Transcriptional activation of the telomerase hTERT gene by human papillomavirus type 16 E6 oncoprotein.
about
Immortalization of human mammary epithelial cells is associated with inactivation of the p14ARF-p53 pathwayThe global transcriptional effects of the human papillomavirus E6 protein in cervical carcinoma cell lines are mediated by the E6AP ubiquitin ligase.Human telomerase and its regulationIdentification of a novel telomerase repressor that interacts with the human papillomavirus type-16 E6/E6-AP complexCytoplasmic poly(A) binding proteins regulate telomerase activity and cell growth in human papillomavirus type 16 E6-expressing keratinocytesNFX1 interacts with mSin3A/histone deacetylase to repress hTERT transcription in keratinocytesTranscription Regulation of the Human Telomerase Reverse Transcriptase (hTERT) GeneImmortalization of Primary Keratinocytes and Its Application to Skin ResearchFunctional Roles of E6 and E7 Oncoproteins in HPV-Induced Malignancies at Diverse Anatomical SitesO-linked GlcNAcylation elevated by HPV E6 mediates viral oncogenesisPapillomavirus E6 oncoproteins.The human papillomavirus 16 E6 protein binds to Fas-associated death domain and protects cells from Fas-triggered apoptosis.Human papillomavirus E6 and Myc proteins associate in vivo and bind to and cooperatively activate the telomerase reverse transcriptase promoterThe mRNA decay factor tristetraprolin (TTP) induces senescence in human papillomavirus-transformed cervical cancer cells by targeting E6-AP ubiquitin ligase.Human telomeres maintain their overhang length at senescence.Human papillomaviruses: genetic basis of carcinogenicity.High-resolution genomic profiling of human papillomavirus-associated vulval neoplasia.Activating transcription factor 3 activates p53 by preventing E6-associated protein from binding to E6.Potent anti-tumor effect generated by a novel human papillomavirus (HPV) antagonist peptide reactivating the pRb/E2F pathway.Counseling the patient with potentially HPV-related newly diagnosed head and neck cancerLocalisation of human papillomavirus 16 E7 oncoprotein changes with cell confluence.Integration of interferon-alpha/beta signalling to p53 responses in tumour suppression and antiviral defence.Genetic analysis of high-risk e6 in episomal maintenance of human papillomavirus genomes in primary human keratinocytes.Endogenous human papillomavirus E6 and E7 proteins differentially regulate proliferation, senescence, and apoptosis in HeLa cervical carcinoma cellsThe human papillomavirus E6 protein and its contribution to malignant progression.Regulation of the human telomerase reverse transcriptase gene.Complex regulatory mechanisms of telomerase activity in normal and cancer cells: how can we apply them for cancer therapy?Tiptoeing to chromosome tips: facts, promises and perils of today's human telomere biology.Human papillomavirus type 31 E5 protein supports cell cycle progression and activates late viral functions upon epithelial differentiation.Warts, cancer and ubiquitylation: lessons from the papillomaviruses.Viral carcinogenesis: factors inducing DNA damage and virus integrationBerberine modulates AP-1 activity to suppress HPV transcription and downstream signaling to induce growth arrest and apoptosis in cervical cancer cells.Human papillomaviruses: targeting differentiating epithelial cells for malignant transformation.Targeting the human papillomavirus E6 and E7 oncogenes through expression of the bovine