An orally available, small-molecule polymerase inhibitor shows efficacy against a lethal morbillivirus infection in a large animal model.
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Measles Virus Fusion Protein: Structure, Function and InhibitionOrganization, Function, and Therapeutic Targeting of the Morbillivirus RNA-Dependent RNA Polymerase ComplexMorbillivirus Experimental Animal Models: Measles Virus Pathogenesis Insights from Canine Distemper VirusSequential conformational changes in the morbillivirus attachment protein initiate the membrane fusion processPrevention of measles virus infection by intranasal delivery of fusion inhibitor peptidesInfectious disease: small molecule combats measles virus.Canine distemper virus as a threat to wild tigers in Russia and across their range.Replication-Competent Influenza Virus and Respiratory Syncytial Virus Luciferase Reporter Strains Engineered for Co-Infections Identify Antiviral Compounds in Combination Screens.Morbillivirus infections: an introduction.The paramyxovirus polymerase complex as a target for next-generation anti-paramyxovirus therapeutics.Polymerases of paramyxoviruses and pneumoviruses.Mutations in the Fusion Protein of Measles Virus That Confer Resistance to the Membrane Fusion Inhibitors Carbobenzoxy-d-Phe-l-Phe-Gly and 4-Nitro-2-Phenylacetyl Amino-Benzamide.Structure of the L Protein of Vesicular Stomatitis Virus from Electron Cryomicroscopy.A pioneering countermeasure against measles virusThe Unstructured Paramyxovirus Nucleocapsid Protein Tail Domain Modulates Viral Pathogenesis through Regulation of Transcriptase Activity.Promotion of virus assembly and organization by the measles virus matrix protein.Orally Efficacious Broad-Spectrum Ribonucleoside Analog Inhibitor of Influenza and Respiratory Syncytial Viruses
P2860
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P2860
An orally available, small-molecule polymerase inhibitor shows efficacy against a lethal morbillivirus infection in a large animal model.
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2014 nî lūn-bûn
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2014 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի ապրիլին հրատարակված գիտական հոդված
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2014年の論文
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2014年論文
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2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
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2014年论文
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name
An orally available, small-mol ...... ction in a large animal model.
@ast
An orally available, small-mol ...... ction in a large animal model.
@en
type
label
An orally available, small-mol ...... ction in a large animal model.
@ast
An orally available, small-mol ...... ction in a large animal model.
@en
prefLabel
An orally available, small-mol ...... ction in a large animal model.
@ast
An orally available, small-mol ...... ction in a large animal model.
@en
P2093
P2860
P1476
An orally available, small-mol ...... ection in a large animal model
@en
P2093
Aiming Sun
Dennis C Liotta
Elise S Hovingh
G Prabhakar Reddy
George Painter
Manohar T Saindane
Michael G Natchus
Richard F Arrendale
Richard K Plemper
P2860
P304
P356
10.1126/SCITRANSLMED.3008517
P407
P577
2014-04-01T00:00:00Z