Requirement of Smurf-mediated endocytosis of Patched1 in sonic hedgehog signal reception.
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Trafficking to the primary cilium membrane.Patched-1 proapoptotic activity is downregulated by modification of K1413 by the E3 ubiquitin-protein ligase Itchy homolog.Inhibitors of endocytosis prevent Wnt/Wingless signalling by reducing the level of basal β-catenin/ArmadilloNotch activity modulates the responsiveness of neural progenitors to sonic hedgehog signalingRegulation of Hedgehog signaling by ubiquitination.The Hedgehog pathway: role in cell differentiation, polarity and proliferationSmoothened determines β-arrestin-mediated removal of the G protein-coupled receptor Gpr161 from the primary ciliumHedgehog signaling activation induces stem cell proliferation and hormone release in the adult pituitary gland.The role of ciliary trafficking in Hedgehog receptor signaling.Suppressor of Fused Chaperones Gli Proteins To Generate Transcriptional Responses to Sonic Hedgehog Signaling.KIF13B establishes a CAV1-enriched microdomain at the ciliary transition zone to promote Sonic hedgehog signalling.An Actin Network Dispatches Ciliary GPCRs into Extracellular Vesicles to Modulate Signaling.Hedgehog Signal Transduction: Key Players, Oncogenic Drivers, and Cancer Therapy.Ubiquitin-Dependent Regulation of Stem Cell Biology.Activities of the Cytoplasmic Domains of Patched-1 Modulate but Are Not Essential for the Regulation of Canonical Hedgehog Signaling.Bone Morphogenic Protein Type 2 Receptor Mutation-Independent Mechanisms of Disrupted Bone Morphogenetic Protein Signaling in Idiopathic Pulmonary Arterial Hypertension.Control of the dynamics and homeostasis of the Drosophila Hedgehog receptor Patched by two C2-WW-HECT-E3 Ubiquitin ligases.Suppressor of fused (Sufu) promotes epithelial-mesenchymal transition (EMT) in cervical squamous cell carcinoma.PTCH1 inhibits accumulation of SMO in the primary cilium in the absence of Hh signalSMURF1/2 bind PTCH1SMURF1/2 ubiquitinates PTCH1SMURF1/2 dissociates from ub-PTCH1PTCH is internalizedADRBK1 phosphorylates SMO dimerDeSUMOylation of Gli1 by SENP1 Attenuates Sonic Hedgehog Signaling.The latent geometry of the human protein interaction network.The hedgehog pathway in nonalcoholic fatty liver disease.Emerging Roles of DYRK Kinases in Embryogenesis and Hedgehog Pathway Control.Generation of Smurf2 Conditional Knockout Mice.The E3 ubiquitin ligase SMURF1 regulates cell-fate specification and outflow tract septation during mammalian heart development.
P2860
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P2860
Requirement of Smurf-mediated endocytosis of Patched1 in sonic hedgehog signal reception.
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2014 nî lūn-bûn
@nan
2014 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2014年の論文
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2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Requirement of Smurf-mediated endocytosis of Patched1 in sonic hedgehog signal reception.
@ast
Requirement of Smurf-mediated endocytosis of Patched1 in sonic hedgehog signal reception.
@en
type
label
Requirement of Smurf-mediated endocytosis of Patched1 in sonic hedgehog signal reception.
@ast
Requirement of Smurf-mediated endocytosis of Patched1 in sonic hedgehog signal reception.
@en
prefLabel
Requirement of Smurf-mediated endocytosis of Patched1 in sonic hedgehog signal reception.
@ast
Requirement of Smurf-mediated endocytosis of Patched1 in sonic hedgehog signal reception.
@en
P2093
P2860
P356
P1433
P1476
Requirement of Smurf-mediated endocytosis of Patched1 in sonic hedgehog signal reception.
@en
P2093
Liu-Ya Tang
Qiu-Hong Shen
Steven Y Cheng
Ting-Ting Yu
Ying E Zhang
P2860
P356
10.7554/ELIFE.02555
P407
P577
2014-06-12T00:00:00Z