AID induces double-strand breaks at immunoglobulin switch regions and c-MYC causing chromosomal translocations in yeast THO mutants.
about
Out of balance: R-loops in human diseaseTranscriptional stalling in B-lymphocytes: a mechanism for antibody diversification and maintenance of genomic integrityRNA Exosome Regulates AID DNA Mutator Activity in the B Cell GenomeGenomic hallmarks of genes involved in chromosomal translocations in hematological cancer.RNase H enables efficient repair of R-loop induced DNA damage.Yeast pol4 promotes tel1-regulated chromosomal translocations.Regulation of AID, the B-cell genome mutator.The spliceosome-associated protein Nrl1 suppresses homologous recombination-dependent R-loop formation in fission yeast.The SAGA Deubiquitination Module Promotes DNA Repair and Class Switch Recombination through ATM and DNAPK-Mediated γH2AX Formation.Making a long story short: noncoding RNAs and chromosome change.Transcription and recombination: when RNA meets DNA.Genome-wide function of THO/TREX in active genes prevents R-loop-dependent replication obstacles.Guanine repeat-containing sequences confer transcription-dependent instability in an orientation-specific manner in yeast.Arginine methylation facilitates the recruitment of TOP3B to chromatin to prevent R loop accumulation.RNA Polymerase Collision versus DNA Structural Distortion: Twists and Turns Can Cause Break FailureLong-term arsenite exposure induces premature senescence in B cell lymphoma A20 cells.R Loops and Links to Human Disease.Replication Fork Protection Factors Controlling R-Loop Bypass and SuppressionQmRLFS-finder: a model, web server and stand-alone tool for prediction and analysis of R-loop forming sequences.Erroneous class switching and false VDJ recombination: molecular dissection of t(8;14)/MYC-IGH translocations in Burkitt-type lymphoblastic leukemia/B-cell lymphoma.Cytosine deamination and base excision repair cause R-loop-induced CAG repeat fragility and instability in Saccharomyces cerevisiae.Topoisomerase I and Genome Stability: The Good and the Bad.
P2860
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P2860
AID induces double-strand breaks at immunoglobulin switch regions and c-MYC causing chromosomal translocations in yeast THO mutants.
description
2011 nî lūn-bûn
@nan
2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
AID induces double-strand brea ...... ocations in yeast THO mutants.
@ast
AID induces double-strand brea ...... ocations in yeast THO mutants.
@en
type
label
AID induces double-strand brea ...... ocations in yeast THO mutants.
@ast
AID induces double-strand brea ...... ocations in yeast THO mutants.
@en
prefLabel
AID induces double-strand brea ...... ocations in yeast THO mutants.
@ast
AID induces double-strand brea ...... ocations in yeast THO mutants.
@en
P2860
P1433
P1476
AID induces double-strand brea ...... ocations in yeast THO mutants.
@en
P2093
Belén Gómez-González
P2860
P304
P356
10.1371/JOURNAL.PGEN.1002009
P577
2011-02-24T00:00:00Z