Regorafenib inhibits colorectal tumor growth through PUMA-mediated apoptosis.
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Ramucirumab in metastatic colorectal cancer: evidence to date and place in therapyYM155 Down-Regulates Survivin and Induces P53 Up-Regulated Modulator of Apoptosis (PUMA)-Dependent in Oral Squamous Cell Carcinoma Cells.Regorafenib inhibited gastric cancer cells growth and invasion via CXCR4 activated Wnt pathwayMonitoring Cell Death in Regorafenib-Treated Experimental Colon Carcinomas Using Annexin-Based Optical Fluorescence Imaging Validated by Perfusion MRI.PUMA mediates the combinational therapy of 5-FU and NVP-BEZ235 in colon cancerAntitumor activity of the multikinase inhibitor regorafenib in patient-derived xenograft models of gastric cancer.Regorafenib with a fluoropyrimidine for metastatic colorectal cancer after progression on multiple 5-FU-containing combination therapies and regorafenib monotherapy.Targeting Transforming Growth Factor-Beta1 (TGF-β1) Inhibits Tumorigenesis of Anaplastic Thyroid Carcinoma Cells Through ERK1/2-NFκkB-PUMA Signaling.FBW7 mutations mediate resistance of colorectal cancer to targeted therapies by blocking Mcl-1 degradation.Idelalisib induces PUMA-dependent apoptosis in colon cancer cells.Pazopanib, a novel multi-kinase inhibitor, shows potent antitumor activity in colon cancer through PUMA-mediated apoptosis.Single-cell functional and chemosensitive profiling of combinatorial colorectal therapy in zebrafish xenografts.Synthesis and Evaluation of Novel 2-Pyrrolidone-Fused (2-Oxoindolin-3-ylidene)methylpyrrole Derivatives as Potential Multi-Target Tyrosine Kinase Receptor Inhibitors.PHD1 regulates p53-mediated colorectal cancer chemoresistance.Regorafenib diminishes the expression and secretion of angiogenesis and metastasis associated proteins and inhibits cell invasion via NF-κB inactivation in SK-Hep1 cellsKnockdown of delta-5-desaturase promotes the anti-cancer activity of dihomo-γ-linolenic acid and enhances the efficacy of chemotherapy in colon cancer cells expressing COX-2.Silence of long noncoding RNA PANDAR switches low-dose curcumin-induced senescence to apoptosis in colorectal cancer cells.The cytotoxic effects of regorafenib in combination with protein kinase D inhibition in human colorectal cancer cells.Deguelin induces PUMA-mediated apoptosis and promotes sensitivity of lung cancer cells (LCCs) to doxorubicin (Dox).Expression and clinical significance of ATM and PUMA gene in patients with colorectal cancer.Regorafenib overcomes chemotherapeutic multidrug resistance mediated by ABCB1 transporter in colorectal cancer: In vitro and in vivo study.Mcl-1 Degradation Is Required for Targeted Therapeutics to Eradicate Colon Cancer Cells.Regorafenib inhibits tumor progression through suppression of ERK/NF-κB activation in hepatocellular carcinoma bearing mice.Evolution of regorafenib from bench to bedside in colorectal cancer: Is it an attractive option or merely a "me too" drug?Development and validation of an analytical method for regorafenib and its metabolites in mouse plasma.Effect of taurine on cell proliferation and apoptosis human lung cancer A549 cells.FGFR2 amplification is predictive of sensitivity to regorafenib in gastric and colorectal cancers in vitro.MEK inhibitors induce apoptosis via FoxO3a-dependent PUMA induction in colorectal cancer cellsIpatasertib, a novel Akt inhibitor, induces transcription factor FoxO3a and NF-κB directly regulates PUMA-dependent apoptosis
P2860
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P2860
Regorafenib inhibits colorectal tumor growth through PUMA-mediated apoptosis.
description
2014 nî lūn-bûn
@nan
2014 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Regorafenib inhibits colorectal tumor growth through PUMA-mediated apoptosis.
@ast
Regorafenib inhibits colorectal tumor growth through PUMA-mediated apoptosis.
@en
type
label
Regorafenib inhibits colorectal tumor growth through PUMA-mediated apoptosis.
@ast
Regorafenib inhibits colorectal tumor growth through PUMA-mediated apoptosis.
@en
prefLabel
Regorafenib inhibits colorectal tumor growth through PUMA-mediated apoptosis.
@ast
Regorafenib inhibits colorectal tumor growth through PUMA-mediated apoptosis.
@en
P2860
P1476
Regorafenib inhibits colorectal tumor growth through PUMA-mediated apoptosis
@en
P2093
Dongshi Chen
P2860
P304
P356
10.1158/1078-0432.CCR-13-2944
P407
P577
2014-04-24T00:00:00Z