Prostaglandin D2 induces nuclear import of the sex-determining factor SOX9 via its cAMP-PKA phosphorylation. - Wikidata - wikimedia - TriplyDB

Prostaglandin D2 induces nuclear import of the sex-determining factor SOX9 via its cAMP-PKA phosphorylation.

Prostaglandin D2 induces nuclear import of the sex-determining factor SOX9 via its cAMP-PKA phosphorylation.

http://www.wikidata.org/entity/Q33841852

about

Fgf9 and Wnt4 act as antagonistic signals to regulate mammalian sex determination SOX9, through interaction with microphthalmia-associated transcription factor (MITF) and OTX2, regulates BEST1 expression in the retinal pigment epithelium Building the mammalian testis: origins, differentiation, and assembly of the component cell populations Enzymes of the cyclooxygenase pathways of prostanoid biosynthesis Control of cell fate and differentiation by Sry-related high-mobility-group box (Sox) transcription factors Cell fate commitment during mammalian sex determination Structural Basis of the Catalytic Mechanism Operating in Open-Closed Conformers of Lipocalin Type Prostaglandin D Synthase The PGD2 pathway, independently of FGF9, amplifies SOX9 activity in Sertoli cells during male sexual differentiation Genetic control of testis development Insulin and IGF1 receptors are essential for XX and XY gonadal differentiation and adrenal development in mice Global analysis of host-pathogen interactions that regulate early-stage HIV-1 replication Unilateral cryptorchidism in mice mutant for Ptgds.The Maestro (Mro) gene is dispensable for normal sexual development and fertility in mice Loss of mitogen-activated protein kinase kinase kinase 4 (MAP3K4) reveals a requirement for MAPK signalling in mouse sex determination.To beta or not to beta: canonical beta-catenin signaling pathway and ovarian development The road to maleness: from testis to Wolffian duct.Sox proteins in melanocyte development and melanoma.Profiling spermatogenic failure in adult testes bearing Sox9-deficient Sertoli cells identifies genes involved in feminization, inflammation and stress.Regulation of male sex determination: genital ridge formation and Sry activation in mice.Hematopoietic-Prostaglandin D2 synthase through PGD2 production is involved in the adult ovarian physiology.Dexamethasone protects neonatal hypoxic-ischemic brain injury via L-PGDS-dependent PGD2-DP1-pERK signaling pathway.The emerging role of insulin-like growth factors in testis development and function.Reprogramming of Sertoli cells to fetal-like Leydig cells by Wt1 ablation Sox9 is expressed in mouse multipotent retinal progenitor cells and functions in Müller glial cell development.SOX9 is a key player in ultraviolet B-induced melanocyte differentiation and pigmentation The Role of Prostaglandins and COX-Enzymes in Chondrogenic Differentiation of ATDC5 Progenitor Cells.Hyper sensitive protein detection by Tandem-HTRF reveals Cyclin D1 dynamics in adult mouse The makings of maleness: towards an integrated view of male sexual development.Phosphorylation of Sox9 is required for neural crest delamination and is regulated downstream of BMP and canonical Wnt signaling.PGD(2) DP1 receptor protects brain from ischemia-reperfusion injury.Signaling Cascades Governing Cdc42-Mediated Chondrogenic Differentiation and Mensenchymal Condensation H-rev107 regulates prostaglandin D2 synthase-mediated suppression of cellular invasion in testicular cancer cells.SRY and the standoff in sex determination The molecular and cellular basis of gonadal sex reversal in mice and humans.Control of chondrogenesis by the transcription factor Sox9.Upregulation of SOX9 inhibits the growth of human and mouse melanomas and restores their sensitivity to retinoic acid Inherited human sex reversal due to impaired nucleocytoplasmic trafficking of SRY defines a male transcriptional threshold.SoxE factors as multifunctional neural crest regulatory factors.A role for estrogen in somatic cell fate of the mammalian gonad.Early gonadogenesis in mammals: significance of long and narrow gonadal structure.

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Prostaglandin D2 induces nuclear import of the sex-determining factor SOX9 via its cAMP-PKA phosphorylation.

http://www.wikidata.org/entity/Q33841852

description

2005 nî lūn-bûn

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2005 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2005 թվականի մայիսին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年论文

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Prostaglandin D2 induces nucle ...... its cAMP-PKA phosphorylation.

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Prostaglandin D2 induces nucle ...... its cAMP-PKA phosphorylation.

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SJ.EMBOJ.7600660

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The EMBO Journal

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Prostaglandin D2 induces nucle ...... its cAMP-PKA phosphorylation.

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Brigitte Boizet-Bonhoure

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Catherine Méjean

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Cécile Notarnicola

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Francis Poulat

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Laurie Thevenet

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Philippe Berta

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Safia Malki

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Serge Nef

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Stéphan Gasca

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P2860

Phosphorylation of SOX9 by cyclic AMP-dependent protein kinase A enhances SOX9's ability to transactivate a Col2a1 chondrocyte-specific enhancer

Prostaglandin D2 selectively induces chemotaxis in T helper type 2 cells, eosinophils, and basophils via seven-transmembrane receptor CRTH2

A gene from the human sex-determining region encodes a protein with homology to a conserved DNA-binding motif

Molecular cloning and characterization of the human prostanoid DP receptor

Direct interaction of SRY-related protein SOX9 and steroidogenic factor 1 regulates transcription of the human anti-Müllerian hormone gene

SOX9 interacts with a component of the human thyroid hormone receptor-associated protein complex.

Compound effects of point mutations causing campomelic dysplasia/autosomal sex reversal upon SOX9 structure, nuclear transport, DNA binding, and transcriptional activation

Disruption of testis cords by cyclopamine or forskolin reveals independent cellular pathways in testis organogenesis

Campomelic dysplasia and autosomal sex reversal caused by mutations in an SRY-related gene

Autosomal sex reversal and campomelic dysplasia are caused by mutations in and around the SRY-related gene SOX9

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1798-1809

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10.1038/SJ.EMBOJ.7600660

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10

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24

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7852454

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15889150

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phosphorylation

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1142593

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