Hematopoietic activity of granulocyte/macrophage colony-stimulating factor is dependent upon two distinct regions of the molecule: functional analysis based upon the activities of interspecies hybrid growth factors
about
Hematopoietic growth factors in clinical hematology.The receptor binding site of human interleukin-3 defined by mutagenesis and molecular modeling.Delivery of GM-CSF to Protect against Influenza Pneumonia.Structure-function analysis of interleukin-5 utilizing mouse/human chimeric molecules.Signal transduction mediated by growth hormone receptor and its chimeric molecules with the granulocyte colony-stimulating factor receptorCrucial role of the residue R280 at the F'-G' loop of the human granulocyte/macrophage colony-stimulating factor receptor alpha chain for ligand recognitionIdentification of functional domains of interleukin-3 by construction of primate interspecies chimera.Recombinant antibodies in bioactive peptide design.Design, synthesis and conformational analysis of hGM-CSF(13-31)-Gly-Pro-Gly-(103-116).A human interleukin 3 analog with increased biological and binding activities.The cytokine, granulocyte-macrophage colony-stimulating factor (GM-CSF), can deliver Bcl-XL as an extracellular fusion protein to protect cells from apoptosis and retain differentiation induction.Structural aspects of cytokine/receptor interactions.Structure-function relationships of interleukin-3. An analysis based on the function and binding characteristics of a series of interspecies chimera of gibbon and murine interleukin-3Structure-activity relationship study of human interleukin-3: role of the C-terminal region for biological activity.Rational design of granulocyte-macrophage colony-stimulating factor antagonist peptides.Residue 21 of human granulocyte-macrophage colony-stimulating factor is critical for biological activity and for high but not low affinity binding.Molecular modeling of the GM-CSF and IL-3 receptor complexes.Glycosylation, disulfide bond formation, and the presence of a WSXWS-like motif in the orf virus GIF protein are critical for maintaining the integrity of Binding to ovine granulocyte-macrophage colony-stimulating factor and interleukin-2.Identification of an antigenic domain near the C terminus of human granulocyte-macrophage colony-stimulating factor and its spatial localization.Human Granulocyte-Macrophage Colony-Stimulating Factor (hGM-CSF): Identification of a Binding Site for a Neutralizing Antibody
P2860
Q30444416-2F5C7CD8-C19E-47F2-A7BF-9B908127903DQ34437425-0F64402B-64D6-49F1-AE2C-4EE7D21D5398Q35553336-571D5612-C795-47B5-BBA3-9FE1B95A6D28Q35924746-CCEA4E23-9C83-4076-BC59-552EAAB609DAQ36031581-35A6A571-FA01-4197-B2C5-44F4446CF9FFQ36377279-699739E0-F085-40CF-9158-88DD4E965CABQ36716034-2FE971B7-9ADC-4984-9856-9C4034C677F5Q36720505-96DE3134-4B6C-40DE-9D5E-B7F3823E83CEQ36894416-376DB185-CE27-4A66-B0B2-E5321FF8C4D2Q37341411-1B60CDD7-6939-44C5-BB93-313AEDFEF2F3Q40168876-15BC50D3-1527-4C08-AF05-6B2EAA440369Q40374586-EF0EFFED-E5C4-4D55-8576-FBBD6DFB1F72Q41021171-E518CD67-8EE5-4216-B613-5C22D9DD1172Q41081708-0407CCFB-3C15-4290-BDC1-18ECC0A58C7FQ41229072-A3F7C937-4164-441C-94E5-2F76508AAA1BQ41518384-4D862AFA-1426-4C6A-B54F-BA7D1C93B2FDQ42844487-616D7BA8-E688-41EC-8BF4-856C609A043BQ42945533-D120D67F-7C85-4413-9972-E9043A4546C4Q47332912-7FADF0DE-42A7-4D37-93CD-770A31D626BEQ58039581-E94CE21A-5779-450C-B340-F462DBAA01E9
P2860
Hematopoietic activity of granulocyte/macrophage colony-stimulating factor is dependent upon two distinct regions of the molecule: functional analysis based upon the activities of interspecies hybrid growth factors
description
1989 nî lūn-bûn
@nan
1989 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1989 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
name
Hematopoietic activity of gran ...... rspecies hybrid growth factors
@ast
Hematopoietic activity of gran ...... rspecies hybrid growth factors
@en
type
label
Hematopoietic activity of gran ...... rspecies hybrid growth factors
@ast
Hematopoietic activity of gran ...... rspecies hybrid growth factors
@en
prefLabel
Hematopoietic activity of gran ...... rspecies hybrid growth factors
@ast
Hematopoietic activity of gran ...... rspecies hybrid growth factors
@en
P2093
P2860
P356
P1476
Hematopoietic activity of gran ...... rspecies hybrid growth factors
@en
P2093
K Kaushansky
S G Shoemaker
P2860
P304
P356
10.1073/PNAS.86.4.1213
P407
P577
1989-02-01T00:00:00Z