanish, Mexican, and Cuban hospitals.Absence of Gal epitope prolongs survival of swine lungs in an ex vivo model of hyperacute rejection.T-cell-based immunosuppressive therapy inhibits the development of natural antibodies in infant baboons.Xenogeneic lung transplantation models.Porcine endogenous retrovirus copy number in different pig breeds is not related to genetic diversity.Microbiological safety of porcine islets: comparison with source pig.The Role of NK Cells in Pig-to-Human Xenotransplantation.Blockade of CD40-CD154 costimulatory pathway promotes long-term survival of full-thickness porcine corneal grafts in nonhuman primates: clinically applicable xenocorneal transplantation.Evaluation of submucosally injected polyethylene glycol-based hydrogel and bovine cross-linked collagen in the canine urethra using cystoscopy, magnetic resonance imaging and histopathology.The production of UL16-binding protein 1 targeted pigs using CRISPR technology.Absence of interaction between porcine endogenous retrovirus and porcine cytomegalovirus in pig-to-baboon renal xenotransplantation in vivo.Porcine CTLA4-Ig prolong islet xenografts in rats by downregulating the direct pathway of T-cell activation.Immunological Compatibility of Bone Tissues from Alpha-1,3-galactosyltransferase Knockout Pig for Xenotransplantation.Relative efficiency of porcine and human cytotoxic T-lymphocyte antigen 4 immunoglobulin in inhibiting human CD4+ T-cell responses co-stimulated by porcine and human B7 molecules

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Current status of xenotransplantation and prospects for clinical application

http://www.wikidata.org/entity/Q33835678

description

2009 nî lūn-bûn

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2009 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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Current status of xenotransplantation and prospects for clinical application

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Current status of xenotransplantation and prospects for clinical application

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Current status of xenotransplantation and prospects for clinical application

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Current status of xenotransplantation and prospects for clinical application

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Current status of xenotransplantation and prospects for clinical application

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J.1399-3089.2009.00534.X

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Xenotransplantation

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Current status of xenotransplantation and prospects for clinical application

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P2093

Anthony Dorling

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Bernhard J Hering

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David Ayares

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David K C Cooper

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Jay A Fishman

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Jörg D Seebach

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Michael A Rees

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Richard N Pierson

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P2860

Increased immunosuppression, not anticoagulation, extends cardiac xenograft survival

Recognition of a carbohydrate xenoepitope by human NKRP1A (CD161)

Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression.

The humoral response to xenografts is controlled by a restricted repertoire of immunoglobulin VH genes.

Acute vascular rejection of xenografts: roles of natural and elicited xenoreactive antibodies in activation of vascular endothelial cells and induction of procoagulant activity.

Disordered regulation of coagulation and platelet activation in xenotransplantation.

Coagulation and thrombotic disorders associated with pig organ and hematopoietic cell transplantation in nonhuman primates.

Molecular incompatibilities in hemostasis between swine and men--impact on xenografting.

Protective effects of recombinant human antithrombin III in pig-to-primate renal xenotransplantation.

Porcine cytomegalovirus and coagulopathy in pig-to-primate xenotransplantation.

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263-280

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10.1111/J.1399-3089.2009.00534.X

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5

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16

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2009-09-01T00:00:00Z

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26862529

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19796067

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2866107

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