papillomavirus type 1 E2 protein stimulates cellular motility.Immunosuppressive tumor microenvironment in cervical cancer patientsCervical epithelial cells transduced with the papillomavirus E6/E7 oncogenes maintain stable levels of oncoprotein expression but exhibit progressive, major increases in hTERT gene expression and telomerase activity.Detection of genomic amplification of the human telomerase gene (TERC) in cytologic specimens as a genetic test for the diagnosis of cervical dysplasiaMolecular genetics of human cervical cancer: role of papillomavirus and the apoptotic cascade.Mechanisms of human papillomavirus-induced oncogenesis.Transcriptomic analyses of genes differentially expressed by high-risk and low-risk human papilloma virus E6 oncoproteins
P2860
Q24308746-F3F58CF7-E3AF-490A-B3B7-674300654B73Q24521626-E16F47E7-BF4F-4B7E-A0AE-68ABB6580925Q24533247-2F22FD9B-C337-4435-96C8-BCF651C4F35CQ24561609-7FB4F100-575A-4DB3-9818-0859D1379EE1Q24627249-D4E7EBB9-BE2C-4463-8700-40BEE9FFCAA3Q24650992-1C99B27C-61F8-49C2-A96B-3107F2C44D55Q26739925-A1FE8113-8C23-47A7-9C46-1086A2A0BC50Q26786026-337B352F-0C94-4295-92F7-BD9B82DA8BAFQ28078631-FDFF6619-6367-40C5-BEB8-C6B170C5E09BQ28829215-D576AD60-F038-4E36-85BF-F947D90A62D9Q30410553-0A34C276-937B-4B1A-B8F5-607046343BA9Q33292139-ED6907E1-99B0-4944-A784-EFF0AEADAD58Q33292282-158E3DB3-9F45-4A47-937B-908EFB651903Q33627886-B43D256D-8094-4701-9A0B-FD78ED6153C9Q33707650-2BE1B013-D1B0-46C1-9710-232536D00708Q33714501-38AE649D-A7DB-43D6-ACB0-B168D03DCAA3Q33747413-9CCDB1F5-E44B-4DE1-B656-6DCDDFB1C586Q33800021-626AA9CE-0179-4FE9-80C6-7521430CD327Q33851368-6BC300FA-6E71-47AA-B89A-9BC97E6E8170Q33908473-C8161624-1DD1-40DD-8476-774A2870C670Q33954971-AB67555E-5BDF-4F85-8257-B091C14ADDCAQ33967257-729F3213-BF2D-474D-99F8-1A35CA62E255Q34355987-D9B0C3CD-EE5B-4635-8277-FE49884E3521Q34465477-E716B978-6826-4B3B-8A3E-929E03E547B5Q34468780-4D24B1FF-1394-461F-AF00-A31520D13FC7Q34535621-A02EA2F6-BA82-40EF-B9C1-151E70278213Q34535740-F1CF4032-8BEB-460E-971C-F062EC3CF419Q34655822-E6E5FBBB-0AF6-46B4-80F7-6A7BF16F4C6EQ34757163-513DADDF-72AA-4385-8A3D-3E3922482A8CQ34767225-8A915E24-9484-4CCB-A341-261511FB9DB0Q34774880-4BD1007B-99DE-4709-B51C-1FF63C3931DDQ34995160-1BEB3EA9-ADA1-4BDE-96DC-AB734CF9CE8AQ35196630-07047CDC-2F0E-4D57-A9FB-2D569444C7D9Q35274806-082C581F-F6F1-41A3-B2E6-782C48A241B4Q35603131-80ECC0A4-8CC7-4135-89FC-5F4B2860B4F6Q35789014-2C6C2BD8-5D87-4188-966C-DA918128D23BQ35792128-85AB3AB8-1C99-4112-A1C9-72BBBCD7337AQ35902272-72C86613-727F-465C-BB9A-0808108DF14BQ35915935-D0394E61-EBA1-44C8-9364-E31BF72EC788Q36064347-BB6D3AD2-529E-4C3C-A8CB-A57821E8A878
P2860
Transcriptional activation of the telomerase hTERT gene by human papillomavirus type 16 E6 oncoprotein.
description
2001 nî lūn-bûn
@nan
2001 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Transcriptional activation of ...... avirus type 16 E6 oncoprotein.
@ast
Transcriptional activation of ...... avirus type 16 E6 oncoprotein.
@en
type
label
Transcriptional activation of ...... avirus type 16 E6 oncoprotein.
@ast
Transcriptional activation of ...... avirus type 16 E6 oncoprotein.
@en
prefLabel
Transcriptional activation of ...... avirus type 16 E6 oncoprotein.
@ast
Transcriptional activation of ...... avirus type 16 E6 oncoprotein.
@en
P2093
P2860
P1433
P1476
Transcriptional activation of ...... avirus type 16 E6 oncoprotein.
@en
P2093
I Horikawa
J C Barrett
R Schlegel
P2860
P304
P356
10.1128/JVI.75.9.4467-4472.2001
P577
2001-05-01T00:00:00Z