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Molecular architecture of a kinetochore-microtubule attachment site

Molecular architecture of a kinetochore-microtubule attachment site

http://www.wikidata.org/entity/Q33839309

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The monopolin complex crosslinks kinetochore components to regulate chromosome-microtubule attachments Linking kinetochore-microtubule binding to the spindle checkpoint Orientation and structure of the Ndc80 complex on the microtubule lattice.The kinetochore interaction network (KIN) of ascomycetes Review series: The functions and consequences of force at kinetochores Reconstituting the kinetochore–microtubule interface: what, why, and how From equator to pole: splitting chromosomes in mitosis and meiosis Visualizing kinetochore architecture EB1 regulates attachment of Ska1 with microtubules by forming extended structures on the microtubule lattice Monopolin subunit Csm1 associates with MIND complex to establish monopolar attachment of sister kinetochores at meiosis I Implications for kinetochore-microtubule attachment from the structure of an engineered Ndc80 complex.The Ndc80/HEC1 complex is a contact point for kinetochore-microtubule attachment Structural and Functional Dissection of Mif2p, a Conserved DNA-binding Kinetochore Protein The Ndc80 kinetochore complex forms oligomeric arrays along microtubules A structural basis for kinetochore recruitment of the Ndc80 complex via two distinct centromere receptors RWD domain: a recurring module in kinetochore architecture shown by a Ctf19–Mcm21 complex structure An Iml3-Chl4 Heterodimer Links the Core Centromere to Factors Required for Accurate Chromosome Segregation Bending the rules: widefield microscopy and the Abbe limit of resolution.Roles for the conserved spc105p/kre28p complex in kinetochore-microtubule binding and the spindle assembly checkpoint.The budding yeast point centromere associates with two Cse4 molecules during mitosis.Dual mechanisms regulate the recruitment of spindle assembly checkpoint proteins to the budding yeast kinetochore Bub1 kinase and Sgo1 modulate pericentric chromatin in response to altered microtubule dynamics Chromosome congression by Kinesin-5 motor-mediated disassembly of longer kinetochore microtubules.Mimicking Ndc80 phosphorylation triggers spindle assembly checkpoint signalling Structure of the Saccharomyces cerevisiae Hrr25:Mam1 monopolin subcomplex reveals a novel kinase regulator.Quantitative proteomic analysis of purified yeast kinetochores identifies a PP1 regulatory subunit A Cell Biological Perspective on Past, Present and Future Investigations of the Spindle Assembly Checkpoint Centromere-proximal crossovers are associated with precocious separation of sister chromatids during meiosis in Saccharomyces cerevisiae Mechanism of Ska Recruitment by Ndc80 Complexes to Kinetochores.The quantitative architecture of centromeric chromatin Looping in on Ndc80 - how does a protein loop at the kinetochore control chromosome segregation?The Ndc80 complex: integrating the kinetochore's many movements.Kinetochore attachments require an interaction between unstructured tails on microtubules and Ndc80(Hec1).Protein architecture of the human kinetochore microtubule attachment site.Direct physical study of kinetochore-microtubule interactions by reconstitution and interrogation with an optical force clamp.The yeast DNA damage checkpoint proteins control a cytoplasmic response to DNA damage Dynactin function in mitotic spindle positioning.Different assemblies of the DAM1 complex follow shortening microtubules by distinct mechanisms.The Dam1 ring binds microtubules strongly enough to be a processive as well as energy-efficient coupler for chromosome motion.Motor- and tail-dependent targeting of dynein to microtubule plus ends and the cell cortex.

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P2860

Molecular architecture of a kinetochore-microtubule attachment site

http://www.wikidata.org/entity/Q33839309

description

2006 nî lūn-bûn

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2006 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2006 թվականի մայիսին հրատարակված գիտական հոդված

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2006年の論文

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Molecular architecture of a kinetochore-microtubule attachment site

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Molecular architecture of a kinetochore-microtubule attachment site

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Molecular architecture of a kinetochore-microtubule attachment site

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Molecular architecture of a kinetochore-microtubule attachment site

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Molecular architecture of a kinetochore-microtubule attachment site

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Nature Cell Biology

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Molecular architecture of a kinetochore-microtubule attachment site

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Edward D Salmon

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Jeffrey N Molk

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P2860

Architecture of the human ndc80-hec1 complex, a critical constituent of the outer kinetochore

Hec1 and nuf2 are core components of the kinetochore outer plate essential for organizing microtubule attachment sites.

A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae

Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae

Kinetochore protein interactions and their regulation by the Aurora kinase Ipl1p

The N terminus of the centromere H3-like protein Cse4p performs an essential function distinct from that of the histone fold domain.

The yeast DASH complex forms closed rings on microtubules.

The unstable F-box protein p58-Ctf13 forms the structural core of the CBF3 kinetochore complex

Interactions between centromere complexes in Saccharomyces cerevisiae.

A putative protein complex consisting of Ctf19, Mcm21, and Okp1 represents a missing link in the budding yeast kinetochore.

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